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Stefano Costanzi
Stefano Costanzi
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Title
Cited by
Cited by
Year
Adenosine deaminase: functional implications and different classes of inhibitors
G Cristalli, S Costanzi, C Lambertucci, G Lupidi, S Vittori, R Volpini, ...
Medicinal research reviews 21 (2), 105-128, 2001
4312001
Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation
G Trivellin, AF Daly, FR Faucz, B Yuan, L Rostomyan, DO Larco, ...
New England Journal of Medicine 371 (25), 2363-2374, 2014
3232014
Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling
S Costanzi, L Mamedova, ZG Gao, KA Jacobson
Journal of medicinal chemistry 47 (22), 5393-5404, 2004
1772004
Discovery of novel agonists and antagonists of the free fatty acid receptor 1 (FFAR1) using virtual screening
IG Tikhonova, CS Sum, S Neumann, S Engel, BM Raaka, S Costanzi, ...
Journal of medicinal chemistry 51 (3), 625-633, 2008
1712008
Nerve agents: what they are, how they work, how to counter them
S Costanzi, JH Machado, M Mitchell
ACS chemical neuroscience 9 (5), 873-885, 2018
1702018
On the Applicability of GPCR Homology Models to Computer-Aided Drug Discovery: A Comparison between In Silico and Crystal Structures of the β2-Adrenergic …
S Costanzi
Journal of medicinal chemistry 51 (10), 2907-2914, 2008
1622008
Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3 …
J Jiang, K Ghoreschi, F Deflorian, Z Chen, M Perreira, M Pesu, J Smith, ...
Journal of medicinal chemistry 51 (24), 8012-8018, 2008
1432008
Identification of residues important for agonist recognition and activation in GPR40
CS Sum, IG Tikhonova, S Neumann, S Engel, BM Raaka, S Costanzi, ...
Journal of Biological Chemistry 282 (40), 29248-29255, 2007
1402007
Prediction of passive blood–brain partitioning: straightforward and effective classification models based on in silico derived physicochemical descriptors
S Vilar, M Chakrabarti, S Costanzi
Journal of Molecular Graphics and Modelling 28 (8), 899-903, 2010
1392010
Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library
S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ...
Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017
1312017
N 6-Alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A3 receptor and a starting point for searching A2B ligands
R Volpini, S Costanzi, C Lambertucci, S Taffi, S Vittori, KN Klotz, G Cristalli
Journal of medicinal chemistry 45 (15), 3271-3279, 2002
1262002
A2B adenosine receptor blockade inhibits growth of prostate cancer cells
Q Wei, S Costanzi, R Balasubramanian, ZG Gao, KA Jacobson
Purinergic signalling 9, 271-280, 2013
1202013
A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin …
H Jäschke, S Neumann, S Moore, CJ Thomas, AO Colson, S Costanzi, ...
Journal of Biological Chemistry 281 (15), 9841-9844, 2006
1162006
A low-molecular-weight antagonist for the human thyrotropin receptor with therapeutic potential for hyperthyroidism
S Neumann, G Kleinau, S Costanzi, S Moore, J Jiang, BM Raaka, ...
Endocrinology 149 (12), 5945-5950, 2008
1132008
Bidirectional, iterative approach to the structural delineation of the functional “chemoprint” in GPR40 for agonist recognition
IG Tikhonova, CS Sum, S Neumann, CJ Thomas, BM Raaka, S Costanzi, ...
Journal of medicinal chemistry 50 (13), 2981-2989, 2007
1122007
Medicinal chemistry and pharmacology of A2B adenosine receptors
R Volpini, S Costanzi, S Vittori, G Cristalli, KN Klotz
Current topics in medicinal chemistry 3 (4), 427-443, 2003
1122003
Synthesis and Biological Activity of a New Series of N 6-Arylcarbamoyl, 2-(Ar) alkynyl-N 6-arylcarbamoyl, and N 6-Carboxamido Derivatives of Adenosine-5 ‘-N-ethyluronamide as …
PG Baraldi, B Cacciari, MJ Pineda de Las Infantas, R Romagnoli, ...
Journal of medicinal chemistry 41 (17), 3174-3185, 1998
1121998
New substituted 9-alkylpurines as adenosine receptor ligands
E Camaioni, S Costanzi, S Vittori, R Volpini, KN Klotz, G Cristalli
Bioorganic & medicinal chemistry 6 (5), 523-533, 1998
1111998
New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors
KA Jacobson, S Costanzi
Molecular pharmacology 82 (3), 361-371, 2012
1042012
Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure− activity relationships and selective …
S Moore, H Jaeschke, G Kleinau, S Neumann, S Costanzi, J Jiang, ...
Journal of medicinal chemistry 49 (13), 3888-3896, 2006
1032006
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