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Brooke E Harcourt
Brooke E Harcourt
Verified email at mcri.edu.au
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Cited by
Cited by
Year
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
MT Coughlan, DR Thorburn, SA Penfold, A Laskowski, BE Harcourt, ...
Journal of the American Society of Nephrology 20 (4), 742-752, 2009
5102009
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
SZ Hasnain, DJ Borg, BE Harcourt, H Tong, YH Sheng, CP Ng, I Das, ...
Nature medicine 20 (12), 1417-1426, 2014
2612014
Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs
C Tikellis, MC Thomas, BE Harcourt, MT Coughlan, J Pete, K Bialkowski, ...
American Journal of Physiology-Endocrinology and Metabolism 295 (2), E323-E330, 2008
1502008
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy
ALY Tan, KC Sourris, BE Harcourt, V Thallas-Bonke, S Penfold, ...
American Journal of Physiology-Renal Physiology 298 (3), F763-F770, 2010
1462010
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes
KC Sourris, BE Harcourt, PH Tang, AL Morley, K Huynh, SA Penfold, ...
Free Radical Biology and Medicine 52 (3), 716-723, 2012
1452012
Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes
MT Coughlan, TV Nguyen, SA Penfold, GC Higgins, V Thallas-Bonke, ...
Clinical science 130 (9), 711-720, 2016
1442016
Targeted reduction of advanced glycation improves renal function in obesity
BE Harcourt, KC Sourris, MT Coughlan, KZ Walker, SL Dougherty, ...
Kidney international 80 (2), 190-198, 2011
1312011
Coming full circle in diabetes mellitus: from complications to initiation
BE Harcourt, SA Penfold, JM Forbes
Nature Reviews Endocrinology 9 (2), 113-123, 2013
1022013
Processed foods drive intestinal barrier permeability and microvascular diseases
M Snelson, SM Tan, RE Clarke, C De Pasquale, V Thallas-Bonke, ...
Science advances 7 (14), eabe4841, 2021
982021
Deficiency in apoptosis-inducing factor recapitulates chronic kidney disease via aberrant mitochondrial homeostasis
MT Coughlan, GC Higgins, TV Nguyen, SA Penfold, V Thallas-Bonke, ...
Diabetes 65 (4), 1085-1098, 2016
712016
Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy
K Fukami, S Yamagishi, MT Coughlan, BE Harcourt, P Kantharidis, ...
Diabetology & Metabolic Syndrome 6, 1-9, 2014
462014
A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through disparate therapeutic …
KC Sourris, BE Harcourt, JM Forbes
American Journal of Nephrology 30 (4), 323-335, 2009
422009
Targeting the AGE‐RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end‐product content
V Thallas‐Bonke, MT Coughlan, ALY Tan, BE Harcourt, PE Morgan, ...
Nephrology 18 (1), 47-56, 2013
402013
Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy
KC Sourris, BE Harcourt, SA Penfold, FYT Yap, AL Morley, PE Morgan, ...
Journal of Diabetes Research 2010, 2010
342010
Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes
G Tesch, KC Sourris, SA Summers, D McCarthy, MS Ward, DJ Borg, ...
Diabetologia 57, 1977-1985, 2014
322014
Impairment of liver glycogen storage in the db/db animal model of type 2 diabetes: a potential target for future therapeutics?
M A Sullivan, B E Harcourt, P Xu, J M Forbes, R G Gilbert
Current drug targets 16 (10), 1088-1093, 2015
292015
Evidence for protein leverage in children and adolescents with obesity
C Saner, D Tassoni, BE Harcourt, KT Kao, EJ Alexander, Z McCallum, ...
Obesity 28 (4), 822-829, 2020
282020
A rapid extraction method for glycogen from formalin-fixed liver
MA Sullivan, S Li, STN Aroney, B Deng, C Li, E Roura, BL Schulz, ...
Carbohydrate polymers 118, 9-15, 2015
282015
Serum IGFBP‐2 levels are associated with reduced insulin sensitivity in obese children
SW Yau, BE Harcourt, KT Kao, EJ Alexander, VC Russo, GA Werther, ...
Clinical obesity 8 (3), 184-190, 2018
272018
Sex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesity
C Saner, BE Harcourt, A Pandey, S Ellul, Z McCallum, KT Kao, ...
Metabolomics 15, 1-11, 2019
262019
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