IL-6 in inflammation, immunity, and disease T Tanaka, M Narazaki, T Kishimoto Cold Spring Harbor perspectives in biology 6 (10), a016295, 2014 | 4393 | 2014 |
Interleukin-6 family of cytokines and gp130 T Kishimoto, S Akira, M Narazaki, T Taga | 1787 | 1995 |
Structure and function of a new STAT-induced STAT inhibitor T Naka, M Narazaki, M Hirata, T Matsumoto, S Minamoto, A Aono, ... Nature 387 (6636), 924-929, 1997 | 1743 | 1997 |
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. M Murakami, M Narazaki, M Hibi, H Yawata, K Yasukawa, M Hamaguchi, ... Proceedings of the National Academy of Sciences 88 (24), 11349-11353, 1991 | 777 | 1991 |
Immunotherapeutic implications of IL-6 blockade for cytokine storm T Tanaka, M Narazaki, T Kishimoto Immunotherapy 8 (8), 959-970, 2016 | 766 | 2016 |
Targeting interleukin-6 signaling in clinic S Kang, T Tanaka, M Narazaki, T Kishimoto Immunity 50 (4), 1007-1023, 2019 | 726 | 2019 |
Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine Y Maeda, T Kurakawa, E Umemoto, D Motooka, Y Ito, K Gotoh, K Hirota, ... Arthritis & rheumatology 68 (11), 2646-2661, 2016 | 582 | 2016 |
Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130 M Narazaki, K Yasukawa, T Saito, Y Ohsugi, H Fukui, Y Koishihara, ... | 576 | 1993 |
Cardiotrophin-1 Activates a Distinct Form of Cardiac Muscle Cell Hypertrophy: ASSEMBLY OF SARCOMERIC UNITS IN SERIES VIA gp130/LEUKEMIA INHIBITORY FACTOR RECEPTOR-DEPENDENT … KC Wollert, T Taga, M Saito, M Narazaki, T Kishimoto, CC Glembotski, ... Journal of Biological Chemistry 271 (16), 9535-9545, 1996 | 485 | 1996 |
Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130. M Narazaki, BA Witthuhn, K Yoshida, O Silvennoinen, K Yasukawa, ... Proceedings of the National Academy of Sciences 91 (6), 2285-2289, 1994 | 382 | 1994 |
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice T Naka, T Matsumoto, M Narazaki, M Fujimoto, Y Morita, Y Ohsawa, ... Proceedings of the National Academy of Sciences 95 (26), 15577-15582, 1998 | 361 | 1998 |
Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling M Narazaki, M Fujimoto, T Matsumoto, Y Morita, H Saito, T Kajita, ... Proceedings of the National Academy of Sciences 95 (22), 13130-13134, 1998 | 337 | 1998 |
Interleukin (IL-6) immunotherapy T Tanaka, M Narazaki, T Kishimoto Cold Spring Harbor perspectives in biology 10 (8), a028456, 2018 | 312 | 2018 |
Therapeutic targeting of the interleukin-6 receptor T Tanaka, M Narazaki, T Kishimoto Annual review of pharmacology and toxicology 52, 199-219, 2012 | 307 | 2012 |
Differential processing of stromal-derived factor-1α and stromal-derived factor-1β explains functional diversity M De La Luz Sierra, F Yang, M Narazaki, O Salvucci, D Davis, ... Blood 103 (7), 2452-2459, 2004 | 289 | 2004 |
Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130. T Taga, M Narazaki, K Yasukawa, T Saito, D Miki, M Hamaguchi, S Davis, ... Proceedings of the National Academy of Sciences 89 (22), 10998-11001, 1992 | 253 | 1992 |
Historical overview of the interleukin-6 family cytokine S Kang, M Narazaki, H Metwally, T Kishimoto Journal of Experimental Medicine 217 (5), 2020 | 237 | 2020 |
The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab Y Shima, Y Kuwahara, H Murota, S Kitaba, M Kawai, T Hirano, J Arimitsu, ... Rheumatology 49 (12), 2408-2412, 2010 | 235 | 2010 |
Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3 S Minamoto, K Ikegame, K Ueno, M Narazaki, T Naka, H Yamamoto, ... Biochemical and biophysical research communications 237 (1), 79-83, 1997 | 229 | 1997 |
SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-γ and IL-4 signaling in vivo T Naka, H Tsutsui, M Fujimoto, Y Kawazoe, H Kohzaki, Y Morita, ... Immunity 14 (5), 535-545, 2001 | 218 | 2001 |