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Hidde Ploegh
Hidde Ploegh
Senior Investigator, Program in Cellular and Molecular Medicine, Boston Children's Hospital
Geverifieerd e-mailadres voor childrens.harvard.edu
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Molecular cell biology
HF Lodish
Macmillan, 2008
133032008
Genome-scale CRISPR-mediated control of gene repression and activation
LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ...
Cell 159 (3), 647-661, 2014
27452014
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
JH Niess, S Brand, X Gu, L Landsman, S Jung, BA McCormick, JM Vyas, ...
Science 307 (5707), 254-258, 2005
19312005
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
EJHJ Wiertz, D Tortorella, M Bogyo, J Yu, W Mothes, TR Jones, ...
Nature 384 (6608), 432-438, 1996
14381996
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
EJHJ Wiertz, TR Jones, L Sun, M Bogyo, HJ Geuze, HL Ploegh
Cell 84 (5), 769-779, 1996
13821996
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
T Maruyama, SK Dougan, MC Truttmann, AM Bilate, JR Ingram, ...
Nature biotechnology 33 (5), 538-542, 2015
13212015
Empty MHC class I molecules come out in the cold
HG Ljunggren, NJ Stam, C Öhlén, JJ Neefjes, P Höglund, MT Heemels, ...
Nature 346 (6283), 476-480, 1990
11531990
Herpes simplex virus turns off the TAP to evade host immunity
A Hill, P Jugovic, lan York, G Russ, J Bennink, J Yewdell, H Ploegh, ...
Nature 375 (6530), 411-415, 1995
10801995
Viral subversion of the immune system
D Tortorella, BE Gewurz, MH Furman, DJ Schust, HL Ploegh
Annual review of immunology 18 (1), 861-926, 2000
10282000
Viral strategies of immune evasion
HL Ploegh
Science 280 (5361), 248-253, 1998
10161998
The known unknowns of antigen processing and presentation
JM Vyas, AG Van der Veen, HL Ploegh
Nature Reviews Immunology 8 (8), 607-618, 2008
9162008
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4− 8+ T cells
L Van Kaer, PG Ashton-Rickardt, HL Ploegh, S Tonegawa
Cell 71 (7), 1205-1214, 1992
8751992
A membrane protein required for dislocation of misfolded proteins from the ER
BN Lilley, HL Ploegh
Nature 429 (6994), 834-840, 2004
8642004
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus
T Nakagawa, W Roth, P Wong, A Nelson, A Farr, J Deussing, ...
Science 280 (5362), 450-453, 1998
8581998
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
YM Kim, MM Brinkmann, ME Paquet, HL Ploegh
Nature 452 (7184), 234-238, 2008
8322008
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
PJ Peters, JJ Neefjes, V Oorschot, HL Ploegh, HJ Geuze
Nature 349 (6311), 669-676, 1991
8231991
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
SM Lehmann, C Krüger, B Park, K Derkow, K Rosenberger, J Baumgart, ...
Nature neuroscience 15 (6), 827-835, 2012
7922012
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum
MH Smith, HL Ploegh, JS Weissman
Science 334 (6059), 1086-1090, 2011
7572011
Multiple associated proteins regulate proteasome structure and function
DS Leggett, J Hanna, A Borodovsky, B Crosas, M Schmidt, RT Baker, ...
Molecular cell 10 (3), 495-507, 2002
7572002
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
HY Cohen, S Lavu, KJ Bitterman, B Hekking, TA Imahiyerobo, C Miller, ...
Molecular cell 13 (5), 627-638, 2004
7482004
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Artikelen 1–20