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Christoph Kaleta
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Fitness and stability of obligate cross-feeding interactions that emerge upon gene loss in bacteria
S Pande, H Merker, K Bohl, M Reichelt, S Schuster, LF De Figueiredo, ...
The ISME journal 8 (5), 953-962, 2014
2582014
Computing the shortest elementary flux modes in genome-scale metabolic networks
LF De Figueiredo, A Podhorski, A Rubio, C Kaleta, JE Beasley, ...
Bioinformatics 25 (23), 3158-3165, 2009
2182009
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
2152020
Less is more: selective advantages can explain the prevalent loss of biosynthetic genes in bacteria
G D'Souza, S Waschina, S Pande, K Bohl, C Kaleta, C Kost
Evolution 68 (9), 2559-2570, 2014
2022014
Metabolic functions of gut microbes associate with efficacy of tumor necrosis factor antagonists in patients with inflammatory bowel diseases
K Aden, A Rehman, S Waschina, WH Pan, A Walker, M Lucio, AM Nunez, ...
Gastroenterology 157 (5), 1279-1292. e11, 2019
1662019
BacArena: Individual-based metabolic modeling of heterogeneous microbes in complex communities
E Bauer, J Zimmermann, F Baldini, I Thiele, C Kaleta
PLoS computational biology 13 (5), e1005544, 2017
1612017
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy
R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ...
Cell 178 (6), 1299-1312. e29, 2019
1482019
Metabolic costs of amino acid and protein production in Escherichia coli
C Kaleta, S Schäuble, U Rinas, S Schuster
Biotechnology journal 8 (9), 1105-1114, 2013
1442013
Can the whole be less than the sum of its parts? Pathway analysis in genome-scale metabolic networks using elementary flux patterns
C Kaleta, LF de Figueiredo, S Schuster
Genome research 19 (10), 1872-1883, 2009
1272009
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs
F Wessely, M Bartl, R Guthke, P Li, S Schuster, C Kaleta
Molecular systems biology 7 (1), 515, 2011
1222011
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing
J Mansfeld, N Urban, S Priebe, M Groth, C Frahm, N Hartmann, ...
Nature communications 6 (1), 10043, 2015
1172015
Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly
P Aramillo Irizar, S Schäuble, D Esser, M Groth, C Frahm, S Priebe, ...
Nature communications 9 (1), 327, 2018
1022018
Can sugars be produced from fatty acids? A test case for pathway analysis tools
LF De Figueiredo, S Schuster, C Kaleta, DA Fell
Bioinformatics 24 (22), 2615-2621, 2008
932008
Integrated network reconstruction, visualization and analysis using YANAsquare
R Schwarz, C Liang, C Kaleta, M Kühnel, E Hoffmann, S Kuznetsov, ...
BMC bioinformatics 8 (1), 1-10, 2007
932007
Pervasive selection for cooperative cross-feeding in bacterial communities
S Germerodt, K Bohl, A Lück, S Pande, A Schröter, C Kaleta, S Schuster, ...
PLoS computational biology 12 (6), e1004986, 2016
852016
Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease
R Häsler, R Sheibani-Tezerji, A Sinha, M Barann, A Rehman, D Esser, ...
Gut 66 (12), 2087-2097, 2017
722017
Computing chemical organizations in biological networks
F Centler, C Kaleta, PS di Fenizio, P Dittrich
Bioinformatics 24 (14), 1611-1618, 2008
612008
The functional repertoire contained within the native microbiota of the model nematode Caenorhabditis elegans
J Zimmermann, N Obeng, W Yang, B Pees, C Petersen, S Waschina, ...
The ISME Journal 14 (1), 26-38, 2020
602020
Natural C. elegans microbiota protects against infection via production of a cyclic lipopeptide of the viscosin group
KAB Kissoyan, M Drechsler, EL Stange, J Zimmermann, C Kaleta, ...
Current Biology 29 (6), 1030-1037. e5, 2019
602019
Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth
G Beuster, K Zarse, C Kaleta, R Thierbach, M Kiehntopf, P Steinberg, ...
Journal of Biological Chemistry 286 (25), 22323-22330, 2011
582011
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