Heinz Jacobs
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Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert
S Ariotti, MA Hogenbirk, FE Dijkgraaf, LL Visser, ME Hoekstra, JY Song, ...
Science 346 (6205), 101-105, 2014
Heterogeneous differentiation patterns of individual CD8+ T cells
C Gerlach, JC Rohr, L Perié, N van Rooij, JWJ Van Heijst, A Velds, ...
Science 340 (6132), 635-639, 2013
Somatic hypermutation in the heavy chain locus correlates with transcription
Y Fukita, H Jacobs, K Rajewsky
Immunity 9 (1), 105-114, 1998
DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation
L Bross, Y Fukita, F McBlane, C Démollière, K Rajewsky, H Jacobs
Immunity 13 (5), 589-597, 2000
Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis
RH Wilting, E Yanover, MR Heideman, H Jacobs, J Horner, ...
The EMBO journal 29 (15), 2586-2597, 2010
Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice
JG Jansen, P Langerak, A Tsaalbi-Shtylik, P van den Berk, H Jacobs, ...
The Journal of experimental medicine 203 (2), 319-323, 2006
CD3 components at the surface of pro‐T cells can mediate pre‐T cell development in vivo
H Jacobs, D Vandeputte, L Tolkamp, E De Vries, J Borst, A Berns
European journal of immunology 24 (4), 934-939, 1994
CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness
T Ahrends, A Spanjaard, B Pilzecker, N Bąbała, A Bovens, Y Xiao, ...
Immunity 47 (5), 848-861. e5, 2017
Perturbation of B and T cell development and predisposition to lymphomagenesis in Eμ Bmi 1 transgenic mice require the Bmi1 RING finger
MJ Alkema, H Jacobs, M van Lohuizen, A Berns
Oncogene 15 (8), 899-910, 1997
CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation
Y Xiao, J Hendriks, P Langerak, H Jacobs, J Borst
The Journal of Immunology 172 (12), 7432-7441, 2004
A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification
P Langerak, AOH Nygren, PHL Krijger, PCM van den Berk, H Jacobs
The Journal of experimental medicine 204 (8), 1989-1998, 2007
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27–CD70 pathway
JM Coquet, JC Ribot, N Bąbała, S Middendorp, G van der Horst, Y Xiao, ...
Journal of Experimental Medicine 210 (4), 715-728, 2013
PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells
A Hendel, PHL Krijger, N Diamant, Z Goren, P Langerak, J Kim, T Reißner, ...
PLoS genetics 7 (9), e1002262, 2011
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity
M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ...
Molecular cell 67 (5), 882-890. e5, 2017
Hypermutation of immunoglobulin genes in memory B cells of DNA repair–deficient mice
H Jacobs, Y Fukita, GTJ Van Der Horst, J De Boer, G Weeda, J Essers, ...
The Journal of experimental medicine 187 (11), 1735-1743, 1998
Towards an understanding of somatic hypermutation
H Jacobs, L Bross
Current opinion in immunology 13 (2), 208-218, 2001
Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers
AM Sieuwerts, S Willis, MB Burns, MP Look, ME Meijer-Van Gelder, ...
Hormones and Cancer 5 (6), 405-413, 2014
The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity
JM Coquet, S Middendorp, G van der Horst, J Kind, EAM Veraar, Y Xiao, ...
Immunity 38 (1), 53-65, 2013
The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis
JG Jansen, A Tsaalbi-Shtylik, P Langerak, F Calleja, CM Meijers, ...
Nucleic acids research 33 (1), 356-365, 2005
Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes
J Borst, H Jacobs, G Brouns
Current opinion in immunology 8 (2), 181-190, 1996
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