| Calmodulin supports both inactivation and facilitation of L-type calcium channels RD ZuÈhlke, GS Pitt, K Deisseroth, RW Tsien, H Reuter Nature 399 (6732), 159-162, 1999 | 1103 | 1999 |
| CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation A Hudmon, H Schulman, J Kim, JM Maltez, RW Tsien, GS Pitt The Journal of cell biology 171 (3), 537-547, 2005 | 404 | 2005 |
| Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels GS Pitt, RD Zühlke, A Hudmon, H Schulman, H Reuter, RW Tsien Journal of Biological Chemistry 276 (33), 30794-30802, 2001 | 376 | 2001 |
| Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development GS Pitt, N Milona, J Borleis, KC Lin, RR Reed, PN Devreotes Cell 69 (2), 305-315, 1992 | 351 | 1992 |
| Thermosensory and nonthermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat-sensor domains of a thermoTRP Channel L Zhong, A Bellemer, H Yan, K Honjo, J Robertson, RY Hwang, GS Pitt, ... Cell reports 1 (1), 43-55, 2012 | 259 | 2012 |
| Progress in understanding and treating SCN2A-mediated disorders SJ Sanders, AJ Campbell, JR Cottrell, RS Moller, FF Wagner, ... Trends in neurosciences 41 (7), 442-456, 2018 | 254 | 2018 |
| Ca2+-sensitive inactivation and facilitation of L-type Ca2+ channels both depend on specific amino acid residues in a consensus calmodulin-binding motif in theα1C subunit RD Zühlke, GS Pitt, RW Tsien, H Reuter Journal of Biological Chemistry 275 (28), 21121-21129, 2000 | 242 | 2000 |
| Targeted epigenetic remodeling of endogenous loci by CRISPR/Cas9-based transcriptional activators directly converts fibroblasts to neuronal cells JB Black, AF Adler, HG Wang, AM D’Ippolito, HA Hutchinson, TE Reddy, ... Cell stem cell 19 (3), 406-414, 2016 | 235 | 2016 |
| Identification of the components controlling inactivation of voltage-gated Ca2+ channels J Kim, S Ghosh, DA Nunziato, GS Pitt Neuron 41 (5), 745-754, 2004 | 221 | 2004 |
| Calmodulin mediates Ca2+ sensitivity of sodium channels J Kim, S Ghosh, H Liu, M Tateyama, RS Kass, GS Pitt Journal of Biological Chemistry 279 (43), 45004-45012, 2004 | 200 | 2004 |
| KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin S Ghosh, DA Nunziato, GS Pitt Circulation research 98 (8), 1048-1054, 2006 | 195 | 2006 |
| Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics G Liu, A Papa, AN Katchman, SI Zakharov, D Roybal, JA Hennessey, ... Nature 577 (7792), 695-700, 2020 | 191 | 2020 |
| Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin C Wang, BC Chung, H Yan, SY Lee, GS Pitt Structure 20 (7), 1167-1176, 2012 | 175 | 2012 |
| Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium. M Pupillo, A Kumagai, GS Pitt, RA Firtel, PN Devreotes Proceedings of the National Academy of Sciences 86 (13), 4892-4896, 1989 | 134 | 1989 |
| A spatially resolved brain region-and cell type-specific isoform atlas of the postnatal mouse brain A Joglekar, A Prjibelski, A Mahfouz, P Collier, S Lin, AK Schlusche, ... Nature Communications 12 (1), 463, 2021 | 132 | 2021 |
| Fibroblast Growth Factor Homologous Factor 13 Regulates Na+ Channels and Conduction Velocity in Murine Hearts C Wang, JA Hennessey, RD Kirkton, C Wang, V Graham, RS Puranam, ... Circulation research 109 (7), 775-782, 2011 | 131 | 2011 |
| FGF12 is a candidate Brugada syndrome locus JA Hennessey, CA Marcou, C Wang, EQ Wei, C Wang, DJ Tester, ... Heart rhythm 10 (12), 1886-1894, 2013 | 113 | 2013 |
| Calmodulin and CaMKII as molecular switches for cardiac ion channels GS Pitt Cardiovascular research 73 (4), 641-647, 2007 | 112 | 2007 |
| Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development inDictyostelium SKO Mann, JM Brown, C Briscoe, C Parent, G Pitt, PN Devreotes, ... Developmental biology 183 (2), 208-221, 1997 | 110 | 1997 |
| Structural analyses of Ca2+/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation C Wang, BC Chung, H Yan, HG Wang, SY Lee, GS Pitt Nature communications 5 (1), 4896, 2014 | 108 | 2014 |
