| Developments in the CCP4 molecular-graphics project L Potterton, S McNicholas, E Krissinel, J Gruber, K Cowtan, P Emsley, ... Acta Crystallographica Section D: Biological Crystallography 60 (12), 2288-2294, 2004 | 706 | 2004 |
| The mitochondrial free radical theory of ageing—where do we stand J Gruber, S Schaffer, B Halliwell Front Biosci 13 (17), 6554-6579, 2008 | 231 | 2008 |
| Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans JAN Gruber, SY Tang, B Halliwell Annals of the New York Academy of Sciences 1100 (1), 530-542, 2007 | 226 | 2007 |
| WNT signaling in disease LF Ng, P Kaur, N Bunnag, J Suresh, ICH Sung, QH Tan, J Gruber, ... Cells 8 (8), 826, 2019 | 204 | 2019 |
| The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease LF Ng, J Gruber, IK Cheah, CK Goo, WF Cheong, G Shui, KP Sit, ... Free Radical Biology and Medicine 71, 390-401, 2014 | 161 | 2014 |
| Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein− protein interaction: structure− activity studies leading to improved potency IR Hardcastle, J Liu, E Valeur, A Watson, SU Ahmed, TJ Blackburn, ... Journal of medicinal chemistry 54 (5), 1233-1243, 2011 | 161 | 2011 |
| The DrugAge database of aging‐related drugs D Barardo, D Thornton, H Thoppil, M Walsh, S Sharifi, S Ferreira, A Anžič, ... Aging cell 16 (3), 594-597, 2017 | 149 | 2017 |
| Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing J Gruber, S Fong, CB Chen, S Yoong, G Pastorin, S Schaffer, I Cheah, ... Biotechnology advances 31 (5), 563-592, 2013 | 149 | 2013 |
| Is uric acid protective or deleterious in acute ischemic stroke? A prospective cohort study RCS Seet, K Kasiman, J Gruber, SY Tang, MC Wong, HM Chang, ... Atherosclerosis 209 (1), 215-219, 2010 | 143 | 2010 |
| Deceptively simple but simply deceptive–Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects J Gruber, LF Ng, SK Poovathingal, B Halliwell FEBS letters 583 (21), 3377-3387, 2009 | 128 | 2009 |
| Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans? PBL Pun, J Gruber, SY Tang, S Schaffer, RLS Ong, S Fong, LF Ng, ... Biogerontology 11, 17-30, 2010 | 112 | 2010 |
| Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans B Qabazard, L Li, J Gruber, MT Peh, LF Ng, SD Kumar, P Rose, CH Tan, ... Antioxidants & redox signaling 20 (16), 2621-2630, 2014 | 98 | 2014 |
| Mitochondrial changes in ageing Caenorhabditis elegans–what do we learn from superoxide dismutase knockouts? J Gruber, LF Ng, S Fong, YT Wong, SA Koh, CB Chen, G Shui, ... PloS one 6 (5), e19444, 2011 | 95 | 2011 |
| Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model S Fong, E Teo, LF Ng, CB Chen, LN Lakshmanan, SY Tsoi, PK Moore, ... Scientific reports 6 (1), 33781, 2016 | 88 | 2016 |
| Drug synergy slows aging and improves healthspan through IGF and SREBP lipid signaling TD Admasu, KC Batchu, D Barardo, LF Ng, VYM Lam, L Xiao, ... Developmental cell 47 (1), 67-79. e5, 2018 | 80 | 2018 |
| Elevation of oxidative-damage biomarkers during aging in F2 hybrid mice: protection by chronic oral intake of resveratrol YT Wong, J Gruber, AM Jenner, MPE Ng, R Ruan, FEH Tay Free Radical Biology and Medicine 46 (6), 799-809, 2009 | 77 | 2009 |
| Allantoin in Human Plasma, Serum, and Nasal-Lining Fluids as a Biomarker of Oxidative Stress: Avoiding Artifacts and Establishing Real in vivo Concentrations J Gruber, SY Tang, AM Jenner, I Mudway, A Blomberg, A Behndig, ... Antioxidants & redox signaling 11 (8), 1767-1776, 2009 | 70 | 2009 |
| Lack of blinding of outcome assessors in animal model experiments implies risk of observer bias S Bello, LT Krogsbøll, J Gruber, ZJ Zhao, D Fischer, A Hróbjartsson Journal of clinical epidemiology 67 (9), 973-983, 2014 | 66 | 2014 |
| Developmental drift and the role of Wnt signaling in aging J Gruber, Z Yee, NS Tolwinski Cancers 8 (8), 73, 2016 | 63 | 2016 |
| Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta E Teo, S Ravi, D Barardo, HS Kim, S Fong, A Cazenave-Gassiot, TY Tan, ... Elife 8, e50069, 2019 | 60 | 2019 |
Li Fang NGHead of Laboratories, Head of Research and Compliance,Yale-NUS CollegeVerified email at nus.edu.sg
