Fred van Leeuwen
Fred van Leeuwen
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The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, ...
Genes & development 18 (11), 1263-1271, 2004
8582004
Dot1p modulates silencing in yeast by methylation of the nucleosome core
F van Leeuwen, PR Gafken, DE Gottschling
Cell 109 (6), 745-756, 2002
8382002
β-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei
JH Gommers-Ampt, F Van Leeuwen, ALJ de Beer, JFG Vliegenthart, ...
Cell 75 (6), 1129-1136, 1993
1911993
Antigenic variation in malaria
P Borst, W Bitter, R McCulloch, F Van Leeuwen, G Rudenko
Cell 82 (1), 1-4, 1995
1711995
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states
F Frederiks, M Tzouros, G Oudgenoeg, T van Welsem, M Fornerod, ...
Nature structural & molecular biology 15 (6), 550-557, 2008
1462008
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila
O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, ...
The EMBO journal 26 (24), 4974-4984, 2007
1392007
β-D-Glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida
P Borst, F van Leeuwen
Molecular and biochemical parasitology 90 (1), 1-8, 1997
135*1997
Patterns and mechanisms of ancestral histone protein inheritance in budding yeast
M Radman-Livaja, KF Verzijlbergen, A Weiner, T van Welsem, ...
PLoS biology 9 (6), e1001075, 2011
1222011
Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro
F Martino, S Kueng, P Robinson, M Tsai-Pflugfelder, F van Leeuwen, ...
Molecular cell 33 (3), 323-334, 2009
1222009
β-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres
F Van Leeuwen, MC Taylor, A Mondragon, H Moreau, W Gibson, R Kieft, ...
Proceedings of the National Academy of Sciences 95 (5), 2366-2371, 1998
1211998
Localization of the modified base J in telomeric VSG gene expression sites ofTrypanosoma brucei
F van Leeuwen, ER Wijsman, R Kieft, GA van der Marel, JH van Boom, ...
Genes & development 11 (23), 3232-3241, 1997
1211997
Control of VSG gene expression sites in Trypanosoma brucei
P Borst, W Bitter, PA Blundell, I Chaves, M Cross, H Gerrits, ...
Molecular and biochemical parasitology 91 (1), 67-76, 1998
1031998
Genome-wide histone modifications: gaining specificity by preventing promiscuity
F van Leeuwen, DE Gottschling
Current opinion in cell biology 14 (6), 756-762, 2002
982002
Antigenic variation in trypanosomes.
P Borst, G Rudenko, MC Taylor, PA Blundell, F Van Leeuwen, W Bitter, ...
Archives of medical research 27 (3), 379-388, 1996
901996
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands
F van Leeuwen, ER Wijsman, E Kuyl-Yeheskiely, GA van der Marel, ...
Nucleic acids research 24 (13), 2476-2482, 1996
861996
The modified base J is the target for a nove lDNA‐binding protein in kinetoplastid protozoans
M Cross, R Kieft, R Sabatini, M Wilm, M de Kort, GA van der Marel, ...
The EMBO Journal 18 (22), 6573-6581, 1999
821999
Biosynthesis and Function of the Modified DNA Base β-d-Glucosyl-Hydroxymethyluracil inTrypanosoma brucei
F van Leeuwen, R Kieft, M Cross, P Borst
Molecular and cellular biology 18 (10), 5643-5651, 1998
791998
Assays for gene silencing in yeast
F Van Leeuwen, DE Gottschling
Methods in enzymology 350, 165-186, 2002
772002
Recombination-induced tag exchange to track old and new proteins
KF Verzijlbergen, V Menendez-Benito, T van Welsem, SJ van Deventer, ...
Proceedings of the National Academy of Sciences 107 (1), 64-68, 2010
722010
Tandemly repeated DNA is a target for the partial replacement of thymine by β-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei
F van Leeuwen, R Kieft, M Cross, P Borst
Molecular and biochemical parasitology 109 (2), 133-145, 2000
672000
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Artikelen 1–20