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Alfred Bothwell
Alfred Bothwell
Professor of Immunobiology
Geverifieerd e-mailadres voor yale.edu
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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region
ALM Bothwell, M Paskind, M Reth, T Imanishi-Kari, K Rajewsky, ...
Cell 24 (3), 625-637, 1981
8201981
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends
FW Alt, ALM Bothwell, M Knapp, E Siden, E Mather, M Koshland, ...
Cell 20 (2), 293-301, 1980
7081980
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity
T Welte, SSM Zhang, T Wang, Z Zhang, DGT Hesslein, Z Yin, A Kano, ...
Proceedings of the National Academy of Sciences 100 (4), 1879-1884, 2003
4952003
T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity
M Corr, AE Slanetz, LF Boyd, MT Jelonek, S Khilko, BK Al-Ramadi, ...
Science 265 (5174), 946-949, 1994
4671994
In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse
JS Schechner, AK Nath, L Zheng, MS Kluger, CCW Hughes, ...
Proceedings of the National Academy of Sciences 97 (16), 9191-9196, 2000
4362000
An autoantibody to single‐stranded DNA: comparison of the three‐dimensional structures of the unliganded Fab and a deoxynucleotide–Fab complex
JN Herron, XM He, DW Ballard, PR Blier, PE Pace, ALM Bothwell, ...
Proteins: Structure, Function, and Bioinformatics 11 (3), 159-175, 1991
3321991
Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28
AG Murray, MM Khodedoust, JS Pober, ALM Bothwell
Immunity 1 (1), 57-63, 1994
3181994
Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation
J Das, G Ren, L Zhang, AI Roberts, X Zhao, ALM Bothwell, L Van Kaer, ...
Journal of Experimental Medicine 206 (11), 2407-2416, 2009
2972009
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain
FW Alt, V Enea, ALM Bothwell, D Baltimore
Cell 21 (1), 1-12, 1980
2901980
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis
WJ Chae, TF Gibson, D Zelterman, L Hao, O Henegariu, ALM Bothwell
Proceedings of the National Academy of Sciences 107 (12), 5540-5544, 2010
2682010
Interplay between DNA repair and inflammation, and the link to cancer
D Kidane, WJ Chae, J Czochor, KA Eckert, PM Glazer, ALM Bothwell, ...
Critical reviews in biochemistry and molecular biology 49 (2), 116-139, 2014
2092014
Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59
WC Hahn, E Menu, ALM Bothwell, PJ Sims, BE Bierer
Science 256 (5065), 1805-1807, 1992
2051992
The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases
JM Choi, ALM Bothwell
Molecules and cells 33 (3), 217-222, 2012
1982012
Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments
DGT Hesslein, DL Pflugh, D Chowdhury, ALM Bothwell, R Sen, ...
Genes & development 17 (1), 37-42, 2003
1962003
Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins.
F Zhang, B Crise, B Su, Y Hou, JK Rose, A Bothwell, K Jacobson
The Journal of cell biology 115 (1), 75-84, 1991
1911991
Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.
BK Al-Ramadi, MT Jelonek, LF Boyd, DH Margulies, AL Bothwell
Journal of immunology (Baltimore, Md.: 1950) 155 (2), 662-673, 1995
1821995
Molecular basis of a mouse strain-specific anti-hapten response
DY Loh, ALM Bothwell, ME White-Scharf, T Imanishi-Kari, D Baltimore
Cell 33 (1), 85-93, 1983
1791983
Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds.
KD Khan, K Shuai, G Lindwall, SE Maher, JE Darnell Jr, AL Bothwell
Proceedings of the National Academy of Sciences 90 (14), 6806-6810, 1993
1781993
Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/− γc−/−, and CB-17-scid/bg …
CM Lepus, TF Gibson, SA Gerber, I Kawikova, M Szczepanik, J Hossain, ...
Human immunology 70 (10), 790-802, 2009
1712009
STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation
T Welte, D Leitenberg, BN Dittel, BK Al-Ramadi, B Xie, YE Chin, ...
Science 283 (5399), 222-225, 1999
1711999
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