Suivre
Dr. Isabelle Plo
Dr. Isabelle Plo
INSERM
Adresse e-mail validée de gustaveroussy.fr
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Année
Mutation in TET2 in Myeloid Cancers
F Delhommeau, S Dupont, VD Valle, C James, S Trannoy, A Massé, ...
New England Journal of Medicine 360 (22), 2289-2301, 2009
21592009
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
C Quivoron, L Couronné, V Della Valle, CK Lopez, I Plo, O Wagner-Ballon, ...
Cancer cell 20 (1), 25-38, 2011
10042011
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
E Rass, A Grabarz, I Plo, J Gautier, P Bertrand, BS Lopez
Nature structural & molecular biology 16 (8), 819-824, 2009
3782009
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants
I Chachoua, C Pecquet, M El-Khoury, H Nivarthi, RI Albu, C Marty, ...
Blood, The Journal of the American Society of Hematology 127 (10), 1325-1335, 2016
3582016
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis
C Marty, C Pecquet, H Nivarthi, M El-Khoury, I Chachoua, M Tulliez, ...
Blood, The Journal of the American Society of Hematology 127 (10), 1317-1324, 2016
2852016
Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions
I Plo, ZY Liao, JM Barceló, G Kohlhagen, KW Caldecott, M Weinfeld, ...
DNA repair 2 (10), 1087-1100, 2003
2412003
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors
E Pronier, C Almire, H Mokrani, A Vasanthakumar, A Simon, ...
Blood, The Journal of the American Society of Hematology 118 (9), 2551-2555, 2011
2102011
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends
J Guirouilh-Barbat, E Rass, I Plo, P Bertrand, BS Lopez
Proceedings of the National Academy of Sciences 104 (52), 20902-20907, 2007
2102007
Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients
X Cabagnols, F Favale, F Pasquier, K Messaoudi, JP Defour, JC Ianotto, ...
Blood, The Journal of the American Society of Hematology 127 (3), 333-342, 2016
1992016
JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders
I Plo, M Nakatake, L Malivert, JP de Villartay, S Giraudier, JL Villeval, ...
Blood, The Journal of the American Society of Hematology 112 (4), 1402-1412, 2008
1972008
A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression
C Marty, C Lacout, N Droin, JP Le Couédic, V Ribrag, E Solary, ...
Leukemia 27 (11), 2187-2195, 2013
1862013
Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands
I Moraga, G Wernig, S Wilmes, V Gryshkova, CP Richter, WJ Hong, ...
Cell 160 (6), 1196-1208, 2015
1602015
Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies
J Saliba, C Saint-Martin, A Di Stefano, G Lenglet, C Marty, B Keren, ...
Nature genetics 47 (10), 1131-1140, 2015
1512015
JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders
W Vainchenker, E Leroy, L Gilles, C Marty, I Plo, SN Constantinescu
F1000Research 7, 2018
1502018
Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution
X Cabagnols, JP Defour, V Ugo, JC Ianotto, P Mossuz, J Mondet, ...
Leukemia 29 (1), 249-252, 2015
1472015
AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51
I Plo, C Laulier, L Gauthier, F Lebrun, F Calvo, BS Lopez
Cancer research 68 (22), 9404-9412, 2008
1452008
JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms
M Nakatake, B Monte-Mor, N Debili, N Casadevall, V Ribrag, E Solary, ...
Oncogene 31 (10), 1323-1333, 2012
1342012
Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms
C Saint-Martin, G Leroy, F Delhommeau, G Panelatti, S Dupont, C James, ...
Blood, The Journal of the American Society of Hematology 114 (8), 1628-1632, 2009
1342009
Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia
I Antony-Debré, VT Manchev, N Balayn, D Bluteau, C Tomowiak, ...
Blood, The Journal of the American Society of Hematology 125 (6), 930-940, 2015
1162015
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond–like syndrome
C Bellanné-Chantelot, B Schmaltz-Panneau, C Marty, O Fenneteau, ...
Blood, The Journal of the American Society of Hematology 132 (12), 1318-1331, 2018
1012018
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