Hannes Hentze
Hannes Hentze
Associate Director, Translational Sciences, EDDC, A*STAR
Verified email at vivology.org - Homepage
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DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells
S Jahr, H Hentze, S Englisch, D Hardt, FO Fackelmayer, RD Hesch, ...
Cancer research 61 (4), 1659-1665, 2001
Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies
H Hentze, PL Soong, ST Wang, BW Phillips, TC Putti, NR Dunn
Stem cell research 2 (3), 198-210, 2009
Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin‐like protein‐1
AB Choo, HL Tan, SN Ang, WJ Fong, A Chin, J Lo, L Zheng, H Hentze, ...
Stem Cells 26 (6), 1454-1463, 2008
The generation of six clinical-grade human embryonic stem cell lines
JM Crook, TT Peura, L Kravets, AG Bosman, JJ Buzzard, R Horne, ...
Cell stem cell 1 (5), 490-494, 2007
Cell therapy and the safety of embryonic stem cell-derived grafts
H Hentze, R Graichen, A Colman
Trends in biotechnology 25 (1), 24-32, 2007
Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin
H Hentze, XY Lin, MSK Choi, AG Porter
Cell Death & Differentiation 10 (9), 956-968, 2003
Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage
BW Phillips, H Hentze, WL Rust, QP Chen, H Chipperfield, EK Tan, ...
Stem cells and development 16 (4), 561-578, 2007
SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies
S Hart, KC Goh, V Novotny-Diermayr, CY Hu, H Hentze, YC Tan, B Madan, ...
Leukemia 25 (11), 1751-1759, 2011
Apoptosis in the absence of poly-(ADP-ribose) polymerase
M Leist, B Single, G Künstle, C Volbracht, H Hentze, P Nicotera
Biochemical and biophysical research communications 233 (2), 518-522, 1997
Concanavalin A hepatotoxicity in mice: Tumor necrosis factor–mediated organ failure independent of caspase‐3–like protease activation
G Künstle, H Hentze, PG Germann, G Tiegs, T Meergans, A Wendel
Hepatology 30 (5), 1241-1251, 1999
SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer
V Novotny-Diermayr, K Sangthongpitag, CY Hu, X Wu, N Sausgruber, ...
Molecular cancer therapeutics 9 (3), 642-652, 2010
Ajoene, an experimental anti-leukemic drug: mechanism of cell death
VM Dirsch, DSM Antlsperger, H Hentze, AM Vollmar
Leukemia 16 (1), 74-83, 2002
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice
H Hentze, F Gantner, SA Kolb, A Wendel
The American journal of pathology 156 (6), 2045-2056, 2000
CD95‐mediated murine hepatic apoptosis requires an intact glutathione status
H Hentze, G Künstle, C Volbracht, W Ertel, A Wendel
Hepatology 30 (1), 177-185, 1999
Glutathione dependence of caspase-8 activation at the death-inducing signaling complex
H Hentze, I Schmitz, M Latta, A Krueger, PH Krammer, A Wendel
Journal of Biological Chemistry 277 (7), 5588-5595, 2002
An experimental study of low-pressure premixed pyrrole/oxygen/argon flames with tunable synchrotron photoionization
Z Tian, Y Li, T Zhang, A Zhu, Z Cui, F Qi
Combustion and flame 151 (1-2), 347-365, 2007
The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML
V Novotny-Diermayr, S Hart, KC Goh, A Cheong, LC Ong, H Hentze, ...
Blood cancer journal 2 (5), e69-e69, 2012
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy
M Leist, S Bremer, P Brundin, J Hescheler, A Kirkeby, KH Krause, ...
Altex 25 (3), 163-190, 2008
Inhibition of caspase activity prevents CD95‐mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity
GA Wanner, L Mica, E Wanner‐Schmid, SA Kolb, H Hentze, O Trentz, ...
The FASEB journal 13 (10), 1239-1248, 1999
In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells
H Hentze, F Schwoebel, S Lund, M Kehl, W Ertel, A Wendel, M Jäättelä, ...
Biochemical and biophysical research communications 283 (5), 1111-1117, 2001
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