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Darrell Sleep
Darrell Sleep
Cobra Biologics Ltd
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Albumin as a versatile platform for drug half-life extension
D Sleep, J Cameron, LR Evans
Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (12), 5526-5534, 2013
5502013
Albumin and its application in drug delivery
D Sleep
Expert opinion on drug delivery 12 (5), 793-812, 2015
4102015
Interdomain zinc site on human albumin
AJ Stewart, CA Blindauer, S Berezenko, D Sleep, PJ Sadler
Proceedings of the National Academy of Sciences 100 (7), 3701-3706, 2003
2412003
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
JT Andersen, B Dalhus, J Cameron, MB Daba, A Plumridge, L Evans, ...
Nature communications 3 (1), 610, 2012
2082012
The Secretion of Human Serum Albumin from the Yeast Saccharomyces cerevisiae Using Five Different Leader Sequences
D Sleep, GP Belfield, AR Goodey
Bio/technology 8 (1), 42-46, 1990
2031990
Structure, properties, and engineering of the major zinc binding site on human albumin
CA Blindauer, I Harvey, KE Bunyan, AJ Stewart, D Sleep, DJ Harrison, ...
Journal of Biological Chemistry 284 (34), 23116-23124, 2009
1882009
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding
JT Andersen, B Dalhus, D Viuff, BT Ravn, KS Gunnarsen, A Plumridge, ...
Journal of Biological Chemistry 289 (19), 13492-13502, 2014
1852014
Role of Tyr84 in controlling the reactivity of Cys34 of human albumin
AJ Stewart, CA Blindauer, S Berezenko, D Sleep, D Tooth, PJ Sadler
The FEBS journal 272 (2), 353-362, 2005
1432005
Saccharomyces Cerevisiae Strains that Overexpress Heterologous Proteins
D Sleep, GP Belfield, DJ Ballance, J Steven, S Jones, LR Evans, PD Moir, ...
Bio/technology 9 (2), 183-187, 1991
1401991
High purity albumin and method of producing
AR Goodey, D Sleep, H Van Urk, S Berezenko, JR Woodrow, RA Johnson, ...
US Patent 5,728,553, 1998
1311998
Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity
C Finnis, N Dodsworth, CE Pollitt, G Carr, D Sleep
European journal of biochemistry 212 (1), 201-210, 1993
961993
Modulation of Chaperone Gene Expression in Mutagenized Saccharomyces cerevisiae Strains Developed for Recombinant Human Albumin Production Results in …
T Payne, C Finnis, LR Evans, DJ Mead, SV Avery, DB Archer, D Sleep
Applied and environmental microbiology 74 (24), 7759-7766, 2008
902008
Albumin fusion proteins
DJ Ballance, D Sleep, CP Prior, H Sadeghi, AJ Turner
US Patent 7,482,013, 2009
862009
A molecular mechanism for modulating plasma Zn speciation by fatty acids
J Lu, AJ Stewart, D Sleep, PJ Sadler, TJT Pinheiro, CA Blindauer
Journal of the American Chemical Society 134 (3), 1454-1457, 2012
682012
Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin …
JT Andersen, J Cameron, A Plumridge, L Evans, D Sleep, I Sandlie
Journal of Biological Chemistry 288 (33), 24277-24285, 2013
672013
Albumin Fusion Proteins
DJ Ballance, D Sleep, CP Prior, H Sadeghi, AJ Turner
US Patent App. 11/927,593, 2008
662008
Peptide and DNA sequences
AR Goodey, GP Belfield, D Sleep
US Patent 5,302,697, 1994
651994
Human platelet-derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase.
GJ Barton, CP Ponting, G Spraggon, C Finnis, D Sleep
Protein Science: a Publication of the Protein Society 1 (5), 688, 1992
621992
Albumin fusion proteins
D Ballance, D Sleep, C Prior, H Sadeghi, A Turner
US Patent App. 09/832,501, 2003
612003
Albumin Fusion Proteins
DJ Ballance, D Sleep, CP Prior, H Sadeghi, AJ Turner
US Patent 8,946,156, 2015
582015
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