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Lena Ho
Lena Ho
Duke NUS Medical School
Verified email at ho-lab.org - Homepage
Title
Cited by
Cited by
Year
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
C Kadoch, DC Hargreaves, C Hodges, L Elias, L Ho, J Ranish, ...
Nature genetics 45 (6), 592-601, 2013
13692013
Chromatin remodelling during development
L Ho, GR Crabtree
Nature 463 (7280), 474-484, 2010
12952010
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
H Ji, LIR Ehrlich, J Seita, P Murakami, A Doi, P Lindau, H Lee, MJ Aryee, ...
Nature 467 (7313), 338-342, 2010
7442010
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
L Ho, JL Ronan, J Wu, BT Staahl, L Chen, A Kuo, J Lessard, ...
Proceedings of the National Academy of Sciences 106 (13), 5181-5186, 2009
6562009
ELABELA: a hormone essential for heart development signals via the apelin receptor
SC Chng, L Ho, J Tian, B Reversade
Developmental cell 27 (6), 672-680, 2013
4952013
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
L Ho, R Jothi, JL Ronan, K Cui, K Zhao, GR Crabtree
Proceedings of the National Academy of Sciences 106 (13), 5187-5191, 2009
4892009
esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
L Ho, EL Miller, JL Ronan, WQ Ho, R Jothi, GR Crabtree
Nature cell biology 13 (8), 903-913, 2011
2992011
ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice
L Ho, M Van Dijk, STJ Chye, DM Messerschmidt, SC Chng, S Ong, LK Yi, ...
Science 357 (6352), 707-713, 2017
2212017
ELABELA is an endogenous growth factor that sustains hESC self-renewal via the PI3K/AKT pathway
L Ho, SYX Tan, S Wee, Y Wu, SJC Tan, NB Ramakrishna, SC Chng, ...
Cell stem cell 17 (4), 435-447, 2015
1762015
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage
T Sato, C Sato, A Kadowaki, H Watanabe, L Ho, J Ishida, T Yamaguchi, ...
Cardiovascular research 113 (7), 760-769, 2017
1392017
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
M Buscarlet, V Krasteva, L Ho, C Simon, J Hébert, B Wilhelm, ...
Blood, The Journal of the American Society of Hematology 123 (11), 1720-1728, 2014
1202014
Brg1 modulates enhancer activation in mesoderm lineage commitment
JM Alexander, SK Hota, D He, S Thomas, L Ho, LA Pennacchio, ...
Development 142 (8), 1418-1430, 2015
1142015
Alternative progenitor cells compensate to rebuild the coronary vasculature in Elabela-and Apj-deficient hearts
B Sharma, L Ho, GH Ford, HI Chen, AB Goldstone, YJ Woo, ...
Developmental Cell 42 (6), 655-666. e3, 2017
1032017
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
S Zhang, B Reljić, C Liang, B Kerouanton, JC Francisco, JH Peh, C Mary, ...
Nature communications 11 (1), 1312, 2020
962020
C5orf42 is the major gene responsible for OFD syndrome type VI
E Lopez, C Thauvin-Robinet, B Reversade, NE Khartoufi, L Devisme, ...
Human genetics 133, 367-377, 2014
872014
Calcineurin sets the bandwidth for discrimination of signals during thymocyte development
EM Gallo, MM Winslow, K Canté-Barrett, AN Radermacher, L Ho, ...
Nature 450 (7170), 731-735, 2007
782007
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ...
Nature communications 12 (1), 2130, 2021
662021
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ...
Science 377 (6603), 328-335, 2022
642022
A high-resolution map of human RNA translation
SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ...
Molecular cell 82 (15), 2885-2899. e8, 2022
432022
The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development
AR Deshwar, SC Chng, L Ho, B Reversade, IC Scott
Elife 5, e13758, 2016
342016
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