Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian … SI Hamdy, M Hiratsuka, K Narahara, M El‐Enany, N Moursi, MSE Ahmed, ... British journal of clinical pharmacology 53 (6), 596-603, 2002 | 218 | 2002 |
Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR‐1 in the Egyptian population SI Hamdy, M Hiratsuka, K Narahara, N Endo, M El‐Enany, N Moursi, ... British journal of clinical pharmacology 55 (6), 560-569, 2003 | 206 | 2003 |
Allele and genotype frequencies of CYP2B6 and CYP3A5 in the Japanese population M Hiratsuka, Y Takekuma, N Endo, K Narahara, S Hamdy, Y Kishikawa, ... European journal of clinical pharmacology 58, 417-421, 2002 | 198 | 2002 |
Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6. 2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57) K Sakuyama, T Sasaki, S Ujiie, K Obata, M Mizugaki, M Ishikawa, ... Drug Metabolism and Disposition 36 (12), 2460-2467, 2008 | 193 | 2008 |
An optimized prediction framework to assess the functional impact of pharmacogenetic variants Y Zhou, S Mkrtchian, M Kumondai, M Hiratsuka, VM Lauschke The pharmacogenomics journal 19 (2), 115-126, 2019 | 129 | 2019 |
In vitro assessment of the allelic variants of cytochrome P450 M Hiratsuka Drug metabolism and pharmacokinetics 27 (1), 68-84, 2012 | 121 | 2012 |
Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population M Hiratsuka, T Inoue, F Omori, Y Agatsuma, M Mizugaki Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 448 (1 …, 2000 | 114 | 2000 |
Functional characterization of 32 CYP2C9 allelic variants Y Niinuma, T Saito, M Takahashi, C Tsukada, M Ito, N Hirasawa, ... The pharmacogenomics journal 14 (2), 107-114, 2014 | 112 | 2014 |
Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT* 2–* 24) S Ujiie, T Sasaki, M Mizugaki, M Ishikawa, M Hiratsuka Pharmacogenetics and genomics 18 (10), 887-893, 2008 | 107 | 2008 |
Gender difference in association between polymorphism of serotonin transporter gene regulatory region and anxiety T Mizuno, M Aoki, Y Shimada, M Inoue, K Nakaya, T Takahashi, ... Journal of psychosomatic research 60 (1), 91-97, 2006 | 106 | 2006 |
Influence of sex on propofol metabolism, a pilot study: implications for propofol anesthesia I Loryan, M Lindqvist, I Johansson, M Hiratsuka, I Van Der Heiden, ... European journal of clinical pharmacology 68, 397-406, 2012 | 103 | 2012 |
Functional characterization of human xanthine oxidase allelic variants M Kudo, T Moteki, T Sasaki, Y Konno, S Ujiie, A Onose, M Mizugaki, ... Pharmacogenetics and genomics 18 (3), 243-251, 2008 | 103 | 2008 |
Genotyping of the N-acetyltransferase2 polymorphism in the prediction of adverse drug reactions to isoniazid in Japanese patients M Hiratsuka, Y Kishikawa, Y Takekuma, M Matsuura, K Narahara, T Inoue, ... Drug metabolism and pharmacokinetics 17 (4), 357-362, 2002 | 99 | 2002 |
Association between cancer risk and drug-metabolizing enzyme gene (CYP2A6, CYP2A13, CYP4B1, SULT1A1, GSTM1 and GSTT1) polymorphisms in cases of lung cancer in Japan Y Tamaki, T Arai, H Sugimura, T Sasaki, M Honda, Y Muroi, Y Matsubara, ... Drug metabolism and pharmacokinetics 26 (5), 516-522, 2011 | 89 | 2011 |
Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics M Santos, M Niemi, M Hiratsuka, M Kumondai, M Ingelman-Sundberg, ... Genetics in Medicine 20 (6), 622-629, 2018 | 84 | 2018 |
Genotyping of four genetic polymorphisms in the CYP1A2 gene in the Egyptian population SI Hamdy, M Hiratsuka, K Narahara, N Endo, M El‐Enany, N Moursi, ... British journal of clinical pharmacology 55 (3), 321-324, 2003 | 71 | 2003 |
Structure of human holocarboxylase synthetase gene and mutation spectrum of holocarboxylase synthetase deficiency X Yang, Y Aoki, X Li, O Sakamoto, M Hiratsuka, S Kure, S Taheri, ... Human genetics 109, 526-534, 2001 | 71 | 2001 |
Rapid detection of CYP2C9* 3 alleles by real-time fluorescence PCR based on SYBR Green M Hiratsuka, Y Agatsuma, M Mizugaki Molecular genetics and metabolism 68 (3), 357-362, 1999 | 68 | 1999 |
Adenovirus-mediated in utero gene transfer in mice and guinea pigs: tissue distribution of recombinant adenovirus determined by quantitative TaqMan–polymerase chain reaction assay M Senoo, Y Matsubara, K Fujii, Y Nagasaki, M Hiratsuka, S Kure, ... Molecular genetics and metabolism 69 (4), 269-276, 2000 | 67 | 2000 |
Functional characterization of wild-type and 49 CYP2D6 allelic variants for N-desmethyltamoxifen 4-hydroxylation activity Y Muroi, T Saito, M Takahashi, K Sakuyama, Y Niinuma, M Ito, C Tsukada, ... Drug metabolism and pharmacokinetics 29 (5), 360-366, 2014 | 62 | 2014 |