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Axel Schambach
Axel Schambach
Full Professor, Hannover Medical School
Geverifieerd e-mailadres voor mh-hannover.de
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Skin tissue generation by laser cell printing
L Koch, A Deiwick, S Schlie, S Michael, M Gruene, V Coger, D Zychlinski, ...
Biotechnology and bioengineering 109 (7), 1855-1863, 2012
5522012
Gene therapy for Wiskott-Aldrich syndrome—long-term efficacy and genotoxicity
CJ Braun, K Boztug, A Paruzynski, M Witzel, A Schwarzer, M Rothe, ...
Science translational medicine 6 (227), 227ra33-227ra33, 2014
5292014
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors
U Modlich, S Navarro, D Zychlinski, T Maetzig, S Knoess, MH Brugman, ...
Molecular Therapy 17 (11), 1919-1928, 2009
4212009
A modified γ-retrovirus vector for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina, SY Pai, HB Gaspar, M Armant, CC Berry, S Blanche, ...
New England Journal of Medicine 371 (15), 1407-1417, 2014
3972014
Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity
U Modlich, J Bohne, M Schmidt, C Von Kalle, S Knöss, A Schambach, ...
Blood 108 (8), 2545-2553, 2006
3702006
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
J Wang, Q Sun, Y Morita, H Jiang, A Groß, A Lechel, K Hildner, ...
Cell 148 (5), 1001-1014, 2012
3402012
Physiological promoters reduce the genotoxic risk of integrating gene vectors
D Zychlinski, A Schambach, U Modlich, T Maetzig, J Meyer, E Grassman, ...
Molecular therapy 16 (4), 718-725, 2008
3312008
Long noncoding RNA Chast promotes cardiac remodeling
J Viereck, R Kumarswamy, A Foinquinos, K Xiao, P Avramopoulos, ...
Science translational medicine 8 (326), 326ra22-326ra22, 2016
3212016
Gene therapy on the move
KB Kaufmann, H Büning, A Galy, A Schambach, M Grez
EMBO molecular medicine 5 (11), 1642-1661, 2013
3112013
The phenotype of human STK4 deficiency
H Abdollahpour, G Appaswamy, D Kotlarz, J Diestelhorst, R Beier, ...
Blood, The Journal of the American Society of Hematology 119 (15), 3450-3457, 2012
2922012
Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming
E Warlich, J Kuehle, T Cantz, MH Brugman, T Maetzig, M Galla, ...
Molecular Therapy 19 (4), 782-789, 2011
2872011
Advantages and applications of CAR-expressing natural killer cells
W Glienke, R Esser, C Priesner, JD Suerth, A Schambach, WS Wels, ...
Frontiers in pharmacology 6, 21, 2015
2452015
Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors
A Schambach, H Wodrich, M Hildinger, J Bohne, HG Kräusslich, C Baum
Molecular therapy 2 (5), 435-445, 2000
2452000
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway
J Skokowa, D Lan, BK Thakur, F Wang, K Gupta, G Cario, AM Brechlin, ...
Nature medicine 15 (2), 151-158, 2009
2352009
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
J Skokowa, G Cario, M Uenalan, A Schambach, M Germeshausen, ...
Nature medicine 12 (10), 1191-1197, 2006
2152006
Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic …
F Zhang, SI Thornhill, SJ Howe, M Ulaganathan, A Schambach, J Sinclair, ...
Blood, The Journal of the American Society of Hematology 110 (5), 1448-1457, 2007
2142007
Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine–DNA methyltransferase in hematopoietic cells
A Schambach, J Bohne, S Chandra, E Will, GP Margison, DA Williams, ...
Molecular Therapy 13 (2), 391-400, 2006
2102006
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome
D Kotlarz, N Ziętara, G Uzel, T Weidemann, CJ Braun, J Diestelhorst, ...
Journal of Experimental Medicine 210 (3), 433-443, 2013
1972013
X-SCID transgene leukaemogenicity
AJ Thrasher, HB Gaspar, C Baum, U Modlich, A Schambach, F Candotti, ...
Nature 443 (7109), E5-E6, 2006
1902006
Gene insertion into genomic safe harbors for human gene therapy
EP Papapetrou, A Schambach
Molecular Therapy 24 (4), 678-684, 2016
1872016
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