Tom van Wezel
Tom van Wezel
Associate professor, Department of Pathology, Leiden University Medical Center, Netherlands
Verified email at - Homepage
Cited by
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A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3
IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...
Nature genetics 40 (5), 623-630, 2008
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
TC Pansuriya, R Van Eijk, P d'Adamo, MAJH Van Ruler, ML Kuijjer, ...
Nature genetics 43 (12), 1256-1261, 2011
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
M Lombaerts, T Van Wezel, K Philippo, JWF Dierssen, RME Zimmerman, ...
British journal of cancer 94 (5), 661-671, 2006
Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers
CAL Ruivenkamp, T van Wezel, C Zanon, APM Stassen, C Vlcek, ...
Nature genetics 31 (3), 295-300, 2002
Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR
R Van Eijk, J Licht, M Schrumpf, MT Yazdi, D Ruano, GI Forte, ...
PloS one 6 (3), e17791, 2011
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16. 1 (REL), 8q24. 21 and 10p14 (GATA3)
V Enciso-Mora, P Broderick, Y Ma, RF Jarrett, H Hjalgrim, K Hemminki, ...
Nature genetics 42 (12), 1126-1130, 2010
Gene interaction and single gene effects in colon tumour susceptibility in mice
T van Wezel, APM Stassen, CJA Moen, AAM Hart, MA van der Valk, ...
Nature genetics 14 (4), 468-470, 1996
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer
J Drost, R Van Boxtel, F Blokzijl, T Mizutani, N Sasaki, V Sasselli, J de Ligt, ...
Science 358 (6360), 234-238, 2017
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer
JN Kloth, J Oosting, T van Wezel, K Szuhai, J Knijnenburg, A Gorter, ...
BMC genomics 8 (1), 53, 2007
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...
The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic …
LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ...
Gut 60 (11), 1544-1553, 2011
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK
PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ...
Gastroenterology 147 (1), 196-208. e13, 2014
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression
AM Pittman, S Naranjo, E Webb, P Broderick, EH Lips, T van Wezel, ...
Genome research 19 (6), 987-993, 2009
Reliable high-throughput genotyping and loss-of-heterozygosity detection in formalin-fixed, paraffin-embedded tumors using single nucleotide polymorphism arrays
EH Lips, JWF Dierssen, R van Eijk, J Oosting, PHC Eilers, ...
Cancer research 65 (22), 10188-10191, 2005
Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment
YM Schrage, IH Briaire-de Bruijn, NFCC de Miranda, J van Oosterwijk, ...
Cancer Research 69 (15), 6216-6222, 2009
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer
MS Reimers, E Bastiaannet, RE Langley, R van Eijk, RLP van Vlierberghe, ...
JAMA internal medicine 174 (5), 732-739, 2014
Chromosome 8q23. 3 and 11q23. 1 variants modify colorectal cancer risk in Lynch syndrome
JT Wijnen, RM Brohet, R Van Eijk, S Jagmohan–Changur, A Middeldorp, ...
Gastroenterology 136 (1), 131-137, 2009
HNPCC versus sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
JWF Dierssen, NFCC de Miranda, S Ferrone, M van Puijenbroek, ...
BMC cancer 7 (1), 33, 2007
Identification of MEN1 and HRPT2 somatic mutations in paraffin‐embedded (sporadic) parathyroid carcinomas
CJ Haven, M Van Puijenbroek, MH Tan, BT Teh, GJ Fleuren, T Van Wezel, ...
Clinical endocrinology 67 (3), 370-376, 2007
Allelic variation at the 8q23. 3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H
AM Pittman, S Naranjo, SE Jalava, P Twiss, Y Ma, B Olver, A Lloyd, ...
PLoS Genet 6 (9), e1001126, 2010
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