|Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization|
H Do, A Dobrovic
Clinical chemistry 61 (1), 64-71, 2015
|High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies|
H Do, M Krypuy, PL Mitchell, SB Fox, A Dobrovic
BMC cancer 8 (1), 1-14, 2008
|Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing|
SQ Wong, J Li, AYC Tan, R Vedururu, JMB Pang, H Do, J Ellul, K Doig, ...
BMC medical genomics 7 (1), 1-10, 2014
|Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase|
H Do, A Dobrovic
Oncotarget 3 (5), 546, 2012
|DNA methylation biomarkers in cancer: progress towards clinical implementation|
T Mikeska, C Bock, H Do, A Dobrovic
Expert review of molecular diagnostics 12 (5), 473-487, 2012
|Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell …|
RJ Young, K Waldeck, C Martin, JH Foo, DP Cameron, L Kirby, H Do, ...
Pigment cell & melanoma research 27 (4), 590-600, 2014
|GRIDSS: sensitive and specific genomic rearrangement detection using positional de Bruijn graph assembly|
DL Cameron, J Schröder, JS Penington, H Do, R Molania, A Dobrovic, ...
Genome research 27 (12), 2050-2060, 2017
|HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer|
L Da Silva, PT Simpson, CE Smart, S Cocciardi, N Waddell, A Lane, ...
Breast Cancer Research 12 (4), 1-13, 2010
|Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates|
H Do, SQ Wong, J Li, A Dobrovic
Clinical chemistry 59 (9), 1376-1383, 2013
|Combination osimertinib and gefitinib in C797S and T790M EGFR-mutated non–small cell lung cancer|
S Arulananda, H Do, A Musafer, P Mitchell, A Dobrovic, T John
Journal of Thoracic Oncology 12 (11), 1728-1732, 2017
|Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver|
C Emmanuel, YE Chiew, J George, D Etemadmoghadam, MS Anglesio, ...
Clinical cancer research 20 (24), 6618-6630, 2014
|Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies|
H Do, A Dobrovic
Molecular cancer 8 (1), 1-11, 2009
|Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome|
AM Lim, H Do, RJ Young, SQ Wong, C Angel, M Collins, EA Takano, ...
International journal of cancer 135 (4), 887-895, 2014
|Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting|
H Do, B Solomon, PL Mitchell, SB Fox, A Dobrovic
BMC research notes 1 (1), 1-5, 2008
|BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.|
MC Andrews, A Behren, F Chionh, J Mariadason, LJ Vella, H Do, ...
Journal of clinical oncology: official journal of the American Society of …, 2013
|A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma|
H Do, NC Wong, C Murone, T John, B Solomon, PL Mitchell, A Dobrovic
Scientific reports 4 (1), 1-8, 2014
|Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours|
SQ Wong, J Li, R Salemi, KE Sheppard, H Do, RW Tothill, GA McArthur, ...
Scientific reports 3 (1), 1-10, 2013
|A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma|
A Richter, F Grieu, A Carrello, B Amanuel, K Namdarian, A Rynska, ...
Scientific reports 3 (1), 1-9, 2013
|Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors|
M Anaka, C Hudson, PH Lo, H Do, OL Caballero, ID Davis, A Dobrovic, ...
BMC medical genomics 6 (1), 1-13, 2013
|Temporal changes of EGFR mutations and T790M levels in tumour and plasma DNA following AZD9291 treatment|
PL Chia, H Do, A Morey, P Mitchell, A Dobrovic, T John
Lung Cancer 98, 29-32, 2016