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Eva Czirr
Eva Czirr
Sr. Scientist
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Year
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
SA Villeda, J Luo, KI Mosher, B Zou, M Britschgi, G Bieri, TM Stan, ...
Nature 477 (7362), 90-94, 2011
18342011
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ...
Science translational medicine 6 (243), 243ra86-243ra86, 2014
7332014
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer’s disease
KM Lucin, CE O’Brien, G Bieri, E Czirr, KI Mosher, RJ Abbey, ...
Neuron 79 (5), 873-886, 2013
4042013
The immunology of neurodegeneration
E Czirr, T Wyss-Coray
The Journal of clinical investigation 122 (4), 1156-1163, 2012
2402012
Preclinical assessment of young blood plasma for Alzheimer disease
J Middeldorp, B Lehallier, SA Villeda, SSM Miedema, E Evans, E Czirr, ...
JAMA neurology 73 (11), 1325-1333, 2016
1522016
Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity
E Czirr, NA Castello, KI Mosher, JM Castellano, IV Hinkson, KM Lucin, ...
Journal of Experimental Medicine 214 (4), 1081-1092, 2017
1012017
Independent generation of Aβ42 and Aβ38 peptide species by γ-secretase
E Czirr, BA Cottrell, S Leuchtenberger, T Kukar, TB Ladd, H Esselmann, ...
Journal of biological chemistry 283 (25), 17049-17054, 2008
902008
Outer dense fibre protein 2 (ODF2) is a self-interacting centrosomal protein with affinity for microtubules
FF Donkor, M Mönnich, E Czirr, T Hollemann, S Hoyer-Fender
Journal of Cell Science 117 (20), 4643-4651, 2004
902004
Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome
WW Li, TZ Guo, X Shi, E Czirr, T Stan, P Sahbaie, T Wyss-Coray, ...
PAIN® 155 (11), 2377-2389, 2014
872014
α‐secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation
S Jäger, S Leuchtenberger, A Martin, E Czirr, J Wesselowski, ...
Journal of neurochemistry 111 (6), 1369-1382, 2009
782009
Insensitivity to Aβ42-lowering Nonsteroidal Anti-inflammatory Drugs and γ-Secretase Inhibitors Is Common among Aggressive Presenilin-1 Mutations*♦
E Czirr, S Leuchtenberger, C Dorner-Ciossek, A Schneider, M Jucker, ...
Journal of Biological Chemistry 282 (34), 24504-24513, 2007
752007
Genetic variation in oocyte phenotype revealed through parthenogenesis and cloning: correlation with differences in pronuclear epigenetic modification
S Gao, E Czirr, YG Chung, Z Han, KE Latham
Biology of Reproduction 70 (4), 1162-1170, 2004
722004
Presenilin‐1 but not amyloid precursor protein mutations present in mouse models of Alzheimer’s disease attenuate the response of cultured cells to γ‐secretase modulators …
S Hahn, T Brüning, J Ness, E Czirr, S Baches, H Gijsen, C Korth, ...
Journal of neurochemistry 116 (3), 385-395, 2011
552011
Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42
S Leuchtenberger, MP Kummer, T Kukar, E Czirr, N Teusch, SA Sagi, ...
Journal of neurochemistry 96 (2), 355-365, 2006
482006
γ-Secretase modulation with Aβ42-lowering nonsteroidal anti-inflammatory drugs and derived compounds
E Czirr, S Weggen
Neurodegenerative diseases 3 (4-5), 298-304, 2006
462006
Localisation of histone macroH2A1. 2 to the XY-body is not a response to the presence of asynapsed chromosome axes
S Hoyer-Fender, E Czirr, R Radde, JMA Turner, SK Mahadevaiah, ...
Journal of cell science 117 (2), 189-198, 2004
212004
Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein
S Leuchtenberger, J Maler, E Czirr, J Ness, SF Lichtenthaler, ...
Neurodegenerative diseases 6 (1-2), 1-8, 2008
132008
Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
SP Braithwaite, E Czirr, I Gallager, N Huber, SS Minami
US Patent 10,357,513, 2019
122019
Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
R Britton, AT Liu, SV Rege, JM Adams, L Akrapongpisak, D Le, ...
Brain and Behavior 12 (9), e2736, 2022
62022
Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
SP Braithwaite, MK Campbell, E Czirr, I Gallager, N Huber, S Jackson, ...
US Patent 11,040,068, 2021
42021
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