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Oleksandr Frei
Oleksandr Frei
Verified email at medisin.uio.no
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Year
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
10502022
A global overview of pleiotropy and genetic architecture in complex traits
K Watanabe, S Stringer, O Frei, M Umićević Mirkov, C de Leeuw, ...
Nature genetics 51 (9), 1339-1348, 2019
8792019
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ...
Nature genetics 53 (6), 817-829, 2021
6872021
Common brain disorders are associated with heritable patterns of apparent aging of the brain
T Kaufmann, D van der Meer, NT Doan, E Schwarz, MJ Lund, I Agartz, ...
Nature neuroscience 22 (10), 1617-1623, 2019
3772019
RICOPILI: rapid imputation for COnsortias PIpeLIne
M Lam, S Awasthi, HJ Watson, J Goldstein, G Panagiotaropoulou, ...
Bioinformatics 36 (3), 930-933, 2020
2592020
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
O Frei, D Holland, OB Smeland, AA Shadrin, CC Fan, S Maeland, ...
Nature communications 10 (1), 2417, 2019
2172019
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
OB Smeland, S Bahrami, O Frei, A Shadrin, K O’Connell, J Savage, ...
Molecular psychiatry 25 (4), 844-853, 2020
2092020
The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology
OB Smeland, O Frei, AM Dale, OA Andreassen
Nature Reviews Neurology 16 (7), 366-379, 2020
1482020
Bigartm: Open source library for regularized multimodal topic modeling of large collections
K Vorontsov, O Frei, M Apishev, P Romov, M Dudarenko
Analysis of Images, Social Networks and Texts: 4th International Conference …, 2015
1422015
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
D Holland, O Frei, R Desikan, CC Fan, AA Shadrin, OB Smeland, ...
PLoS Genetics 16 (5), e1008612, 2020
1362020
Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors
N Mullins, JE Kang, AI Campos, JRI Coleman, AC Edwards, H Galfalvy, ...
Biological psychiatry 91 (3), 313-327, 2022
1292022
Understanding the genetic determinants of the brain with MOSTest
D van der Meer, O Frei, T Kaufmann, AA Shadrin, A Devor, OB Smeland, ...
Nature communications 11 (1), 3512, 2020
1272020
Identification of genetic loci jointly influencing schizophrenia risk and the cognitive traits of verbal-numerical reasoning, reaction time, and general cognitive function
OB Smeland, O Frei, K Kauppi, WD Hill, W Li, Y Wang, F Krull, F Bettella, ...
JAMA psychiatry 74 (10), 1065-1075, 2017
1222017
Discovery of shared genomic loci using the conditional false discovery rate approach
OB Smeland, O Frei, A Shadrin, K O’Connell, CC Fan, S Bahrami, ...
Human genetics 139 (1), 85-94, 2020
1162020
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
D Van der Meer, J Rokicki, T Kaufmann, A Córdova-Palomera, ...
Molecular psychiatry 25 (11), 3053-3065, 2020
1112020
Genetic overlap between schizophrenia and volumes of hippocampus, putamen, and intracranial volume indicates shared molecular genetic mechanisms
OB Smeland, Y Wang, O Frei, W Li, DP Hibar, B Franke, F Bettella, ...
Schizophrenia bulletin 44 (4), 854-864, 2018
1032018
Shared genetic loci between body mass index and major psychiatric disorders: a genome-wide association study
S Bahrami, NE Steen, A Shadrin, K O’Connell, O Frei, F Bettella, ...
JAMA psychiatry 77 (5), 503-512, 2020
952020
The genetic architecture of human cortical folding
D Van Der Meer, T Kaufmann, AA Shadrin, C Makowski, O Frei, D Roelfs, ...
Science advances 7 (51), eabj9446, 2021
592021
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
OB Smeland, Y Wang, MT Lo, W Li, O Frei, A Witoelar, M Tesli, DA Hinds, ...
Scientific reports 7 (1), 2222, 2017
582017
Genome-wide association analysis of Parkinson’s disease and schizophrenia reveals shared genetic architecture and identifies novel risk loci
OB Smeland, A Shadrin, S Bahrami, I Broce, M Tesli, O Frei, KV Wirgenes, ...
Biological psychiatry 89 (3), 227-235, 2021
562021
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