| Colonic epithelial cell diversity in health and inflammatory bowel disease K Parikh, A Antanaviciute, D Fawkner-Corbett, M Jagielowicz, A Aulicino, ... Nature 567 (7746), 49-55, 2019 | 550 | 2019 |
| Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease J Kinchen, HH Chen, K Parikh, A Antanaviciute, M Jagielowicz, ... Cell 175 (2), 372-386. e17, 2018 | 510 | 2018 |
| Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ... Nature medicine 23 (6), 692-702, 2017 | 397 | 2017 |
| Spatiotemporal analysis of human intestinal development at single-cell resolution D Fawkner-Corbett, A Antanaviciute, K Parikh, M Jagielowicz, AS Gerós, ... Cell 184 (3), 810-826. e23, 2021 | 293 | 2021 |
| Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number H Tyynismaa, H Sembongi, M Bokori-Brown, C Granycome, N Ashley, ... Human molecular genetics 13 (24), 3219-3227, 2004 | 290 | 2004 |
| Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining N Ashley, D Harris, J Poulton Experimental cell research 303 (2), 432-446, 2005 | 185 | 2005 |
| Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs N Ashley, J Poulton Biochemical and biophysical research communications 378 (3), 450-455, 2009 | 181 | 2009 |
| Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways B Psaila, N Barkas, D Iskander, A Roy, S Anderson, N Ashley, VS Caputo, ... Genome biology 17, 1-19, 2016 | 162 | 2016 |
| An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ... Nature immunology 23 (1), 50-61, 2022 | 138 | 2022 |
| Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers L Hsia, N Ashley, D Ouaret, LM Wang, J Wilding, WF Bodmer Proceedings of the National Academy of Sciences 113 (15), E2162-E2171, 2016 | 103 | 2016 |
| Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations C Liao, N Ashley, A Diot, K Morten, K Phadwal, A Williams, I Fearnley, ... Neurology 88 (2), 131-142, 2017 | 95 | 2017 |
| Separation of cancer cells from white blood cells by pinched flow fractionation M Pødenphant, N Ashley, K Koprowska, KU Mir, M Zalkovskij, B Bilenberg, ... Lab on a Chip 15 (24), 4598-4606, 2015 | 87 | 2015 |
| Liver mtDNA content increases during development: a comparison of methods and the importance of age-and tissue-specific controls for the diagnosis of mtDNA depletion KJ Morten, N Ashley, F Wijburg, N Hadzic, J Parr, S Jayawant, S Adams, ... Mitochondrion 7 (6), 386-395, 2007 | 83 | 2007 |
| Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene J Uusimaa, J Evans, C Smith, A Butterworth, K Craig, N Ashley, C Liao, ... European Journal of Human Genetics 22 (2), 184-191, 2014 | 82 | 2014 |
| Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations N Ashley, A O'Rourke, C Smith, S Adams, V Gowda, M Zeviani, GK Brown, ... Human molecular genetics 17 (16), 2496-2506, 2008 | 72 | 2008 |
| Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia LM Moreira, A Takawale, M Hulsurkar, DA Menassa, A Antanaviciute, ... Nature 587 (7834), 460-465, 2020 | 62 | 2020 |
| Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling N Ashley, J Poulton Oncogene 28 (44), 3880-3891, 2009 | 61 | 2009 |
| Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances N Ashley, S Adams, A Slama, M Zeviani, A Suomalainen, AL Andreu, ... Human molecular genetics 16 (12), 1400-1411, 2007 | 60 | 2007 |
| Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ... Nature communications 8 (1), 403, 2017 | 59 | 2017 |
| Ezh2 and Runx1 mutations collaborate to initiate lympho-myeloid leukemia in early thymic progenitors CAG Booth, N Barkas, WH Neo, H Boukarabila, EJ Soilleux, ... Cancer Cell 33 (2), 274-291. e8, 2018 | 58 | 2018 |
