Rachid Essalmani
Rachid Essalmani
Research Associate, IRCM, Montreal
Verified email at ircm.qc.ca
Title
Cited by
Cited by
Year
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol
S Benjannet, D Rhainds, R Essalmani, J Mayne, L Wickham, W Jin, ...
Journal of Biological Chemistry 279 (47), 48865-48875, 2004
6592004
Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte‐specific low‐density lipoprotein receptor degradation and critical role in mouse liver regeneration
A Zaid, A Roubtsova, R Essalmani, J Marcinkiewicz, A Chamberland, ...
Hepatology 48 (2), 646-654, 2008
3542008
The activation and physiological functions of the proprotein convertases
NG Seidah, G Mayer, A Zaid, E Rousselet, N Nassoury, S Poirier, ...
The international journal of biochemistry & cell biology 40 (6-7), 1111-1125, 2008
3372008
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine PrP
JL Vilotte, S Soulier, R Essalmani, MG Stinnakre, D Vaiman, L Lepourry, ...
Journal of virology 75 (13), 5977-5984, 2001
1972001
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission
V Béringue, O Andréoletti, A Le Dur, R Essalmani, JL Vilotte, C Lacroux, ...
Journal of Neuroscience 27 (26), 6965-6971, 2007
1452007
In vivo evidence that furin from hepatocytes inactivates PCSK9
R Essalmani, D Susan-Resiga, A Chamberland, M Abifadel, ...
Journal of Biological Chemistry 286 (6), 4257-4263, 2011
1422011
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5
D Szumska, G Pieles, R Essalmani, M Bilski, D Mesnard, K Kaur, ...
Genes & development 22 (11), 1465-1477, 2008
1372008
In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate
R Essalmani, A Zaid, J Marcinkiewicz, A Chamberland, A Pasquato, ...
Proceedings of the National Academy of Sciences 105 (15), 5750-5755, 2008
1112008
Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse
R Essalmani, J Hamelin, J Marcinkiewicz, A Chamberland, M Mbikay, ...
Molecular and Cellular Biology 26 (1), 354-361, 2006
982006
Expression of constitutively active guanylate cyclase in cardiomyocytes inhibits the hypertrophic effects of isoproterenol and aortic constriction on mouse hearts
A Zahabi, S Picard, N Fortin, TL Reudelhuber, CF Deschepper
Journal of biological chemistry 278 (48), 47694-47699, 2003
972003
Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice
WC Wetsel, RM Rodriguiz, J Guillemot, E Rousselet, R Essalmani, IH Kim, ...
Proceedings of the National Academy of Sciences 110 (43), 17362-17367, 2013
792013
Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver
X Sun, R Essalmani, R Day, AM Khatib, NG Seidah, A Prat
Neoplasia 14 (12), 1122-IN5, 2012
742012
Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes
MM Hipp, D Shepherd, U Gileadi, MC Aichinger, BM Kessler, ...
Immunity 39 (4), 711-721, 2013
682013
Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events
S Benjannet, YGL Saavedra, J Hamelin, MC Asselin, R Essalmani, ...
Journal of Biological Chemistry 285 (52), 40965-40978, 2010
672010
New in vivo and ex vivo models for the experimental study of sheep scrapie: development and perspectives
H Laude, D Vilette, A Le Dur, F Archer, S Soulier, N Besnard, R Essalmani, ...
Comptes rendus biologies 325 (1), 49-57, 2002
652002
Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin
J Guillemot, M Canuel, R Essalmani, A Prat, NG Seidah
Hepatology 57 (6), 2514-2524, 2013
632013
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10
D Susan-Resiga, R Essalmani, J Hamelin, MC Asselin, S Benjannet, ...
Journal of Biological Chemistry 286 (26), 22785-22794, 2011
612011
The role of presenilin-1 in the γ-secretase cleavage of the amyloid precursor protein of Alzheimer's disease
JN Octave, R Essalmani, B Tasiaux, J Menager, C Czech, L Mercken
Journal of Biological Chemistry 275 (3), 1525-1528, 2000
492000
PCSK9 deficiency unmasks a sex-and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice [S]
A Roubtsova, A Chamberland, J Marcinkiewicz, R Essalmani, A Fazel, ...
Journal of lipid research 56 (11), 2133-2142, 2015
452015
Amyloid precursor-like protein 2 and sortilin do not regulate the PCSK9 convertase-mediated low density lipoprotein receptor degradation but interact with each other
C Butkinaree, M Canuel, R Essalmani, S Poirier, S Benjannet, MC Asselin, ...
Journal of Biological Chemistry 290 (30), 18609-18620, 2015
452015
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