Design, synthesis and evaluation of genistein-O-alkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease X Qiang, Z Sang, W Yuan, Y Li, Q Liu, P Bai, Y Shi, W Ang, Z Tan, Y Deng European Journal of Medicinal Chemistry 76, 314-331, 2014 | 96 | 2014 |
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease Z Sang, W Pan, K Wang, Q Ma, L Yu, Y Yang, P Bai, C Leng, Q Xu, X Li, ... European journal of medicinal chemistry 130, 379-392, 2017 | 84 | 2017 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease P Bai, K Wang, P Zhang, J Shi, X Cheng, Q Zhang, C Zheng, Y Cheng, ... European journal of medicinal chemistry 183, 111737, 2019 | 53 | 2019 |
Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer’s disease W Pan, K Hu, P Bai, L Yu, Q Ma, T Li, X Zhang, C Chen, K Peng, W Liu, ... Bioorganic & medicinal chemistry letters 26 (10), 2539-2543, 2016 | 44 | 2016 |
Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease Z Sang, K Wang, P Bai, A Wu, J Shi, W Liu, G Zhu, Y Wang, Y Lan, Z Chen, ... European Journal of Medicinal Chemistry 194, 112265, 2020 | 32 | 2020 |
Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET) Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, ... Acta Pharmaceutica Sinica B 9 (6), 1204-1215, 2019 | 20 | 2019 |
Positron emission tomography probes targeting bromodomain and extra-terminal (BET) domains to enable in vivo neuroepigenetic imaging P Bai, HY Wey, D Patnaik, X Lu, Y Lan, J Rokka, F Stephanie, ... Chemical communications 55 (86), 12932-12935, 2019 | 15 | 2019 |
Design, synthesis, and insecticidal activity of novel doramectin derivatives containing acylurea and acylthiourea based on hydrogen bonding Q Zhang, Y Cheng, C Zheng, P Bai, J Yang, X Lu Journal of agricultural and food chemistry 68 (21), 5806-5815, 2020 | 14 | 2020 |
Development of a potential PET probe for HDAC6 imaging in Alzheimer's disease P Bai, P Mondal, FA Bagdasarian, N Rani, Y Liu, A Gomm, DR Tocci, ... Acta Pharmaceutica Sinica B 12 (10), 3891-3904, 2022 | 13 | 2022 |
Design, synthesis, insecticidal activity and molecular docking of doramectin derivatives Q Zhang, P Bai, C Zheng, Y Cheng, T Wang, X Lu Bioorganic & Medicinal Chemistry 27 (12), 2387-2396, 2019 | 13 | 2019 |
Design, synthesis, and evaluation of thienodiazepine derivatives as positron emission tomography imaging probes for bromodomain and extra-terminal domain family proteins P Bai, Y Lan, D Patnaik, H Wang, Y Liu, Z Chen, G Yuan, S Afshar, ... Journal of Medicinal Chemistry 64 (19), 14745-14756, 2021 | 12 | 2021 |
Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer Z Chen, X Wang, X Yang, Y Xu, Y Yang, H Wang, T Li, P Bai, G Yuan, ... European Journal of Nuclear Medicine and Molecular Imaging 48, 53-66, 2021 | 12 | 2021 |
A new positron emission tomography probe for orexin receptors neuroimaging P Bai, S Bai, MS Placzek, X Lu, SA Fiedler, B Ntaganda, HY Wey, C Wang Molecules 25 (5), 1018, 2020 | 12 | 2020 |
Degradation and inhibition of epigenetic regulatory protein BRD4 exacerbate Alzheimer’s disease-related neuropathology in cell models S Zhang, P Bai, D Lei, Y Liang, S Zhen, G Bakiasi, H Pang, SH Choi, ... Journal of Biological Chemistry 298 (4), 2022 | 11 | 2022 |
Visualization of receptor-interacting protein kinase 1 (RIPK1) by brain imaging with positron emission tomography Y Lan, P Bai, Y Liu, S Afshar, R Striar, AK Rattray, TN Meyer, AG Langan, ... Journal of medicinal chemistry 64 (20), 15420-15428, 2021 | 11 | 2021 |
Novel donepezil-chalcone-rivastigmine hybrids as potential multifunctional anti-Alzheimer's agents: Design, synthesis, in vitro biological evaluation, in vivo and in silico studies Z Sang, P Bai, Y Ban, K Wang, A Wu, J Mi, J Hu, R Xu, G Zhu, J Wang, ... Bioorganic Chemistry 127, 106007, 2022 | 10 | 2022 |
Radiosynthesis and in vivo evaluation of a new positron emission tomography radiotracer targeting bromodomain and extra-terminal domain (BET) family proteins P Bai, X Lu, Y Lan, Z Chen, D Patnaik, S Fiedler, R Striar, SJ Haggarty, ... Nuclear Medicine and Biology 84, 96-101, 2020 | 8 | 2020 |
Synthesis and characterization of a positron emission tomography imaging probe selectively targeting the second bromodomain of bromodomain protein BRD4 P Bai, Y Lan, H Wang, Y Liu, R Striar, G Yuan, S Afshar, JS Zagaroli, ... Bioconjugate Chemistry 32 (8), 1711-1718, 2021 | 7 | 2021 |
Discovery of a positron emission tomography radiotracer selectively targeting the BD1 bromodomains of BET proteins P Bai, X Lu, Y Liu, Y Lan, H Wang, S Fiedler, R Striar, C Wang ACS Medicinal Chemistry Letters 12 (2), 282-287, 2021 | 7 | 2021 |
Blood tau‐PT217 contributes to the anesthesia/surgery‐induced delirium‐like behavior in aged mice J Lu, F Liang, P Bai, C Liu, M Xu, Z Sun, W Tian, Y Dong, Y Zhang, ... Alzheimer's & Dementia 19 (9), 4110-4126, 2023 | 6 | 2023 |