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Lei Sun
Lei Sun
Verified email at purdue.edu
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Year
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
H Yang, M Yang, Y Ding, Y Liu, Z Lou, Z Zhou, L Sun, L Mo, S Ye, H Pang, ...
Proceedings of the National Academy of Sciences 100 (23), 13190-13195, 2003
11012003
The 3.8 Å resolution cryo-EM structure of Zika virus
D Sirohi, Z Chen, L Sun, T Klose, TC Pierson, MG Rossmann, RJ Kuhn
Science 352 (6284), 467-470, 2016
9012016
RNA structure maps across mammalian cellular compartments
L Sun, FM Fazal, P Li, JP Broughton, B Lee, L Tang, W Huang, ET Kool, ...
Nature structural & molecular biology 26 (4), 322-330, 2019
2002019
Crystal structure of methyl parathion hydrolase from Pseudomonas sp. WBC-3
YJ Dong, M Bartlam, L Sun, YF Zhou, ZP Zhang, CG Zhang, Z Rao, ...
Journal of molecular biology 353 (3), 655-663, 2005
1762005
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
L Sun, P Li, X Ju, J Rao, W Huang, L Ren, S Zhang, T Xiong, K Xu, X Zhou, ...
Cell 184 (7), 1865-1883. e20, 2021
1582021
Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection
L Sun, LN Young, X Zhang, SP Boudko, A Fokine, E Zbornik, ...
Nature 505 (7483), 432-435, 2014
1172014
Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution
L Sun, X Zhang, S Gao, PA Rao, V Padilla-Sanchez, Z Chen, S Sun, ...
Nature communications 6 (1), 7548, 2015
1112015
Integrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivity
P Li, Y Wei, M Mei, L Tang, L Sun, W Huang, J Zhou, C Zou, S Zhang, ...
Cell host & microbe 24 (6), 875-886. e5, 2018
1032018
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
Y Zhao, X Du, Y Duan, X Pan, Y Sun, T You, L Han, Z Jin, W Shang, J Yu, ...
Protein & cell 12 (11), 877-888, 2021
1012021
Refinement and analysis of the mature Zika virus cryo-EM structure at 3.1 Å resolution
M Sevvana, F Long, AS Miller, T Klose, G Buda, L Sun, RJ Kuhn, ...
Structure 26 (9), 1169-1177. e3, 2018
1012018
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
C Li, W Zhan, Z Yang, C Tu, G Hu, X Zhang, W Song, S Du, Y Zhu, ...
Cell 185 (8), 1389-1401. e18, 2022
952022
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures
L Sun, K Xu, W Huang, YT Yang, P Li, L Tang, T Xiong, QC Zhang
Cell research 31 (5), 495-516, 2021
742021
Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-Å resolution and its relevance to the assembly of icosahedral viruses
Z Chen, L Sun, Z Zhang, A Fokine, V Padilla-Sanchez, D Hanein, W Jiang, ...
Proceedings of the National Academy of Sciences 114 (39), E8184-E8193, 2017
692017
Structural basis for the function of DCN-1 in protein Neddylation
X Yang, J Zhou, L Sun, Z Wei, J Gao, W Gong, RM Xu, Z Rao, Y Liu
Journal of Biological Chemistry 282 (34), 24490-24494, 2007
682007
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2
S Zhang, W Huang, L Ren, X Ju, M Gong, J Rao, L Sun, P Li, Q Ding, ...
Cell Research 32 (1), 9-23, 2022
562022
Crystal structure of the pyridoxal‐5′‐phosphate‐dependent serine dehydratase from human liver
L Sun, M Bartlam, Y Liu, H Pang, Z Rao
Protein science 14 (3), 791-798, 2005
442005
Advances and opportunities in RNA structure experimental determination and computational modeling
J Zhang, Y Fei, L Sun, QC Zhang
Nature methods 19 (10), 1193-1207, 2022
422022
Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain
M Levisson, L Sun, S Hendriks, P Swinkels, T Akveld, JB Bultema, ...
Journal of Molecular Biology 385 (3), 949-962, 2009
422009
Structure of the ribosome associating GTPase HflX
H Wu, L Sun, F Blombach, SJJ Brouns, APL Snijders, K Lorenzen, ...
Proteins: Structure, Function, and Bioinformatics 78 (3), 705-713, 2010
342010
Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3
L Sun, Y Dong, Y Zhou, M Yang, C Zhang, Z Rao, X Zhang
Acta Crystallographica Section D: Biological Crystallography 60 (5), 954-956, 2004
342004
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