| Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ... Nature cell biology 20 (3), 285-295, 2018 | 1960 | 2018 |
| FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ... Cancer cell 31 (1), 127-141, 2017 | 1258 | 2017 |
| R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1), 90-105. e23, 2018 | 855 | 2018 |
| METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 822 | 2018 |
| m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer H Huang, H Weng, J Chen Cancer cell 37 (3), 270-288, 2020 | 772 | 2020 |
| RNA N6-methyladenosine modification in cancers: current status and perspectives X Deng, R Su, H Weng, H Huang, Z Li, J Chen Cell research 28 (5), 507-517, 2018 | 602 | 2018 |
| Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 495 | 2019 |
| Targeting FTO suppresses cancer stem cell maintenance and immune evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer cell 38 (1), 79-96. e11, 2020 | 444 | 2020 |
| IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner S Müller, M Glaß, AK Singh, J Haase, N Bley, T Fuchs, M Lederer, A Dahl, ... Nucleic acids research 47 (1), 375-390, 2019 | 297 | 2019 |
| RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ... Cell stem cell 27 (1), 64-80. e9, 2020 | 272 | 2020 |
| Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing Y Xu, XD Gao, JH Lee, H Huang, H Tan, J Ahn, LM Reinke, ME Peter, ... Genes & development 28 (11), 1191-1203, 2014 | 227 | 2014 |
| The biogenesis and precise control of RNA m6A methylation H Huang, H Weng, J Chen Trends in Genetics 36 (1), 44-52, 2020 | 213 | 2020 |
| High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells B Du, LM Ma, MB Huang, H Zhou, HL Huang, P Shao, YQ Chen, LH Qu FEBS letters 584 (4), 811-816, 2010 | 205 | 2010 |
| RNA G-quadruplex secondary structure promotes alternative splicing via the RNA-binding protein hnRNPF H Huang, J Zhang, SE Harvey, X Hu, C Cheng Genes & development 31 (22), 2296-2309, 2017 | 159 | 2017 |
| Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis HL Huang, HY Weng, LQ Wang, CH Yu, QJ Huang, PP Zhao, JZ Wen, ... Molecular cancer therapeutics 11 (5), 1155-1165, 2012 | 104 | 2012 |
| Attacking c-Myc: targeted and combined therapies for cancer H Huang, H Weng, H Zhou, L Qu Current pharmaceutical design 20 (42), 6543-6554, 2014 | 86 | 2014 |
| Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S H Weng, H Huang, B Dong, P Zhao, H Zhou, L Qu Cancer research 74 (16), 4409-4419, 2014 | 78 | 2014 |
| The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia H Weng, F Huang, Z Yu, Z Chen, E Prince, Y Kang, K Zhou, W Li, J Hu, ... Cancer Cell 40 (12), 1566-1582. e10, 2022 | 71 | 2022 |
| RNA modifications in cancer: functions, mechanisms, and therapeutic implications H Huang, H Weng, X Deng, J Chen Annual Review of Cancer Biology 4, 221-240, 2020 | 71 | 2020 |
| N (6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay TL Xia, X Li, X Wang, YJ Zhu, H Zhang, W Cheng, ML Chen, Y Ye, Y Li, ... EMBO reports 22 (4), e50128, 2021 | 66 | 2021 |
