The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins O Rocks, M Gerauer, N Vartak, S Koch, ZP Huang, M Pechlivanis, ... Cell 141 (3), 458-471, 2010 | 496 | 2010 |
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S Günther, PYA Reinke, Y Fernández-García, J Lieske, TJ Lane, HM Ginn, ... Science 372 (6542), 642-646, 2021 | 318 | 2021 |
Multi-endpoint toxicological assessment of polystyrene nano-and microparticles in different biological models in vitro M Hesler, L Aengenheister, B Ellinger, R Drexel, S Straskraba, C Jost, ... Toxicology in Vitro 61, 104610, 2019 | 245 | 2019 |
Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen M Kuzikov, E Costanzi, J Reinshagen, F Esposito, L Vangeel, M Wolf, ... ACS pharmacology & translational science 4 (3), 1096-1110, 2021 | 131 | 2021 |
Synthesis and structure− activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin R Tannert, LG Milroy, B Ellinger, TS Hu, HD Arndt, H Waldmann Journal of the American Chemical Society 132 (9), 3063-3077, 2010 | 128 | 2010 |
Biology-oriented synthesis of a natural-product inspired oxepane collection yields a small-molecule activator of the Wnt-pathway S Basu, B Ellinger, S Rizzo, C Deraeve, M Schürmann, H Preut, HD Arndt, ... Proceedings of the National Academy of Sciences 108 (17), 6805-6810, 2011 | 100 | 2011 |
Antiplasmodial thiostrepton derivatives: proteasome inhibitors with a dual mode of action S Schoof, G Pradel, MN Aminake, B Ellinger, S Baumann, M Potowski, ... Angewandte Chemie International Edition, 3317-3321, 2010 | 100 | 2010 |
Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection B Ellinger, D Bojkova, A Zaliani, J Cinatl, C Claussen, S Westhaus, ... | 71 | 2020 |
Selective chemical imaging of static actin in live cells LG Milroy, S Rizzo, A Calderon, B Ellinger, S Erdmann, J Mondry, ... Journal of the American Chemical Society 134 (20), 8480-8486, 2012 | 69 | 2012 |
A SARS-CoV-2 cytopathicity dataset generated by high-content screening of a large drug repurposing collection B Ellinger, D Bojkova, A Zaliani, J Cinatl, C Claussen, S Westhaus, ... Scientific data 8 (1), 70, 2021 | 68 | 2021 |
A Fluorescent Probe for the 70 S‐Ribosomal GTPase‐Associated Center S Schoof, S Baumann, B Ellinger, HD Arndt ChemBioChem 10 (2), 242-245, 2009 | 63 | 2009 |
Generation of Live‐Cell Microarrays by Means of DNA‐Directed Immobilization of Specific Cell‐Surface Ligands H Schroeder, B Ellinger, CFW Becker, H Waldmann, CM Niemeyer Angewandte Chemie International Edition 46 (22), 4180-4183, 2007 | 63 | 2007 |
ATP competitive inhibitors of D-alanine–D-alanine ligase based on protein kinase inhibitor scaffolds G Triola, S Wetzel, B Ellinger, MA Koch, K Hübel, D Rauh, H Waldmann Bioorganic & medicinal chemistry 17 (3), 1079-1087, 2009 | 58 | 2009 |
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs C Borsari, R Luciani, C Pozzi, I Poehner, S Henrich, M Trande, ... Journal of medicinal chemistry 59 (16), 7598-7616, 2016 | 56 | 2016 |
A bioluminogenic HDAC activity assay: validation and screening F Halley, J Reinshagen, B Ellinger, M Wolf, AL Niles, NJ Evans, ... Journal of biomolecular screening 16 (10), 1227-1235, 2011 | 53 | 2011 |
Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a … C Ueck, T Volksdorf, P Houdek, S Vidal-y-Sy, S Sehner, B Ellinger, ... PloS one 12 (1), e0169028, 2017 | 48 | 2017 |
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ... European Journal of Medicinal Chemistry 146, 423-434, 2018 | 42 | 2018 |
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display … E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ... European Journal of Medicinal Chemistry 141, 138-148, 2017 | 37 | 2017 |
Establishing the Secondary Metabolite Profile of the Marine Fungus: Tolypocladium geodes sp. MF458 and Subsequent Optimisation of Bioactive Secondary … B Kebede, SK Wrigley, A Prashar, J Rahlff, M Wolf, J Reinshagen, ... Marine drugs 15 (4), 84, 2017 | 37 | 2017 |
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery P Linciano, A Dawson, I Pöhner, DM Costa, MS Sá, A Cordeiro-da-Silva, ... ACS omega 2 (9), 5666-5683, 2017 | 33 | 2017 |