Andreas Herrlich MD PhD  Associate Professor of Medicine
Andreas Herrlich MD PhD Associate Professor of Medicine
Washington University School of Medicine in St. Louis
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Signal characteristics of G protein‐transactivated EGF receptor
H Daub, C Wallasch, A Lankenau, A Herrlich, A Ullrich
The EMBO journal 16 (23), 7032-7044, 1997
7811997
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
A Herrlich, H Daub, A Knebel, P Herrlich, A Ullrich, G Schultz, ...
Proceedings of the National Academy of Sciences 95 (15), 8985-8990, 1998
1791998
Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C
A Herrlich, B Kühn, R Grosse, A Schmid, G Schultz, T Gudermann
Journal of Biological Chemistry 271 (28), 16764-16772, 1996
1731996
Gonadotropin-releasing Hormone Receptor Initiates Multiple Signaling Pathways by Exclusively Coupling to Gq/11Proteins
P Muhn, R Grosse, A Schmid, T Schöneberg, A Herrlich, G Schultz, ...
Journal of Biological Chemistry 275 (13), 9193-9200, 2000
1712000
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities
MA Miller, L Barkal, K Jeng, A Herrlich, M Moss, LG Griffith, ...
Integrative Biology 3 (4), 422-438, 2011
962011
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways
M Dang, N Armbruster, MA Miller, E Cermeno, M Hartmann, GW Bell, ...
Proceedings of the National Academy of Sciences 110 (24), 9776-9781, 2013
802013
Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone
R Grosse, S Roelle, A Herrlich, J Höhn, T Gudermann
Journal of Biological Chemistry 275 (16), 12251-12260, 2000
792000
Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone
R Grosse, S Roelle, A Herrlich, J Höhn, T Gudermann
Journal of Biological Chemistry 275 (16), 12251-12260, 2000
792000
ADAM17 substrate release in proximal tubule drives kidney fibrosis
E Kefaloyianni, ML Muthu, J Kaeppler, X Sun, V Sabbisetti, A Chalaris, ...
JCI insight 1 (13), 2016
742016
Who decides when to cleave an ectodomain?
M Hartmann, A Herrlich, P Herrlich
Trends in biochemical sciences 38 (3), 111-120, 2013
642013
PI3k α and STAT 1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization
M Mounayar, E Kefaloyianni, B Smith, Z Solhjou, OH Maarouf, J Azzi, ...
Stem cells 33 (6), 1892-1901, 2015
532015
Epidermal growth factor (EGF) ligand release by substrate-specific a disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on …
M Dang, K Dubbin, A D'Aiello, M Hartmann, H Lodish, A Herrlich
Journal of Biological Chemistry 286 (20), 17704-17713, 2011
462011
Ectodomain cleavage of the EGF ligands HB‐EGF, neuregulin1‐β, and TGF‐α is specifically triggered by different stimuli and involves different PKC isoenzymes
A Herrlich, E Klinman, J Fu, C Sadegh, H Lodish
The FASEB Journal 22 (12), 4281-4295, 2008
412008
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
M Chang-Panesso, FF Kadyrov, M Lalli, H Wu, S Ikeda, E Kefaloyianni, ...
The Journal of clinical investigation 129 (12), 5501-5517, 2019
402019
Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization*♦
M Hartmann, LM Parra, A Ruschel, C Lindner, H Morrison, A Herrlich, ...
Journal of Biological Chemistry 290 (28), 17041-17054, 2015
372015
Distinct intracellular domain substrate modifications selectively regulate ectodomain cleavage of NRG1 or CD44
LM Parra, M Hartmann, S Schubach, Y Li, P Herrlich, A Herrlich
Molecular and cellular biology 35 (19), 3381-3395, 2015
352015
Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC
K Zhang, L Jones, S Lim, CA Maher, D Adkins, J Lewis, RJ Kimple, ...
Oncotarget 5 (19), 9281, 2014
282014
Tumor suppressor NF2 blocks cellular migration by inhibiting ectodomain cleavage of CD44
M Hartmann, LM Parra, A Ruschel, S Böhme, Y Li, H Morrison, A Herrlich, ...
Molecular cancer research 13 (5), 879-890, 2015
252015
Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction
A Herrlich, V Leitch, LS King
Proceedings of the National Academy of Sciences 101 (44), 15799-15804, 2004
212004
Proximal Tubule–Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis
E Kefaloyianni, MRK Raja, J Schumacher, ML Muthu, V Krishnadoss, ...
Journal of the American Society of Nephrology 30 (12), 2370-2383, 2019
142019
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Artikelen 1–20