| Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert S Ariotti, MA Hogenbirk, FE Dijkgraaf, LL Visser, ME Hoekstra, JY Song, ... Science 346 (6205), 101-105, 2014 | 564 | 2014 |
| Heterogeneous Differentiation Patterns of Individual CD8+ T Cells C Gerlach, JC Rohr, L Perié, N Van Rooij, JWJ Van Heijst, A Velds, ... Science 340 (6132), 635-639, 2013 | 423 | 2013 |
| CD4+ T cell help confers a cytotoxic T cell effector program including coinhibitory receptor downregulation and increased tissue invasiveness T Ahrends, A Spanjaard, B Pilzecker, N Bąbała, A Bovens, Y Xiao, ... Immunity 47 (5), 848-861. e5, 2017 | 346 | 2017 |
| Somatic hypermutation in the heavy chain locus correlates with transcription Y Fukita, H Jacobs, K Rajewsky Immunity 9 (1), 105-114, 1998 | 335 | 1998 |
| Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis RH Wilting, E Yanover, MR Heideman, H Jacobs, J Horner, ... The EMBO journal 29 (15), 2586-2597, 2010 | 277 | 2010 |
| Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice JG Jansen, P Langerak, A Tsaalbi-Shtylik, P van den Berk, H Jacobs, ... The Journal of experimental medicine 203 (2), 319-323, 2006 | 258 | 2006 |
| DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation L Bross, Y Fukita, F McBlane, C Démollière, K Rajewsky, H Jacobs Immunity 13 (5), 589-597, 2000 | 239 | 2000 |
| Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ... Molecular cell 67 (5), 882-890. e5, 2017 | 233 | 2017 |
| A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification P Langerak, AOH Nygren, PHL Krijger, PCM van den Berk, H Jacobs The Journal of experimental medicine 204 (8), 1989-1998, 2007 | 182 | 2007 |
| Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27–CD70 pathway JM Coquet, JC Ribot, N Bąbała, S Middendorp, G van der Horst, Y Xiao, ... Journal of Experimental Medicine 210 (4), 715-728, 2013 | 181 | 2013 |
| CD3 components at the surface of pro‐T cells can mediate pre‐T cell development in vivo H Jacobs, D Vandeputte, L Tolkamp, E De Vries, J Borst, A Berns European journal of immunology 24 (4), 934-939, 1994 | 176 | 1994 |
| Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers AM Sieuwerts, S Willis, MB Burns, MP Look, MEMV Gelder, A Schlicker, ... Hormones and Cancer 5, 405-413, 2014 | 174 | 2014 |
| CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation Y Xiao, J Hendriks, P Langerak, H Jacobs, J Borst The Journal of Immunology 172 (12), 7432-7441, 2004 | 173 | 2004 |
| PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells A Hendel, PHL Krijger, N Diamant, Z Goren, P Langerak, J Kim, ... PLoS genetics 7 (9), e1002262, 2011 | 167 | 2011 |
| Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger MJ Alkema, H Jacobs, M van Lohuizen, A Berns Oncogene 15 (8), 899-910, 1997 | 163 | 1997 |
| Towards an understanding of somatic hypermutation H Jacobs, L Bross Current Opinion in Immunology 13 (2), 208-218, 2001 | 146 | 2001 |
| Hypermutation of immunoglobulin genes in memory B cells of DNA repair–deficient mice H Jacobs, Y Fukita, GTJ Van Der Horst, J De Boer, G Weeda, J Essers, ... The Journal of experimental medicine 187 (11), 1735-1743, 1998 | 134 | 1998 |
| The CD27 and CD70 costimulatory pathway inhibits effector function of T helper 17 cells and attenuates associated autoimmunity JM Coquet, S Middendorp, G van der Horst, J Kind, EAM Veraar, Y Xiao, ... Immunity 38 (1), 53-65, 2013 | 122 | 2013 |
| The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis JG Jansen, A Tsaalbi-Shtylik, P Langerak, F Calleja, CM Meijers, ... Nucleic acids research 33 (1), 356-365, 2005 | 114 | 2005 |
| Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes J Borst, H Jacobs, G Brouns Current opinion in immunology 8 (2), 181-190, 1996 | 114 | 1996 |
