| The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity CJ Gloeckner, N Kinkl, A Schumacher, RJ Braun, E O'Neill, T Meitinger, ... Human molecular genetics 15 (2), 223-232, 2006 | 563 | 2006 |
| LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool G Piccoli, SB Condliffe, M Bauer, F Giesert, K Boldt, S De Astis, A Meixner, ... Journal of Neuroscience 31 (6), 2225-2237, 2011 | 332 | 2011 |
| A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes CJ Gloeckner, K Boldt, A Schumacher, R Roepman, M Ueffing Proteomics 7 (23), 4228-4234, 2007 | 278 | 2007 |
| An organelle-specific protein landscape identifies novel diseases and molecular mechanisms K Boldt, J Van Reeuwijk, Q Lu, K Koutroumpas, TMT Nguyen, Y Texier, ... Nature communications 7 (1), 11491, 2016 | 243 | 2016 |
| The Parkinson disease‐associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro CJ Gloeckner, A Schumacher, K Boldt, M Ueffing Journal of neurochemistry 109 (4), 959-968, 2009 | 234 | 2009 |
| Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ... Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016 | 157 | 2016 |
| A QUICK screen for Lrrk2 interaction partners–leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics A Meixner, K Boldt, M Van Troys, M Askenazi, CJ Gloeckner, M Bauer, ... Molecular & Cellular Proteomics 10 (1), 2011 | 155 | 2011 |
| ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations E Kortvely, SM Hauck, G Duetsch, CJ Gloeckner, E Kremmer, ... Investigative ophthalmology & visual science 51 (1), 79-88, 2010 | 154 | 2010 |
| Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2 CJ Gloeckner, K Boldt, F Von Zweydorf, S Helm, L Wiesent, H Sarioglu, ... Journal of proteome research 9 (4), 1738-1745, 2010 | 151 | 2010 |
| Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3 K Muda, D Bertinetti, F Gesellchen, JS Hermann, F von Zweydorf, ... Proceedings of the National Academy of Sciences of the United States of America, 2013 | 143 | 2013 |
| Type IV procollagen missense mutations associated with defects of the eye, vascular stability, the brain, kidney function and embryonic or postnatal viability in the mouse, Mus … J Favor, CJ Gloeckner, D Janik, M Klempt, A Neuhäuser-Klaus, ... Genetics 175 (2), 725-736, 2007 | 137 | 2007 |
| Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice K Boldt, DA Mans, J Won, J Van Reeuwijk, A Vogt, N Kinkl, SJF Letteboer, ... The Journal of clinical investigation 121 (6), 2169-2180, 2011 | 131 | 2011 |
| Modified transposases for improved insertion sequence bias and increased DNA input tolerance C Gloeckner, KIA Amirali, E Bomati, M He, HL Grunenwald, S Kuersten, ... US Patent 9,790,476, 2017 | 130 | 2017 |
| Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain G Piccoli, F Onofri, MD Cirnaru, CJO Kaiser, P Jagtap, A Kastenmüller, ... Molecular and cellular biology 34 (12), 2147-2161, 2014 | 121 | 2014 |
| Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy D Sibbing, A Pfeufer, T Perisic, AM Mannes, K Fritz-Wolf, S Unwin, ... European heart journal 32 (9), 1121-1133, 2011 | 109 | 2011 |
| Tandem affinity purification of protein complexes from mammalian cells by the Strep/FLAG (SF)-TAP tag CJ Gloeckner, K Boldt, A Schumacher, M Ueffing Proteomics: Methods and Protocols, 359-372, 2009 | 100 | 2009 |
| LRRK2 transport is regulated by its novel interacting partner Rab32 D Waschbüsch, H Michels, S Strassheim, E Ossendorf, D Kessler, ... PloS one 9 (10), e111632, 2014 | 97 | 2014 |
| Strep/FLAG tandem affinity purification (SF‐TAP) to study protein interactions CJ Gloeckner, K Boldt, M Ueffing Current Protocols in Protein Science 57 (1), 19.20. 1-19.20. 19, 2009 | 93 | 2009 |
| ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2 K Haebig, CJ Gloeckner, MG Miralles, F Gillardon, C Schulte, O Riess, ... PloS one 5 (10), e13762, 2010 | 82 | 2010 |
| The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase KLM Coene, DA Mans, K Boldt, CJ Gloeckner, J van Reeuwijk, E Bolat, ... Human molecular genetics 20 (18), 3592-3605, 2011 | 80 | 2011 |
