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Deepak Almeida
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Targeting DnaN for tuberculosis therapy using novel griselimycins
A Kling, P Lukat, DV Almeida, A Bauer, E Fontaine, S Sordello, ...
Science 348 (6239), 1106-1112, 2015
3222015
Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates …
KA Cohen, T Abeel, A Manson McGuire, CA Desjardins, V Munsamy, ...
PLoS medicine 12 (9), e1001880, 2015
2922015
Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis
E Nuermberger, S Tyagi, R Tasneen, KN Williams, D Almeida, I Rosenthal, ...
Antimicrobial agents and chemotherapy 52 (4), 1522-1524, 2008
2312008
Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis
D Almeida, T Ioerger, S Tyagi, SY Li, K Mdluli, K Andries, J Grosset, ...
Antimicrobial agents and chemotherapy 60 (8), 4590-4599, 2016
1972016
Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance
CA Desjardins, KA Cohen, V Munsamy, T Abeel, K Maharaj, BJ Walker, ...
Nature genetics 48 (5), 544-551, 2016
1882016
Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor
S Gupta, S Tyagi, DV Almeida, MC Maiga, NC Ammerman, WR Bishai
American journal of respiratory and critical care medicine 188 (5), 600-607, 2013
1862013
Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis
IM Rosenthal, R Tasneen, CA Peloquin, M Zhang, D Almeida, KE Mdluli, ...
Antimicrobial agents and chemotherapy 56 (8), 4331-4340, 2012
1632012
Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis
E Nuermberger, I Rosenthal, S Tyagi, KN Williams, D Almeida, ...
Antimicrobial agents and chemotherapy 50 (8), 2621-2625, 2006
1592006
Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice
JH Grosset, S Tyagi, DV Almeida, PJ Converse, SY Li, NC Ammerman, ...
American journal of respiratory and critical care medicine 188 (5), 608-612, 2013
1452013
Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis
S Tyagi, NC Ammerman, SY Li, J Adamson, PJ Converse, RV Swanson, ...
Proceedings of the National Academy of Sciences 112 (3), 869-874, 2015
1412015
Incidence of multidrug-resistant tuberculosis in urban and rural India and implications for prevention
D Almeida, C Rodrigues, ZF Udwadia, A Lalvani, GD Gothi, P Mehta, ...
Clinical infectious diseases 36 (12), e152-e154, 2003
1282003
Pharmacokinetics and pharmacodynamics of clofazimine in a mouse model of tuberculosis
RV Swanson, J Adamson, C Moodley, B Ngcobo, NC Ammerman, ...
Antimicrobial agents and chemotherapy 59 (6), 3042-3051, 2015
1062015
Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis
D Almeida, E Nuermberger, R Tasneen, I Rosenthal, S Tyagi, K Williams, ...
Antimicrobial agents and chemotherapy 53 (10), 4178-4184, 2009
1042009
High Incidence of the Beijing Genotype among Multidrug-Resistant Isolates of Mycobacterium tuberculosis in a Tertiary Care Center in Mumbai, India
D Almeida, C Rodrigues, TF Ashavaid, A Lalvani, ZF Udwadia, A Mehta
Clinical infectious diseases 40 (6), 881-886, 2005
902005
Contribution of pretomanid to novel regimens containing bedaquiline with either linezolid or moxifloxacin and pyrazinamide in murine models of tuberculosis
J Xu, SY Li, DV Almeida, R Tasneen, K Barnes-Boyle, PJ Converse, ...
Antimicrobial agents and chemotherapy 63 (5), 10.1128/aac. 00021-19, 2019
772019
Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife?
PJ Converse, EL Nuermberger, DV Almeida, JH Grosset
Future Microbiology 6 (10), 1185-1198, 2011
752011
Isoniazid or moxifloxacin in rifapentine-based regimens for experimental tuberculosis?
IM Rosenthal, M Zhang, D Almeida, JH Grosset, EL Nuermberger
American journal of respiratory and critical care medicine 178 (9), 989-993, 2008
732008
Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering
BM Lee, LK Harold, DV Almeida, L Afriat-Jurnou, HL Aung, BM Forde, ...
PLoS pathogens 16 (2), e1008287, 2020
632020
Pharmacokinetics of Rifampin and Clarithromycin in Patients Treated for Mycobacterium ulcerans Infection
JWC Alffenaar, WA Nienhuis, F De Velde, AT Zuur, AMA Wessels, ...
Antimicrobial agents and chemotherapy 54 (9), 3878-3883, 2010
632010
Clofazimine has delayed antimicrobial activity against Mycobacterium tuberculosis both in vitro and in vivo
NC Ammerman, RV Swanson, A Tapley, C Moodley, B Ngcobo, ...
Journal of Antimicrobial Chemotherapy, dkw417, 2016
562016
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