Plinio Cabrera Casarotto
Plinio Cabrera Casarotto
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Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ...
Cell 184 (5), 1299-1313. e19, 2021
Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
PC Casarotto, FV Gomes, LBM Resstel, FS Guimarães
Behavioural pharmacology 21 (4), 353-358, 2010
Opposing roles for cannabinoid receptor type-1 (CB1) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats
PC Casarotto, ALB Terzian, DC Aguiar, H Zangrossi, FS Guimaraes, ...
Neuropsychopharmacology 37 (2), 478-486, 2012
Repeated paroxetine treatment reverses anhedonia induced in rats by chronic mild stress or dexamethasone
PC Casarotto, R Andreatini
European Neuropsychopharmacology 17 (11), 735-742, 2007
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
R Moliner, M Girych, CA Brunello, V Kovaleva, C Biojone, G Enkavi, ...
Nature Neuroscience 26 (6), 1032-1041, 2023
Isoflurane produces antidepressant effects and induces TrkB signaling in rodents
H Antila, M Ryazantseva, D Popova, P Sipilä, R Guirado, S Kohtala, ...
Scientific reports 7 (1), 7811, 2017
Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice
FV Gomes, PC Casarotto, LBM Resstel, FS Guimarães
Progress in Neuro-Psychopharmacology and Biological Psychiatry 35 (2), 434-438, 2011
Cannabidiol reverses the mCPP‐induced increase in marble‐burying behavior
M Nardo, PC Casarotto, FV Gomes, FS Guimaraes
Fundamental & clinical pharmacology 28 (5), 544-550, 2014
Antidepressant-and anticompulsive-like effects of purinergic receptor blockade: involvement of nitric oxide
VS Pereira, PC Casarotto, VA Hiroaki-Sato, AG Sartim, FS Guimarães, ...
European Neuropsychopharmacology 23 (12), 1769-1778, 2013
Interplay between nitric oxide and brain-derived neurotrophic factor in neuronal plasticity
C Biojone, P Cabrera Casarotto, S Regiane Joca, E Castrén
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2015
Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine shows antiviral activity against the novel variants in vitro
SM Fred, S Kuivanen, H Ugurlu, PC Casarotto, L Levanov, K Saksela, ...
Frontiers in Pharmacology 12, 755600, 2022
Beyond good and evil: a putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment
CRAF Diniz, PC Casarotto, L Resstel, SRL Joca
Neuroscience & Biobehavioral Reviews, 2018
Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2
SM Fred, L Laukkanen, CA Brunello, L Vesa, H Göös, I Cardon, R Moliner, ...
Journal of Biological Chemistry 294 (48), 18150-18161, 2019
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN
CRAF Diniz, PC Casarotto, SM Fred, C Biojone, E Castrén, SRL Joca
Neuropharmacology 135, 163-171, 2018
Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine
E Pryazhnikov, E Mugantseva, P Casarotto, J Kolikova, SM Fred, ...
Scientific reports 8 (1), 6464, 2018
Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons
A Lesnikova, PC Casarotto, SM Fred, M Voipio, F Winkel, A Steinzeig, ...
Journal of Neuroscience 41 (5), 972-980, 2021
Panicolytic-like effect of BDNF in the rat dorsal periaqueductal grey matter: the role of 5-HT and GABA
PC Casarotto, VC de Bortoli, FM de Aguiar Corrêa, LB Moraes Resstel, ...
International Journal of Neuropsychopharmacology 13 (5), 573-582, 2010
Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters
MV Fogaça, SF Lisboa, DC Aguiar, FA Moreira, FV Gomes, PC Casarotto, ...
Brazilian Journal of Medical and Biological Research 45, 357-365, 2012
Anti-aversive effects of the atypical antipsychotic, aripiprazole, in animal models of anxiety
C Biojone, PC Casarotto, LB Resstel, H Zangrossi Jr, FS Guimaraes, ...
Journal of Psychopharmacology 25 (6), 801-807, 2011
Anti-inflammatory treatment with FTY720 starting after onset of symptoms reverses synaptic deficits in an AD mouse model
GI Kartalou, AR Salgueiro-Pereira, T Endres, A Lesnikova, P Casarotto, ...
International Journal of Molecular Sciences 21 (23), 8957, 2020
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