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Nenad Svrzikapa
Nenad Svrzikapa
University of Oxford, Harvard University, Wave Life Sciences
Geverifieerd e-mailadres voor g.harvard.edu
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High-quality binary protein interaction map of the yeast interactome network
H Yu, P Braun, MA Yıldırım, I Lemmens, K Venkatesan, J Sahalie, ...
Science 322 (5898), 104-110, 2008
16022008
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
J Tabernero, GI Shapiro, PM LoRusso, A Cervantes, GK Schwartz, ...
Cancer discovery 3 (4), 406-417, 2013
6742013
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
SW Oh, A Mukhopadhyay, N Svrzikapa, F Jiang, RJ Davis, ...
Proceedings of the National Academy of Sciences 102 (12), 4494-4499, 2005
5782005
Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans
D Dupuy, N Bertin, CA Hidalgo, K Venkatesan, D Tu, D Lee, J Rosenberg, ...
Nature biotechnology 25 (6), 663-668, 2007
3352007
Next-generation sequencing to generate interactome datasets
H Yu, L Tardivo, S Tam, E Weiner, F Gebreab, C Fan, N Svrzikapa, ...
Nature methods 8 (6), 478-480, 2011
2892011
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah, ...
Nature biotechnology 35 (9), 845-851, 2017
2032017
'Edgetic'perturbation of a C. elegans BCL2 ortholog
M Dreze, B Charloteaux, S Milstein, PO Vidalain, MA Yildirim, Q Zhong, ...
Nature methods 6 (11), 843-849, 2009
812009
'Edgetic'perturbation of a C. elegans BCL2 ortholog
M Dreze, B Charloteaux, S Milstein, PO Vidalain, MA Yildirim, Q Zhong, ...
Nature methods 6 (11), 843-849, 2009
812009
An antibiotic selection marker for nematode transgenesis
R Giordano-Santini, S Milstein, N Svrzikapa, D Tu, R Johnsen, D Baillie, ...
nature methods 7 (9), 721-723, 2010
732010
Chiral control
D Butler, N Iwamoto, N Svrzikapa, GL Verdine, I ZLATEV
US Patent 9,982,257, 2018
552018
In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction (HIT qRT-PCR)
Y Landesman, N Svrzikapa, A Cognetta, X Zhang, BR Bettencourt, ...
Silence 1 (1), 1-14, 2010
522010
Phase I dose-escalation study of ALN-VSP02, a novel RNAi therapeutic for solid tumors with liver involvement.
A Cervantes, M Alsina, J Tabernero, JR Infante, P LoRusso, G Shapiro, ...
Journal of Clinical Oncology 29 (15_suppl), 3025-3025, 2011
442011
Meena; Standley, SM; Lu, G.; Apponi, LH; et al. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah
Nat. Biotechnol 35 (9), 845-851, 2017
352017
Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans
MM Grabowski, N Svrzikapa, HA Tissenbaum
Mechanisms of ageing and development 126 (12), 1314-1321, 2005
342005
Meena, SM Standley, G. Lu, LH Apponi, M. Frank-Kamenetsky, JJ Zhang, C. Vargeese, GL Verdine, Control of phosphorothioate stereochemistry substantially increases the efficacy …
N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah
Nat. Biotechnol 35 (9), 2017
282017
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov 3 (4): 406–417. doi: 10.1158/2159-8290
J Tabernero, GI Shapiro, PM LoRusso, A Cervantes, GK Schwartz, ...
CD-12-0429, 2013
262013
Chiral control
DCD Butler, N Iwamoto, N Svrzikapa, GL Verdine, I Zlatev
US Patent 10,590,413, 2020
192020
Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome
K Salehi-Ashtiani, C Lin, T Hao, Y Shen, D Szeto, X Yang, L Ghamsari, ...
Genome Research 19 (12), 2334-2342, 2009
192009
Chiral design
D Butler, N Iwamoto, N Svrzikapa, GL Verdine, I Zlatev
US Patent 10,160,969, 2018
162018
Oligonucleotide compositions and methods thereof
C Vargeese, N Svrzikapa, S Mohapatra, CJ Francis, GL Verdine, ...
US Patent 10,479,995, 2019
132019
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