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Rein Verbeke
Rein Verbeke
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Year
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
L Schoenmaker, D Witzigmann, JA Kulkarni, R Verbeke, G Kersten, ...
International journal of pharmaceutics 601, 120586, 2021
8482021
The dawn of mRNA vaccines: The COVID-19 case
R Verbeke, I Lentacker, SC De Smedt, H Dewitte
Journal of Controlled Release 333, 511-520, 2021
3662021
Three decades of messenger RNA vaccine development
R Verbeke, I Lentacker, SC De Smedt, H Dewitte
Nano Today 28, 100766, 2019
2992019
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA
R Verbeke, I Lentacker, L Wayteck, K Breckpot, M Van Bockstal, ...
Journal of Controlled Release 266, 287-300, 2017
1242017
Innate immune mechanisms of mRNA vaccines
R Verbeke, MJ Hogan, K Loré, N Pardi
Immunity 55 (11), 1993-2005, 2022
1062022
Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon
K Broos, K Van der Jeught, J Puttemans, C Goyvaerts, C Heirman, ...
Molecular Therapy-Nucleic Acids 5, 2016
1022016
Broadening the message: a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells
R Verbeke, I Lentacker, K Breckpot, J Janssens, S Van Calenbergh, ...
ACS nano 13 (2), 1655-1669, 2019
832019
Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment
H Dewitte, R Verbeke, K Breckpot, SC De Smedt, I Lentacker
Nano Today 9 (6), 743-758, 2014
732014
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across
AK Minnaert, H Vanluchene, R Verbeke, I Lentacker, SC De Smedt, ...
Advanced drug delivery reviews 176, 113900, 2021
702021
mRNA in cancer immunotherapy: beyond a source of antigen
L Van Hoecke, R Verbeke, H Dewitte, I Lentacker, K Vermaelen, ...
Molecular cancer 20, 1-14, 2021
612021
Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation
L Raes, S Stremersch, JC Fraire, T Brans, G Goetgeluk, S De Munter, ...
Nano-Micro Letters 12, 1-17, 2020
552020
mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice
L Van Hoecke, R Verbeke, D De Vlieger, H Dewitte, K Roose, ...
Molecular Therapy-Nucleic Acids 20, 777-787, 2020
342020
Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes
RL Mayer, R Verbeke, C Asselman, I Aernout, A Gul, D Eggermont, ...
Nature Communications 13 (1), 6075, 2022
232022
Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures
S Meulewaeter, G Nuytten, MHY Cheng, SC De Smedt, PR Cullis, ...
Journal of Controlled Release 357, 149-160, 2023
192023
Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro
H Dewitte, R Verbeke, K Breckpot, RE Vandenbroucke, C Libert, ...
Journal of controlled release 195, 138-146, 2014
192014
Tri-modal In vivo Imaging of Pancreatic Islets Transplanted Subcutaneously in Mice
S Liang, K Louchami, B Holvoet, R Verbeke, CM Deroose, B Manshian, ...
Molecular Imaging and Biology 20, 940-951, 2018
182018
Exciting times for lipid nanoparticles: How Canadian discoveries are enabling gene therapies
MHY Cheng, CA Brimacombe, R Verbeke, PR Cullis
Molecular pharmaceutics 19 (6), 1663-1668, 2022
112022
Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model
S Saini, H Korf, S Liang, R Verbeke, B Manshian, K Raemdonck, ...
Magnetic Resonance Materials in Physics, Biology and Medicine 32, 295-305, 2019
112019
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium
J Deprez, R Verbeke, S Meulewaeter, I Aernout, H Dewitte, T Decruy, ...
Nature Nanotechnology 18 (11), 1341-1350, 2023
72023
Longitudinal in vivo assessment of host-microbe interactions in a murine model of pulmonary aspergillosis
S Saini, J Poelmans, H Korf, JL Dooley, S Liang, BB Manshian, ...
Iscience 20, 184-194, 2019
72019
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