Hepatitis C virus NS5A: tales of a promiscuous protein A Macdonald, M Harris Journal of General Virology 85 (9), 2485-2502, 2004 | 523 | 2004 |
The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade A Street, A Macdonald, K Crowder, M Harris Journal of Biological Chemistry 279 (13), 12232-12241, 2004 | 284 | 2004 |
Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4 N McFadden, D Bailey, G Carrara, A Benson, Y Chaudhry, A Shortland, ... PLoS pathogens 7 (12), e1002413, 2011 | 279 | 2011 |
Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL A Macdonald, DG Campbell, R Toth, H McLauchlan, CJ Hastie, ... BMC cell biology 7, 1-14, 2006 | 219 | 2006 |
The Hepatitis C Virus Non-structural NS5A Protein Inhibits Activating Protein–1 Function by Perturbing Ras-ERK Pathway Signaling A Macdonald, K Crowder, A Street, C McCormick, K Saksela, M Harris Journal of Biological Chemistry 278 (20), 17775-17784, 2003 | 197 | 2003 |
Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular β-catenin and stimulation of β-catenin-responsive transcription A Street, A Macdonald, C McCormick, M Harris Journal of virology 79 (8), 5006-5016, 2005 | 170 | 2005 |
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity A Macdonald, K Crowder, A Street, C McCormick, M Harris Journal of General Virology 85 (3), 721-729, 2004 | 165 | 2004 |
The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation JA Scarth, MR Patterson, EL Morgan, A Macdonald Journal of General Virology 102 (3), 001540, 2021 | 162 | 2021 |
miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity J Remenyi, MWM van den Bosch, O Palygin, RB Mistry, C McKenzie, ... PloS one 8 (4), e62509, 2013 | 160 | 2013 |
Optineurin negatively regulates the induction of IFNβ in response to RNA virus infection J Mankouri, R Fragkoudis, KH Richards, LF Wetherill, M Harris, A Kohl, ... PLoS pathogens 6 (2), e1000778, 2010 | 145 | 2010 |
High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors LF Wetherill, KK Holmes, M Verow, M Müller, G Howell, M Harris, ... Journal of virology 86 (9), 5341-5351, 2012 | 134 | 2012 |
Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis EL Morgan, A Macdonald PLoS pathogens 15 (6), e1007835, 2019 | 123 | 2019 |
Merkel cell polyomavirus small T antigen targets the NEMO adaptor protein to disrupt inflammatory signaling DA Griffiths, H Abdul-Sada, LM Knight, BR Jackson, K Richards, ... Journal of virology 87 (24), 13853-13867, 2013 | 119 | 2013 |
Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ... Angewandte Chemie 127 (10), 3003-3008, 2015 | 111 | 2015 |
Quantitative proteomics using stable isotope labeling with amino acids in cell culture reveals changes in the cytoplasmic, nuclear, and nucleolar proteomes in Vero cells … E Emmott, MA Rodgers, A Macdonald, S McCrory, P Ajuh, JA Hiscox Molecular & Cellular Proteomics 9 (9), 1920-1936, 2010 | 92 | 2010 |
New structural insights into the genome and minor capsid proteins of BK polyomavirus using cryo-electron microscopy DL Hurdiss, EL Morgan, RF Thompson, EL Prescott, MM Panou, ... Structure 24 (4), 528-536, 2016 | 88 | 2016 |
Merkel cell polyomavirus small T antigen mediates microtubule destabilization to promote cell motility and migration LM Knight, G Stakaityte, JJ Wood, H Abdul-Sada, DA Griffiths, GJ Howell, ... Journal of virology 89 (1), 35-47, 2015 | 88 | 2015 |
Identification of TRIM23 as a cofactor involved in the regulation of NF-κB by human cytomegalovirus E Poole, I Groves, A Macdonald, Y Pang, A Alcami, J Sinclair Journal of virology 83 (8), 3581-3590, 2009 | 85 | 2009 |
Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence J Mankouri, ML Dallas, ME Hughes, SDC Griffin, A Macdonald, C Peers, ... Proceedings of the National Academy of Sciences 106 (37), 15903-15908, 2009 | 79 | 2009 |
STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle EL Morgan, CW Wasson, L Hanson, D Kealy, I Pentland, V McGuire, ... PLoS pathogens 14 (4), e1006975, 2018 | 77 | 2018 |