| Dot1p modulates silencing in yeast by methylation of the nucleosome core F van Leeuwen, PR Gafken, DE Gottschling Cell 109 (6), 745-756, 2002 | 1033 | 2002 |
| The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, ... Genes & development 18 (11), 1263-1271, 2004 | 1004 | 2004 |
| β-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei JH Gommers-Ampt, F Van Leeuwen, ALJ de Beer, JFG Vliegenthart, ... Cell 75 (6), 1129-1136, 1993 | 241 | 1993 |
| Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states F Frederiks, M Tzouros, G Oudgenoeg, T van Welsem, M Fornerod, ... Nature structural & molecular biology 15 (6), 550-557, 2008 | 203 | 2008 |
| Antigenic variation in malaria P Borst, W Bitter, R McCulloch, F Van Leeuwen, G Rudenko Cell 82 (1), 1-4, 1995 | 178 | 1995 |
| Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, ... The EMBO journal 26 (24), 4974-4984, 2007 | 174 | 2007 |
| Patterns and mechanisms of ancestral histone protein inheritance in budding yeast M Radman-Livaja, KF Verzijlbergen, A Weiner, T van Welsem, ... PLoS biology 9 (6), e1001075, 2011 | 169 | 2011 |
| β-D-Glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida P Borst, F van Leeuwen Molecular and biochemical parasitology 90 (1), 1-8, 1997 | 169* | 1997 |
| Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei F van Leeuwen, ER Wijsman, R Kieft, GA van der Marel, JH van Boom, ... Genes & development 11 (23), 3232-3241, 1997 | 155 | 1997 |
| β-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres F Van Leeuwen, MC Taylor, A Mondragon, H Moreau, W Gibson, R Kieft, ... Proceedings of the National Academy of Sciences 95 (5), 2366-2371, 1998 | 152 | 1998 |
| Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro F Martino, S Kueng, P Robinson, M Tsai-Pflugfelder, F van Leeuwen, ... Molecular cell 33 (3), 323-334, 2009 | 140 | 2009 |
| The emerging roles of DOT1L in leukemia and normal development CM McLean, ID Karemaker, F van Leeuwen Leukemia 28 (11), 2131-2138, 2014 | 131 | 2014 |
| CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities T Ahrends, J Busselaar, TM Severson, N Bąbała, E de Vries, A Bovens, ... Nature communications 10 (1), 5531, 2019 | 115 | 2019 |
| Genome-wide histone modifications: gaining specificity by preventing promiscuity F van Leeuwen, DE Gottschling Current opinion in cell biology 14 (6), 756-762, 2002 | 113 | 2002 |
| Recombination-induced tag exchange to track old and new proteins KF Verzijlbergen, V Menendez-Benito, T van Welsem, SJ van Deventer, ... Proceedings of the National Academy of Sciences 107 (1), 64-68, 2010 | 111 | 2010 |
| Control of VSG gene expression sites in Trypanosoma brucei P Borst, W Bitter, PA Blundell, I Chaves, M Cross, H Gerrits, ... Molecular and biochemical parasitology 91 (1), 67-76, 1998 | 106 | 1998 |
| The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands F van Leeuwen, ER Wijsman, E Kuyl-Yeheskiely, GA van der Marel, ... Nucleic acids research 24 (13), 2476-2482, 1996 | 103 | 1996 |
| The upstreams and downstreams of H3K79 methylation by DOT1L H Vlaming, F van Leeuwen Chromosoma 125 (4), 593-605, 2016 | 100 | 2016 |
| Antigenic variation in trypanosomes. P Borst, G Rudenko, MC Taylor, PA Blundell, F Van Leeuwen, W Bitter, ... Archives of medical research 27 (3), 379-388, 1996 | 94 | 1996 |
| An N‐terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks AM Hegnauer, N Hustedt, K Shimada, BL Pike, M Vogel, P Amsler, ... The EMBO journal 31 (18), 3768-3783, 2012 | 93 | 2012 |
Daniel GottschlingPrincipal Investigator, CalicoVerified email at calicolabs.com
