Distinct subcellular changes in proteasome activity and linkage-specific protein polyubiquitination in the amygdala during the consolidation and reconsolidation of a fear memory SA Orsi, RK Devulapalli, JL Nelsen, T McFadden, R Surineni, TJ Jarome Neurobiology of learning and memory 157, 1-11, 2019 | 31 | 2019 |
Ubiquitination of histone H2B by proteasome subunit RPT6 controls histone methylation chromatin dynamics during memory formation TJ Jarome, GA Perez, WM Webb, KM Hatch, S Navabpour, M Musaus, ... Biological psychiatry 89 (12), 1176-1187, 2021 | 28 | 2021 |
Males and females differ in the regulation and engagement of, but not requirement for, protein degradation in the amygdala during fear memory formation R Devulapalli, N Jones, K Farrell, M Musaus, H Kugler, T McFadden, ... Neurobiology of learning and memory 180, 107404, 2021 | 27 | 2021 |
DNA double-strand breaks are a critical regulator of fear memory reconsolidation S Navabpour, J Rogers, T McFadden, TJ Jarome International Journal of Molecular Sciences 21 (23), 8995, 2020 | 19 | 2020 |
Males and females differ in the subcellular and brain region dependent regulation of proteasome activity by CaMKII and protein kinase A RK Devulapalli, JL Nelsen, SA Orsi, T McFadden, S Navabpour, N Jones, ... Neuroscience 418, 1-14, 2019 | 15 | 2019 |
Dysregulation of protein degradation in the hippocampus is associated with impaired spatial memory during the development of obesity T McFadden, M Musaus, JL Nelsen, K Martin, N Jones, P Smith, H Kugler, ... Behavioural brain research 393, 112787, 2020 | 11 | 2020 |
Quantifying subcellular ubiquitin-proteasome activity in the rodent brain T McFadden, RK Devulapalli, TJ Jarome JoVE (Journal of Visualized Experiments), e59695, 2019 | 8 | 2019 |
Short-term exposure to an obesogenic diet causes dynamic dysregulation of proteasome-mediated protein degradation in the hypothalamus of female rats T McFadden, K Farrell, K Martin, M Musaus, TJ Jarome Nutritional Neuroscience 26 (4), 290-302, 2023 | 3 | 2023 |
Neuronal and astrocytic protein degradation are critical for fear memory formation K Farrell, T McFadden, TJ Jarome Learning & Memory 30 (3), 70-73, 2023 | 3 | 2023 |
Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity T McFadden, N Gaito, I Carucci, E Fletchall, K Farrell, TJ Jarome Plos one 18 (4), e0284286, 2023 | 2 | 2023 |
Hypothalamic DNA 5-hydroxymethylation levels are altered by diet-induced weight gain during the development of obesity in a sex-specific manner T McFadden, I Carucci, K Farrell, E Fletchall, TJ Jarome Brain Research 1817, 148478, 2023 | 1 | 2023 |
Epigenetic and Ubiquitin-Proteasome Mechanisms of Obesity Development TM McFadden Virginia Tech, 2023 | | 2023 |