A semi-synthetic organism with an expanded genetic alphabet DA Malyshev, K Dhami, T Lavergne, T Chen, N Dai, JM Foster, IR Corrêa, ... Nature 509 (7500), 385-388, 2014 | 665 | 2014 |
A semisynthetic organism engineered for the stable expansion of the genetic alphabet Y Zhang, BM Lamb, AW Feldman, AX Zhou, T Lavergne, L Li, ... Proceedings of the National Academy of Sciences 114 (6), 1317-1322, 2017 | 209 | 2017 |
Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet DA Malyshev, K Dhami, HT Quach, T Lavergne, P Ordoukhanian, ... Proceedings of the National Academy of Sciences 109 (30), 12005-12010, 2012 | 175 | 2012 |
Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications L Li, M Degardin, T Lavergne, DA Malyshev, K Dhami, P Ordoukhanian, ... Journal of the American Chemical Society 136 (3), 826-829, 2014 | 174 | 2014 |
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry K Betz, DA Malyshev, T Lavergne, W Welte, K Diederichs, TJ Dwyer, ... Nature chemical biology 8 (7), 612-614, 2012 | 153 | 2012 |
Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs YJ Seo, DA Malyshev, T Lavergne, P Ordoukhanian, FE Romesberg Journal of the American Chemical Society 133 (49), 19878-19888, 2011 | 110 | 2011 |
A Base‐Labile Group for 2′‐OH Protection of Ribonucleosides: A Major Challenge for RNA Synthesis T Lavergne, JR Bertrand, JJ Vasseur, F Debart Chemistry-A European Journal 14 (30), 9135-9138, 2008 | 110 | 2008 |
Structural insights into DNA replication without hydrogen bonds K Betz, DA Malyshev, T Lavergne, W Welte, K Diederichs, FE Romesberg, ... Journal of the American Chemical Society 135 (49), 18637-18643, 2013 | 86 | 2013 |
Efficient solid-phase chemical synthesis of 5′-triphosphates of DNA, RNA, and their analogues I Zlatev, T Lavergne, F Debart, JJ Vasseur, M Manoharan, F Morvan Organic letters 12 (10), 2190-2193, 2010 | 69 | 2010 |
Chemical RNA synthesis method F Debart, J Vasseur, T Lavergne US Patent 8,536,318, 2013 | 56 | 2013 |
Major groove substituents and polymerase recognition of a class of predominantly hydrophobic unnatural base pairs T Lavergne, MDA Malyshev, FE Romesberg Chemistry (Weinheim an der Bergstrasse, Germany) 18 (4), 1231, 2012 | 54 | 2012 |
Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair T Lavergne, M Degardin, DA Malyshev, HT Quach, K Dhami, ... Journal of the American Chemical Society 135 (14), 5408-5419, 2013 | 49 | 2013 |
FRET characterization of complex conformational changes in a large 16S ribosomal RNA fragment site-specifically labeled using unnatural base pairs T Lavergne, R Lamichhane, DA Malyshev, Z Li, L Li, E Sperling, ... ACS chemical biology 11 (5), 1347-1353, 2016 | 47 | 2016 |
New Ruthenium‐Based Probes for Selective G‐Quadruplex Targeting G Piraux, L Bar, M Abraham, T Lavergne, H Jamet, J Dejeu, L Marcélis, ... Chemistry–A European Journal 23 (49), 11872-11880, 2017 | 38 | 2017 |
Synthesis and Preliminary Evaluation of pro-RNA 2′-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay T Lavergne, C Baraguey, C Dupouy, N Parey, W Wuensche, G Sczakiel, ... The Journal of organic chemistry 76 (14), 5719-5731, 2011 | 36 | 2011 |
Template‐Mediated Stabilization of a DNA G‐Quadruplex formed in the HIV‐1 Promoter and Comparative Binding Studies L Bonnat, L Bar, B Génnaro, H Bonnet, O Jarjayes, F Thomas, J Dejeu, ... Chemistry-A European Journal 23 (23), 5602-5613, 2017 | 35 | 2017 |
Assessment of new 2′-O-acetalester protecting groups for regular RNA synthesis and original 2′-modified proRNA AR Martin, T Lavergne, JJ Vasseur, F Debart Bioorganic & medicinal chemistry letters 19 (15), 4046-4049, 2009 | 28 | 2009 |
Efficient Inhibition of Telomerase by Nickel–Salophen Complexes L Lecarme, E Prado, A De Rache, ML Nicolau‐Travers, G Gellon, J Dejeu, ... ChemMedChem 11 (11), 1133-1136, 2016 | 27 | 2016 |
Construction of anti-parallel G-quadruplexes through sequential templated click R Bonnet, T Lavergne, B Gennaro, N Spinelli, E Defrancq Chemical Communications 51 (23), 4850-4853, 2015 | 27 | 2015 |
Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands L Bonnat, M Dautriche, T Saidi, J Revol-Cavalier, J Dejeu, E Defrancq, ... Organic & biomolecular chemistry 17 (38), 8726-8736, 2019 | 21 | 2019 |