| The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis G Siegfried, A Basak, JA Cromlish, S Benjannet, J Marcinkiewicz, ... The Journal of clinical investigation 111 (11), 1723-1732, 2003 | 319 | 2003 |
| Proprotein convertases: lessons from knockouts N Scamuffa, F Calvo, M Chrétien, NG Seidah, AM Khatib The FASEB Journal 20 (12), 1954-1963, 2006 | 281 | 2006 |
| Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy AM Khatib, G Siegfried, M Chrétien, P Metrakos, NG Seidah The American journal of pathology 160 (6), 1921-1935, 2002 | 259 | 2002 |
| Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells AM Khatib, M Kontogiannea, L Fallavollita, B Jamison, S Meterissian, ... Cancer research 59 (6), 1356-1361, 1999 | 224 | 1999 |
| Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF … AM Khatib, G Siegfried, A Prat, J Luis, M Chrétien, P Metrakos, NG Seidah Journal of Biological Chemistry 276 (33), 30686-30693, 2001 | 207 | 2001 |
| Characterization of the host proinflammatory response to tumor cells during the initial stages of liver metastasis AM Khatib, P Auguste, L Fallavollita, N Wang, A Samani, M Kontogiannea, ... The American journal of pathology 167 (3), 749-759, 2005 | 173 | 2005 |
| Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis AM Khatib, L Fallavollita, EV Wancewicz, BP Monia, P Brodt Cancer Research 62 (19), 5393-5398, 2002 | 150 | 2002 |
| Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells N Scamuffa, G Siegfried, Y Bontemps, L Ma, A Basak, G Cherel, F Calvo, ... The Journal of clinical investigation 118 (1), 352-363, 2008 | 149 | 2008 |
| The proprotein convertases and their implication in sterol and/or lipid metabolism NG Seidah, AM Khatib, A Prat Walter de Gruyter 387 (7), 871-877, 2006 | 143 | 2006 |
| Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver X Sun, R Essalmani, R Day, AM Khatib, NG Seidah, A Prat Neoplasia 14 (12), 1122-IN5, 2012 | 135 | 2012 |
| Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor β subunit P Brodt, L Fallavollita, AM Khatib, AA Samani, D Zhang Journal of Biological Chemistry 276 (36), 33608-33615, 2001 | 127 | 2001 |
| Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving the transcription factor NF-κB in human osteosarcoma M Felx, MC Guyot, M Isler, RE Turcotte, J Doyon, AM Khatib, S Leclerc, ... Clinical science 110 (6), 645-654, 2006 | 126 | 2006 |
| The Proteolytic Processing of Pro-Platelet-derived Growth Factor-A at RRKR86 by Members of the Proprotein Convertase Family Is Functionally Correlated to … G Siegfried, AM Khatib, S Benjannet, M Chrétien, NG Seidah Cancer research 63 (7), 1458-1463, 2003 | 115 | 2003 |
| Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function K Ramgolam, J Lauriol, C Lalou, L Lauden, L Michel, P de La Grange, ... PloS one 6 (4), e18784, 2011 | 109 | 2011 |
| Knock-out mouse models of proprotein convertases: unique functions or redundancy JW Creemers, AM Khatib Front Biosci 13 (5), 4960-4971, 2008 | 107 | 2008 |
| Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases G Siegfried, A Basak, W Prichett-Pejic, N Scamuffa, L Ma, S Benjannet, ... Oncogene 24 (46), 6925-6935, 2005 | 99 | 2005 |
| In silico investigation of the new UK (B. 1.1. 7) and South African (501y. v2) SARS-CoV-2 variants with a focus at the ace2–spike rbd interface BO Villoutreix, V Calvez, AG Marcelin, AM Khatib International journal of molecular sciences 22 (4), 1695, 2021 | 91 | 2021 |
| Articular chondrocytes from aging rats respond poorly to insulin-like growth factor-1: an altered signaling pathway H Messai, Y Duchossoy, AM Khatib, A Panasyuk, DR Mitrovic Mechanisms of ageing and development 115 (1-2), 21-37, 2000 | 83 | 2000 |
| Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells' malignant phenotypes: role of tissue inhibitors of metalloproteinase-1 M Lapierre, G Siegfried, N Scamuffa, Y Bontemps, F Calvo, NG Seidah, ... Cancer Research 67 (19), 9030-9034, 2007 | 80 | 2007 |
| Tumor necrosis factor-α down-regulates human Cu/Zn superoxide dismutase 1 promoter via JNK/AP-1 signaling pathway V Afonso, G Santos, P Collin, AM Khatib, DR Mitrovic, N Lomri, ... Free Radical Biology and Medicine 41 (5), 709-721, 2006 | 80 | 2006 |
Nabil SeidahIRCMVerified email at ircm.qc.ca
