| Allostery in its many disguises: from theory to applications SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ... Structure 27 (4), 566-578, 2019 | 300 | 2019 |
| TRAPP webserver: predicting protein binding site flexibility and detecting transient binding pockets A Stank, DB Kokh, M Horn, E Sizikova, R Neil, J Panecka, S Richter, ... Nucleic acids research 45 (W1), W325-W330, 2017 | 52 | 2017 |
| Interplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study J Panecka, C Mura, J Trylska PloS one 9 (11), e111811, 2014 | 27 | 2014 |
| Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors J Panecka-Hofman, I Pöhner, F Spyrakis, T Zeppelin, F Di Pisa, LD Iacono, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (12), 3215-3230, 2017 | 25 | 2017 |
| Molecular dynamics of potential rRNA binders: single-stranded nucleic acids and some analogues J Panecka, C Mura, J Trylska The journal of physical chemistry B 115 (3), 532-546, 2011 | 24 | 2011 |
| Accelerating drug discovery efforts for trypanosomatidic infections using an integrated transnational academic drug discovery platform CB Moraes, G Witt, M Kuzikov, B Ellinger, T Calogeropoulou, KC Prousis, ... SLAS DISCOVERY: Advancing Life Sciences R&D 24 (3), 346-361, 2019 | 22 | 2019 |
| Role of S-turn2 in the structure, dynamics, and function of mitochondrial ribosomal A-site. A bioinformatics and molecular dynamics simulation study J Panecka, M Havrila, K Reblova, J Sponer, J Trylska The Journal of Physical Chemistry B 118 (24), 6687-6701, 2014 | 13 | 2014 |
| Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 I Pöhner, A Quotadamo, J Panecka-Hofman, R Luciani, M Santucci, ... Journal of Medicinal Chemistry 65 (13), 9011–9033, 2022 | 11 | 2022 |
| Conformational dynamics of bacterial and human cytoplasmic models of the ribosomal A-site J Panecka, J Šponer, J Trylska Biochimie 112, 96-110, 2015 | 11 | 2015 |
| Application of a simple quantum chemical approach to ligand fragment scoring for Trypanosoma brucei pteridine reductase 1 inhibition W Jedwabny, J Panecka-Hofman, E Dyguda-Kazimierowicz, RC Wade, ... Journal of Computer-Aided Molecular Design 31, 715-728, 2017 | 10 | 2017 |
| An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration M Tanvir Rahman, M Kristian Koski, J Panecka-Hofman, W Schmitz, ... Nature Communications 14 (1), 619, 2023 | 8 | 2023 |
| Anti-trypanosomatid structure-based drug design–lessons learned from targeting the folate pathway J Panecka-Hofman, I Poehner, RC Wade Expert Opinion on Drug Discovery 17 (9), 1029-1045, 2022 | 5 | 2022 |
| Hits and lead discovery in the identification of new drugs against the trypanosomatidic infections T Calogeropoulou, GE Magoulas, I Pöhner, J Panecka-Hofman, ... Medicinal Chemistry of Neglected and Tropical Diseases, 185-231, 2019 | 4 | 2019 |
| Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design J Panecka-Hofman, I Poehner European Biophysics Journal 52 (6), 521-532, 2023 | 2 | 2023 |
| Molecular dynamics techniques in the studies of the bacterial ribosome J Panecka, J Trylska AIP Conference Proceedings 1456 (1), 207-214, 2012 | 2 | 2012 |
| Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism D Kubacka, M Kozarski, MR Baranowski, R Wojcik, J Panecka-Hofman, ... Pharmaceuticals 15 (5), 554, 2022 | 1 | 2022 |
| Exploring target flexibility for drug design D Kokh, A Stank, M Horn, E Sizikova, R Neil, J Panecka, S Richter, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
| Mutations in the Bacterial Ribosomal Protein S12 Influence Aminoglycoside Antibiotic And Ribosome Dynamics J Panecka, C Mura, J Trylska PROTEIN SCIENCE 23, 241-242, 2014 | | 2014 |
| Comparing the dynamics of the bacterial and human ribosomal A-site J Panecka, K Reblova, M Kara, M Zacharias, J Sponer, J Trylska ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
| Targeting bacterial ribosomal RNA [p][p][p][p] J Trylska, J Romanowska, T Witula, S Thoduka, Z Dabrowska, M Jasinski, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
Rebecca WadeHeidelberg Institute for Theoretical Studies and Heidelberg UniversityVerified email at h-its.org
