gregory lesinski
gregory lesinski
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Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner
TA Mace, Z Ameen, A Collins, S Wojcik, M Mair, GS Young, JR Fuchs, ...
Cancer research 73 (10), 3007-3018, 2013
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer
TA Mace, R Shakya, JR Pitarresi, B Swanson, CW McQuinn, S Loftus, ...
Gut 67 (2), 320-332, 2018
β-Blockers and survival among Danish patients with malignant melanoma: a population-based cohort study
S Lemeshow, HT Sørensen, G Phillips, EV Yang, S Antonsen, AH Riis, ...
Cancer Epidemiology and Prevention Biomarkers 20 (10), 2273-2279, 2011
Novel vaccine strategies to T-independent antigens
GB Lesinski, MAJ Westerink
Journal of microbiological methods 47 (2), 135-149, 2001
Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice
BL Mundy-Bosse, GB Lesinski, AC Jaime-Ramirez, K Benninger, M Khan, ...
Cancer research 71 (15), 5101-5110, 2011
The antitumor effects of IFN-α are abrogated in a STAT1-deficient mouse
GB Lesinski, M Anghelina, J Zimmerer, T Bakalakos, B Badgwell, ...
The Journal of clinical investigation 112 (2), 170-180, 2003
A randomized phase 2 trial of bevacizumab with or without daily low-dose interferon alfa-2b in metastatic malignant melanoma
KA Varker, JE Biber, C Kefauver, R Jensen, A Lehman, D Young, H Wu, ...
Annals of surgical oncology 14 (8), 2367-2376, 2007
Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy
BL Mundy-Bosse, GS Young, T Bauer, E Binkley, M Bloomston, MA Bill, ...
Cancer Immunology, Immunotherapy 60 (9), 1269-1279, 2011
Enhanced bioavailability of lycopene when consumed as cis‐isomers from tangerine compared to red tomato juice, a randomized, cross‐over clinical trial
JL Cooperstone, RA Ralston, KM Riedl, TC Haufe, RM Schweiggert, ...
Molecular nutrition & food research 59 (4), 658-669, 2015
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
L Lin, S Deangelis, E Foust, J Fuchs, C Li, PK Li, EB Schwartz, ...
Molecular cancer 9 (1), 1-10, 2010
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity
MA Bill, JR Fuchs, C Li, J Yui, C Bakan, DM Benson, EB Schwartz, ...
Molecular cancer 9 (1), 1-12, 2010
Vaccines against polysaccharide antigens
GB Lesinski, J Westerink
Current Drug Targets-Infectious Disorders 1 (3), 325-334, 2001
A DNA vaccine encoding a peptide mimic of Streptococcus pneumoniae serotype 4 capsular polysaccharide induces specific anti-carbohydrate antibodies in Balb/c mice
GB Lesinski, SL Smithson, N Srivastava, D Chen, G Widera, ...
Vaccine 19 (13-14), 1717-1726, 2001
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines
MA Bill, C Bakan, DM Benson, J Fuchs, G Young, GB Lesinski
Molecular cancer therapeutics 8 (9), 2726-2735, 2009
Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy
GB Lesinski, SV Kondadasula, T Crespin, L Shen, K Kendra, M Walker, ...
Journal of the National Cancer Institute 96 (17), 1331-1342, 2004
Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines
MA Bill, C Nicholas, TA Mace, JP Etter, C Li, EB Schwartz, JR Fuchs, ...
PloS one 7 (8), e40724, 2012
α-Mangostin: anti-inflammatory activity and metabolism by human cells
F Gutierrez-Orozco, C Chitchumroonchokchai, GB Lesinski, ...
Journal of agricultural and food chemistry 61 (16), 3891-3900, 2013
Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells
TA Mace, AL Collins, SE Wojcik, CM Croce, GB Lesinski, M Bloomston
Journal of surgical research 184 (2), 855-860, 2013
Randomized phase 2 trial of the oncolytic virus pelareorep (Reolysin) in upfront treatment of metastatic pancreatic adenocarcinoma
AM Noonan, MR Farren, SM Geyer, Y Huang, S Tahiri, D Ahn, S Mikhail, ...
Molecular Therapy 24 (6), 1150-1158, 2016
A mathematical model for pancreatic cancer growth and treatments
Y Louzoun, C Xue, GB Lesinski, A Friedman
Journal of theoretical biology 351, 74-82, 2014
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