| A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat L Kazak, ET Chouchani, MP Jedrychowski, BK Erickson, K Shinoda, ... Cell 163 (3), 643-655, 2015 | 613 | 2015 |
| Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia S Kir, JP White, S Kleiner, L Kazak, P Cohen, VE Baracos, ... Nature 513 (7516), 100-104, 2014 | 560 | 2014 |
| New advances in adaptive thermogenesis: UCP1 and beyond ET Chouchani, L Kazak, BM Spiegelman Cell metabolism 29 (1), 27-37, 2019 | 458 | 2019 |
| Minimizing the damage: repair pathways keep mitochondrial DNA intact L Kazak, A Reyes, IJ Holt Nature reviews Molecular cell biology 13 (10), 659-671, 2012 | 415 | 2012 |
| Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1 ET Chouchani, L Kazak, MP Jedrychowski, GZ Lu, BK Erickson, J Szpyt, ... Nature 532 (7597), 112-116, 2016 | 375 | 2016 |
| Accumulation of succinate controls activation of adipose tissue thermogenesis EL Mills, KA Pierce, MP Jedrychowski, R Garrity, S Winther, S Vidoni, ... Nature 560 (7716), 102-106, 2018 | 349 | 2018 |
| Fat cells directly sense temperature to activate thermogenesis L Ye, J Wu, P Cohen, L Kazak, MJ Khandekar, MP Jedrychowski, X Zeng, ... Proceedings of the National Academy of Sciences 110 (30), 12480-12485, 2013 | 257 | 2013 |
| IRF4 is a key thermogenic transcriptional partner of PGC-1α X Kong, A Banks, T Liu, L Kazak, RR Rao, P Cohen, X Wang, S Yu, JC Lo, ... Cell 158 (1), 69-83, 2014 | 246 | 2014 |
| Genetic depletion of adipocyte creatine metabolism inhibits diet-induced thermogenesis and drives obesity L Kazak, ET Chouchani, GZ Lu, MP Jedrychowski, CJ Bare, AI Mina, ... Cell metabolism 26 (4), 660-671. e3, 2017 | 233 | 2017 |
| mTOR as a central regulator of lifespan and aging D Papadopoli, K Boulay, L Kazak, M Pollak, FA Mallette, I Topisirovic, ... F1000Research 8, 2019 | 221 | 2019 |
| Mitochondrial patch clamp of beige adipocytes reveals UCP1-positive and UCP1-negative cells both exhibiting futile creatine cycling AM Bertholet, L Kazak, ET Chouchani, MG Bogaczyńska, I Paranjpe, ... Cell metabolism 25 (4), 811-822. e4, 2017 | 196 | 2017 |
| H+ transport is an integral function of the mitochondrial ADP/ATP carrier AM Bertholet, ET Chouchani, L Kazak, A Angelin, A Fedorenko, JZ Long, ... Nature 571 (7766), 515-520, 2019 | 163 | 2019 |
| UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction L Kazak, ET Chouchani, IG Stavrovskaya, GZ Lu, MP Jedrychowski, ... Proceedings of the National Academy of Sciences 114 (30), 7981-7986, 2017 | 146 | 2017 |
| IRF3 promotes adipose inflammation and insulin resistance and represses browning M Kumari, X Wang, L Lantier, A Lyubetskaya, J Eguchi, S Kang, D Tenen, ... The Journal of clinical investigation 126 (8), 2839-2854, 2016 | 146 | 2016 |
| Brown adipose tissue controls skeletal muscle function via the secretion of myostatin X Kong, T Yao, P Zhou, L Kazak, D Tenen, A Lyubetskaya, BA Dawes, ... Cell metabolism 28 (4), 631-643. e3, 2018 | 133 | 2018 |
| Mitochondrial DNA replication proceeds via a ‘bootlace’mechanism involving the incorporation of processed transcripts A Reyes, L Kazak, SR Wood, T Yasukawa, HT Jacobs, IJ Holt Nucleic acids research 41 (11), 5837-5850, 2013 | 129 | 2013 |
| Actin and myosin contribute to mammalian mitochondrial DNA maintenance A Reyes, J He, CC Mao, LJ Bailey, M Di Re, H Sembongi, L Kazak, ... Nucleic acids research 39 (12), 5098-5108, 2011 | 106 | 2011 |
| Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity L Kazak, JF Rahbani, B Samborska, GZ Lu, MP Jedrychowski, M Lajoie, ... Nature metabolism 1 (3), 360-370, 2019 | 105 | 2019 |
| UCP1-independent thermogenesis A Roesler, L Kazak Biochemical Journal 477 (3), 709-725, 2020 | 95 | 2020 |
| Human C4orf14 interacts with the mitochondrial nucleoid and is involved in the biogenesis of the small mitochondrial ribosomal subunit J He, HM Cooper, A Reyes, M Di Re, L Kazak, SR Wood, CC Mao, ... Nucleic acids research 40 (13), 6097-6108, 2012 | 95 | 2012 |
Bruce M. SpiegelmanStanley J. Korsmeyer Professor, Harvard Medical School and Dana-Farber Cancer InstituteVerified email at dfci.harvard.edu
