| Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase A Rossi, P Kapahi, G Natoli, T Takahashi, Y Chen, M Karin, MG Santoro Nature 403 (6765), 103-108, 2000 | 1553 | 2000 |
| Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway P Kapahi, BM Zid, T Harper, D Koslover, V Sapin, S Benzer Current Biology 14 (10), 885-890, 2004 | 1252 | 2004 |
| With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging P Kapahi, D Chen, AN Rogers, SD Katewa, PWL Li, EL Thomas, L Kockel Cell metabolism 11 (6), 453-465, 2010 | 641 | 2010 |
| MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 555 | 2015 |
| 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila BM Zid, AN Rogers, SD Katewa, MA Vargas, MC Kolipinski, TA Lu, ... Cell 139 (1), 149-160, 2009 | 504 | 2009 |
| Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans KZ Pan, JE Palter, AN Rogers, A Olsen, D Chen, GJ Lithgow, P Kapahi Aging cell 6 (1), 111-119, 2007 | 457 | 2007 |
| Inhibition of NF-κB activation by arsenite through reaction with a critical cysteine in the activation loop of IκB kinase P Kapahi, T Takahashi, G Natoli, SR Adams, Y Chen, RY Tsien, M Karin Journal of Biological Chemistry 275 (46), 36062-36066, 2000 | 420 | 2000 |
| Cellular senescence: a link between cancer and age-related degenerative disease? J Campisi, JK Andersen, P Kapahi, S Melov Seminars in cancer biology 21 (6), 354-359, 2011 | 369 | 2011 |
| Positive correlation between mammalian life span and cellular resistance to stress P Kapahi, ME Boulton, TBL Kirkwood Free Radical Biology and Medicine 26 (5-6), 495-500, 1999 | 360 | 1999 |
| Allocrine modulation of feeding behavior by the sex peptide of Drosophila GB Carvalho, P Kapahi, DJ Anderson, S Benzer Current Biology 16 (7), 692-696, 2006 | 241 | 2006 |
| HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans D Chen, EL Thomas, P Kapahi PLoS Genet 5 (5), e1000486, 2009 | 238 | 2009 |
| Late‐life rapamycin treatment reverses age‐related heart dysfunction JM Flynn, MN O'Leary, CA Zambataro, EC Academia, MP Presley, ... Aging cell 12 (5), 851-862, 2013 | 211 | 2013 |
| Detection of a circulating form of vascular cell adhesion molecule‐1: raised levels in rheumatoid arthritis and systemic lupus erythematosus SM Wellicome, P Kapahi, JC Mason, Y Lebranchu, H Yarwood, ... Clinical & Experimental Immunology 92 (3), 412-418, 1993 | 191 | 1993 |
| From discoveries in ageing research to therapeutics for healthy ageing J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman, E Verdin Nature 571 (7764), 183-192, 2019 | 181 | 2019 |
| Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus … JC Mason, P Kapahi, DO Haskard Arthritis & Rheumatism: Official Journal of the American College of …, 1993 | 178 | 1993 |
| Oxidative stress and gene expression: The AP‐1 and NF‐κB connections M Karin, T Takahashi, P Kapahi, M Delhase, Y Chen, C Makris, ... Biofactors 15 (2‐4), 87-89, 2001 | 175 | 2001 |
| SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease J Shin, M He, Y Liu, S Paredes, L Villanova, K Brown, X Qiu, N Nabavi, ... Cell reports 5 (3), 654-665, 2013 | 171 | 2013 |
| Compensatory ingestion upon dietary restriction in Drosophila melanogaster GB Carvalho, P Kapahi, S Benzer Nature methods 2 (11), 813-815, 2005 | 162 | 2005 |
| Dietary restriction and lifespan: lessons from invertebrate models P Kapahi, M Kaeberlein, M Hansen Ageing research reviews 39, 3-14, 2017 | 153 | 2017 |
| Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype RM Laberge, L Zhou, MR Sarantos, F Rodier, A Freund, PLJ de Keizer, ... Aging cell 11 (4), 569-578, 2012 | 140 | 2012 |
Simon MelovBuck Institute for Research on AgingVerified email at buckinstitute.org
