Huilin Huang
Huilin Huang
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FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase
Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ...
Cancer cell 31 (1), 127-141, 2017
6872017
Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ...
Nature cell biology 20 (3), 285-295, 2018
6542018
R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling
R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ...
Cell 172 (1-2), 90-105. e23, 2018
4262018
METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification
H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ...
Cell stem cell 22 (2), 191-205. e9, 2018
4072018
RNA N 6-methyladenosine modification in cancers: current status and perspectives
X Deng, R Su, H Weng, H Huang, Z Li, J Chen
Cell research 28 (5), 507-517, 2018
2382018
Histone H3 trimethylation at lysine 36 guides m 6 A RNA modification co-transcriptionally
H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ...
Nature 567 (7748), 414-419, 2019
1992019
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
Y Xu, XD Gao, JH Lee, H Huang, H Tan, J Ahn, LM Reinke, ME Peter, ...
Genes & development 28 (11), 1191-1203, 2014
1792014
High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells
B Du, LM Ma, MB Huang, H Zhou, HL Huang, P Shao, YQ Chen, LH Qu
FEBS letters 584 (4), 811-816, 2010
1792010
m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer
H Huang, H Weng, J Chen
Cancer cell 37 (3), 270-288, 2020
1572020
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner
S Müller, M Glaß, AK Singh, J Haase, N Bley, T Fuchs, M Lederer, A Dahl, ...
Nucleic acids research 47 (1), 375-390, 2019
1132019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer Cell 38 (1), 79-96. e11, 2020
892020
RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF
H Huang, J Zhang, SE Harvey, X Hu, C Cheng
Genes & development 31 (22), 2296-2309, 2017
852017
Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis
HL Huang, HY Weng, LQ Wang, CH Yu, QJ Huang, PP Zhao, JZ Wen, ...
Molecular cancer therapeutics 11 (5), 1155-1165, 2012
742012
Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S
H Weng, H Huang, B Dong, P Zhao, H Zhou, L Qu
Cancer research 74 (16), 4409-4419, 2014
692014
The biogenesis and precise control of RNA m6A methylation
H Huang, H Weng, J Chen
Trends in Genetics 36 (1), 44-52, 2020
642020
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia
C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ...
Cell Stem Cell 27 (1), 64-80. e9, 2020
592020
Attacking c-Myc: targeted and combined therapies for cancer
H Huang, H Weng, H Zhou, L Qu
Current pharmaceutical design 20 (42), 6543-6554, 2014
552014
Translational repression of cyclin D3 by a stable G-quadruplex in its 5′ UTR: implications for cell cycle regulation
HY Weng, HL Huang, PP Zhao, H Zhou, LH Qu
RNA biology 9 (8), 1099-1109, 2012
392012
Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
X Jiang, C Hu, K Ferchen, J Nie, X Cui, CH Chen, L Cheng, Z Zuo, ...
Nature communications 8 (1), 1-13, 2017
352017
RNA modifications in cancer: functions, mechanisms, and therapeutic implications
H Huang, H Weng, X Deng, J Chen
Annual Review of Cancer Biology 4, 221-240, 2020
292020
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Artikelen 1–20