| The role of voltage-gated sodium channels in pain signaling DL Bennett, AJ Clark, J Huang, SG Waxman, SD Dib-Hajj Physiological reviews 99 (2), 1079-1151, 2019 | 513 | 2019 |
| Gain-of-function mutations in sodium channel NaV1.9 in painful neuropathy J Huang, C Han, M Estacion, D Vasylyev, JGJ Hoeijmakers, MM Gerrits, ... Brain 137 (6), 1627-1642, 2014 | 291 | 2014 |
| Small-fiber neuropathy Nav1. 8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons J Huang, Y Yang, P Zhao, MM Gerrits, JGJ Hoeijmakers, K Bekelaar, ... Journal of Neuroscience 33 (35), 14087-14097, 2013 | 128 | 2013 |
| Human Nav1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons C Han, M Estacion, J Huang, D Vasylyev, P Zhao, SD Dib-Hajj, ... Journal of neurophysiology 113 (9), 3172-3185, 2015 | 108 | 2015 |
| Sodium channel Nav1.8 Emerging links to human disease C Han, J Huang, SG Waxman Neurology 86 (5), 473-483, 2016 | 105 | 2016 |
| Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain L Chen, J Huang, P Zhao, AK Persson, FB Dib-Hajj, X Cheng, A Tan, ... Scientific reports 8 (1), 3845, 2018 | 90 | 2018 |
| Nav1. 7-A1632G mutation from a family with inherited erythromelalgia: enhanced firing of dorsal root ganglia neurons evoked by thermal stimuli Y Yang, J Huang, MA Mis, M Estacion, L Macala, P Shah, BR Schulman, ... Journal of Neuroscience 36 (28), 7511-7522, 2016 | 83 | 2016 |
| Structural characterization of the fusion core in syncytin, envelope protein of human endogenous retrovirus family W R Gong, X Peng, S Kang, H Feng, J Huang, W Zhang, D Lin, P Tien, ... Biochemical and biophysical research communications 331 (4), 1193-1200, 2005 | 75 | 2005 |
| Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability J Huang, CG Vanoye, A Cutts, YP Goldberg, SD Dib-Hajj, CJ Cohen, ... The Journal of clinical investigation 127 (7), 2805-2814, 2017 | 74 | 2017 |
| Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531 CH Li, Q Zhang, B Teng, SJ Mustafa, JY Huang, HG Yu American Journal of Physiology-Cell Physiology 294 (1), C355-C362, 2008 | 66 | 2008 |
| Defective calcium inactivation causes long QT in obese insulin-resistant rat YC Lin, J Huang, H Kan, V Castranova, JC Frisbee, HG Yu American Journal of Physiology-Heart and Circulatory Physiology 302 (4 …, 2012 | 42 | 2012 |
| Novel mechanism for suppression of hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by receptor-like tyrosine phosphatase-α J Huang, A Huang, Q Zhang, YC Lin, HG Yu Journal of biological chemistry 283 (44), 29912-29919, 2008 | 38 | 2008 |
| Leptin decreases heart rate associated with increased ventricular repolarization via its receptor YC Lin, J Huang, S Hileman, K Martin, R Hull, HG Davis, Mary and Yu Am J Physiol Heart Circ Physiol 309, H1731–H1739, 2015 | 29 | 2015 |
| Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1. 7 in DRG neurons and alters its current properties in an isoform-dependent manner PR Effraim, J Huang, A Lampert, S Stamboulian, P Zhao, JA Black, ... Neurobiology of Pain 6, 100029, 2019 | 27 | 2019 |
| Sodium channel Nav1.6 in sensory neurons contributes to vincristine-induced allodynia L Chen, J Huang, C Benson, KL Lankford, P Zhao, J Carrara, AM Tan, ... Brain 143 (8), 2421-2436, 2020 | 26 | 2020 |
| Depolarized Inactivation Overcomes Impaired Activation to Produce DRG Neuron Hyperexcitability in a Nav1.7 Mutation in a Patient with Distal Limb Pain J Huang, Y Yang, S Dib-Hajj, M van Es, P Zhao, J Salomon, J Drenth, ... The Journal of Neuroscience 34 (37), 12328-12340, 2014 | 26 | 2014 |
| A novel gain-of-function Nav1. 9 mutation in a child with episodic pain J Huang, M Estacion, P Zhao, FB Dib-Hajj, B Schulman, A Abicht, I Kurth, ... Frontiers in Neuroscience 13, 918, 2019 | 25 | 2019 |
| Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation J Huang, MA Mis, B Tanaka, T Adi, M Estacion, S Liu, S Walker, ... Scientific reports 8 (1), 1811, 2018 | 20 | 2018 |
| Rescue of a trafficking defective human pacemaker channel via a novel mechanism: roles of Src, Fyn, and Yes tyrosine kinases YC Lin, J Huang, H Kan, JC Frisbee, HG Yu Journal of biological chemistry 284 (44), 30433-30440, 2009 | 19 | 2009 |
| A 49-residue sequence motif in the C terminus of Nav1. 9 regulates trafficking of the channel to the plasma membrane DV Sizova, J Huang, EJ Akin, M Estacion, C Gomis-Perez, SG Waxman, ... Journal of Biological Chemistry 295 (4), 1077-1090, 2020 | 11 | 2020 |
