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Fred van Leeuwen
Fred van Leeuwen
Netherlands Cancer Institute
Geverifieerd e-mailadres voor nki.nl - Homepage
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Dot1p modulates silencing in yeast by methylation of the nucleosome core
F van Leeuwen, PR Gafken, DE Gottschling
Cell 109 (6), 745-756, 2002
10152002
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, ...
Genes & development 18 (11), 1263, 2004
9942004
β-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei
JH Gommers-Ampt, F Van Leeuwen, ALJ de Beer, JFG Vliegenthart, ...
Cell 75 (6), 1129-1136, 1993
2351993
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states
F Frederiks, M Tzouros, G Oudgenoeg, T van Welsem, M Fornerod, ...
Nature structural & molecular biology 15 (6), 550-557, 2008
1922008
Antigenic variation in malaria
P Borst, W Bitter, R McCulloch, F Van Leeuwen, G Rudenko
Cell 82 (1), 1-4, 1995
1751995
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila
O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, ...
The EMBO journal 26 (24), 4974-4984, 2007
1702007
Patterns and mechanisms of ancestral histone protein inheritance in budding yeast
M Radman-Livaja, KF Verzijlbergen, A Weiner, T van Welsem, ...
PLoS biology 9 (6), e1001075, 2011
1642011
β-D-Glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida
P Borst, F van Leeuwen
Molecular and biochemical parasitology 90 (1), 1-8, 1997
163*1997
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei
F van Leeuwen, ER Wijsman, R Kieft, GA van der Marel, JH van Boom, ...
Genes & development 11 (23), 3232-3241, 1997
1521997
β-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres
F Van Leeuwen, MC Taylor, A Mondragon, H Moreau, W Gibson, R Kieft, ...
Proceedings of the National Academy of Sciences 95 (5), 2366-2371, 1998
1501998
Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro
F Martino, S Kueng, P Robinson, M Tsai-Pflugfelder, F van Leeuwen, ...
Molecular cell 33 (3), 323-334, 2009
1352009
The emerging roles of DOT1L in leukemia and normal development
CM McLean, ID Karemaker, F van Leeuwen
Leukemia 28 (11), 2131-2138, 2014
1232014
Genome-wide histone modifications: gaining specificity by preventing promiscuity
F van Leeuwen, DE Gottschling
Current opinion in cell biology 14 (6), 756-762, 2002
1122002
Control of VSG gene expression sites in Trypanosoma brucei
P Borst, W Bitter, PA Blundell, I Chaves, M Cross, H Gerrits, ...
Molecular and biochemical parasitology 91 (1), 67-76, 1998
1081998
CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities
T Ahrends, J Busselaar, TM Severson, N Bąbała, E de Vries, A Bovens, ...
Nature communications 10 (1), 5531, 2019
1052019
Recombination-induced tag exchange to track old and new proteins
KF Verzijlbergen, V Menendez-Benito, T van Welsem, SJ van Deventer, ...
Proceedings of the National Academy of Sciences 107 (1), 64-68, 2010
1052010
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands
F van Leeuwen, ER Wijsman, E Kuyl-Yeheskiely, GA van der Marel, ...
Nucleic acids research 24 (13), 2476-2482, 1996
1021996
Antigenic variation in trypanosomes.
P Borst, G Rudenko, MC Taylor, PA Blundell, F Van Leeuwen, W Bitter, ...
Archives of medical research 27 (3), 379-388, 1996
941996
The upstreams and downstreams of H3K79 methylation by DOT1L
H Vlaming, F van Leeuwen
Chromosoma 125 (4), 593-605, 2016
912016
An N‐terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks
AM Hegnauer, N Hustedt, K Shimada, BL Pike, M Vogel, P Amsler, ...
The EMBO journal 31 (18), 3768-3783, 2012
912012
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Artikelen 1–20