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Jürgen Harder
Jürgen Harder
Professor of Epithelial Infection Biology, University of Kiel
Geverifieerd e-mailadres voor dermatology.uni-kiel.de
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Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic
J Harder, J Bartels, E Christophers, JM Schröder
Journal of Biological Chemistry 276 (8), 5707-5713, 2001
19342001
A peptide antibiotic from human skin
J Harder, J Bartels, E Christophers, JM Schröder
Nature 387 (6636), 861-861, 1997
19281997
NOD2 (CARD15) mutations in Crohn’s disease are associated with diminished mucosal α-defensin expression
J Wehkamp, J Harder, M Weichenthal, M Schwab, E Schäffeler, M Schlee, ...
Gut 53 (11), 1658-1664, 2004
11232004
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection
R Gläser, J Harder, H Lange, J Bartels, E Christophers, JM Schröder
Nature immunology 6 (1), 57-64, 2005
7912005
NF-κB-and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium
J Wehkamp, J Harder, K Wehkamp, B Wehkamp-von Meissner, M Schlee, ...
Infection and immunity 72 (10), 5750-5758, 2004
6712004
Human beta-defensin-2
JM Schröder, J Harder
The international journal of biochemistry & cell biology 31 (6), 645-651, 1999
6661999
Mucoid Pseudomonas aeruginosa, TNF-α, and IL-1 β, but Not IL-6, Induce Human β-Defensin-2 in Respiratory Epithelia
J Harder, U Meyer-Hoffert, LM Teran, L Schwichtenberg, J Bartels, ...
American Journal of Respiratory Cell and Molecular Biology 22 (6), 714-721, 2000
6362000
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
J Harder, JM Schröder
Journal of Biological Chemistry 277 (48), 46779-46784, 2002
5472002
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions
Y Dombrowski, M Peric, S Koglin, C Kammerbauer, C Göß, D Anz, ...
Science translational medicine 3 (82), 82ra38-82ra38, 2011
4702011
Probiotic lactobacilli and VSL# 3 induce enterocyte β‐defensin 2
M Schlee, J Harder, B Köten, EF Stange, J Wehkamp, K Fellermann
Clinical & Experimental Immunology 151 (3), 528-535, 2008
4662008
Inducible and constitutive β‐defensins are differentially expressed in Crohn's disease and ulcerative colitis
J Wehkamp, J Harder, M Weichenthal, O Mueller, KR Herrlinger, ...
Inflammatory bowel diseases 9 (4), 215-223, 2003
4612003
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2
E Voss, J Wehkamp, K Wehkamp, EF Stange, JM Schröder, J Harder
Journal of Biological Chemistry 281 (4), 2005-2011, 2006
4242006
Antimicrobial skin peptides and proteins
JM Schröder, J Harder
Cellular and Molecular Life Sciences CMLS 63 (4), 469-486, 2006
3582006
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins
J Harder, JM Schröder
Journal of leukocyte biology 77 (4), 476-486, 2005
3112005
Differential gene induction of human β-defensins (hBD-1,-2,-3, and-4) in keratinocytes is inhibited by retinoic acid
J Harder, U Meyer-Hoffert, K Wehkamp, L Schwichtenberg, JM Schröder
Journal of Investigative Dermatology 123 (3), 522-529, 2004
3002004
Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury
J Harder, S Dressel, M Wittersheim, J Cordes, U Meyer-Hoffert, ...
Journal of Investigative Dermatology 130 (5), 1355-1364, 2010
2992010
Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1α released from dying cells
T Eigenbrod, JH Park, J Harder, Y Iwakura, G Núñez
The Journal of Immunology 181 (12), 8194-8198, 2008
2992008
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-κB activation but proceeds independently of TLR signaling and P2X7 receptor
J Harder, L Franchi, R Muñoz-Planillo, JH Park, T Reimer, G Núñez
The Journal of Immunology 183 (9), 5823-5829, 2009
2912009
Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines
J Lehmann, M Retz, SS Sidhu, H Suttmann, M Sell, F Paulsen, J Harder, ...
European urology 50 (1), 141-147, 2006
2712006
Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence
TCG Bosch, R Augustin, F Anton-Erxleben, S Fraune, G Hemmrich, H Zill, ...
Developmental & Comparative Immunology 33 (4), 559-569, 2009
2642009
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Artikelen 1–20