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Akihito Otsuki
Akihito Otsuki
Geverifieerd e-mailadres voor tohoku.ac.jp
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A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv (3)(q21; q26) by activating EVI1 expression
H Yamazaki, M Suzuki, A Otsuki, R Shimizu, EH Bresnick, JD Engel, ...
Cancer cell 25 (4), 415-427, 2014
2572014
Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation
K Tsuchida, T Tsujita, M Hayashi, A Ojima, N Keleku-Lukwete, F Katsuoka, ...
Free Radical Biology and Medicine 103, 236-247, 2017
1382017
3.5 KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome
S Tadaka, F Katsuoka, M Ueki, K Kojima, S Makino, S Saito, A Otsuki, ...
Human Genome Variation 6 (1), 28, 2019
1272019
jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population
S Tadaka, E Hishinuma, S Komaki, IN Motoike, J Kawashima, D Saigusa, ...
Nucleic acids research 49 (D1), D536-D544, 2021
1172021
Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation
N Keleku-Lukwete, M Suzuki, A Otsuki, K Tsuchida, S Katayama, ...
Proceedings of the National Academy of Sciences 112 (39), 12169-12174, 2015
1022015
Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection
A Otsuki, M Suzuki, F Katsuoka, K Tsuchida, H Suda, M Morita, R Shimizu, ...
Free Radical Biology and Medicine 91, 45-57, 2016
642016
Overview of redox regulation by Keap1–Nrf2 system in toxicology and cancer
M Suzuki, A Otsuki, N Keleku-Lukwete, M Yamamoto
Current Opinion in Toxicology 1, 29-36, 2016
622016
Cis-element architecture of Nrf2–sMaf heterodimer binding sites and its relation to diseases
A Otsuki, M Yamamoto
Archives of pharmacal research 43 (3), 275-285, 2020
492020
Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference
J Takayama, S Tadaka, K Yano, F Katsuoka, C Gocho, T Funayama, ...
Nature communications 12 (1), 1-14, 2021
432021
GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis
S Katayama, M Suzuki, A Yamaoka, N Keleku-Lukwete, F Katsuoka, ...
Blood, The Journal of the American Society of Hematology 130 (7), 908-919, 2017
432017
Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare
J Yasuda, K Kinoshita, F Katsuoka, I Danjoh, M Sakurai-Yageta, ...
The journal of biochemistry 165 (2), 139-158, 2019
412019
Nrf2 contributes to the weight gain of mice during space travel
T Suzuki, A Uruno, A Yumoto, K Taguchi, M Suzuki, N Harada, R Ryoke, ...
Communications biology 3 (1), 1-14, 2020
312020
Direct and specific functional evaluation of the Nrf2 and MafG heterodimer by introducing a tethered dimer into small Maf-deficient cells
F Katsuoka, A Otsuki, M Takahashi, S Ito, M Yamamoto
Molecular and cellular biology 39 (20), e00273-19, 2019
282019
Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs
M Sakurai-Yageta, K Kumada, C Gocho, S Makino, A Uruno, S Tadaka, ...
The Journal of Biochemistry 170 (3), 399-410, 2021
212021
Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs
M Sakurai-Yageta, K Kumada, C Gocho, S Makino, A Uruno, S Tadaka, ...
Journal of Biochemistry 170 (3), 399-410, 2021
212021
Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice
N Keleku-Lukwete, M Suzuki, H Panda, A Otsuki, F Katsuoka, R Saito, ...
Blood advances 3 (8), 1285-1297, 2019
192019
The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation In Vivo
A Kuga, K Tsuchida, H Panda, M Horiuchi, A Otsuki, K Taguchi, ...
Molecular and cellular biology 42 (7), e00563-21, 2022
152022
Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect
T Moriguchi, L Yu, A Otsuki, K Ainoya, KC Lim, M Yamamoto, JD Engel
Molecular and cellular biology 36 (17), 2272-2281, 2016
142016
Derepression of the DNA Methylation Machinery of the Gata1 Gene Triggers the Differentiation Cue for Erythropoiesis
L Yu, J Takai, A Otsuki, F Katsuoka, M Suzuki, S Katayama, M Nezu, ...
Molecular and cellular biology 37 (8), e00592-16, 2017
122017
Target Gene Diversity of the Nrf1-MafG Transcription Factor Revealed by a Tethered Heterodimer
F Katsuoka, A Otsuki, N Hatanaka, H Okuyama, M Yamamoto
Molecular and cellular biology 42 (3), e00520-21, 2022
102022
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Artikelen 1–20