John y Chiang
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Bile acids: regulation of synthesis: thematic review series: bile acids
JYL Chiang
Journal of lipid research 50 (10), 1955-1966, 2009
Bile acid metabolism and signaling
JYL Chiang
Comprehensive physiology 3 (3), 1191, 2013
Bile acid signaling in metabolic disease and drug therapy
T Li, JYL Chiang
Pharmacological reviews 66 (4), 948-983, 2014
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms
JYL Chiang
Journal of hepatology 40 (3), 539-551, 2004
Bile acid regulation of gene expression: roles of nuclear hormone receptors
JYL Chiang
Endocrine reviews 23 (4), 443-463, 2002
Regulation of cholesterol 7α-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRα)
JYL Chiang, R Kimmel, D Stroup
Gene 262 (1-2), 257-265, 2001
Regulation of bile acid synthesis
JYL Chiang
Frontiers in Bioscience-Landmark 3 (4), 176-193, 1998
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α‐hydroxylase gene expression
KH Song, T Li, E Owsley, S Strom, JYL Chiang
Hepatology 49 (1), 297-305, 2009
Farnesoid X receptor responds to bile acids and represses cholesterol 7α-hydroxylase gene (CYP7A1) transcription
JYL Chiang, R Kimmel, C Weinberger, D Stroup
Journal of Biological Chemistry 275 (15), 10918-10924, 2000
Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice
B Kong, L Wang, JYL Chiang, Y Zhang, CD Klaassen, GL Guo
Hepatology 56 (3), 1034-1043, 2012
Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism
P Pathak, C Xie, RG Nichols, JM Ferrell, S Boehme, KW Krausz, ...
Hepatology 68 (4), 1574-1588, 2018
Bile acid metabolism in liver pathobiology
JYL Chiang, JM Ferrell
Gene expression 18 (2), 71, 2018
Transcriptional regulation of the human sterol 12α-hydroxylase gene (CYP8B1): roles of hepatocyte nuclear factor 4α in mediating bile acid repression
M Zhang, JYL Chiang
Journal of Biological Chemistry 276 (45), 41690-41699, 2001
Bile acids as metabolic regulators
T Li, JYL Chiang
Current opinion in gastroenterology 31 (2), 159, 2015
Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA.
YC Li, DP Wang, JY Chiang
Journal of Biological Chemistry 265 (20), 12012-12019, 1990
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7α-hydroxylase gene transcription
T Li, JYL Chiang
American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (1 …, 2005
Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis
T Li, M Matozel, S Boehme, B Kong, LM Nilsson, G Guo, E Ellis, ...
Hepatology 53 (3), 996-1006, 2011
Transgenic expression of cholesterol 7α‐hydroxylase in the liver prevents high‐fat diet–induced obesity and insulin resistance in mice
T Li, E Owsley, M Matozel, P Hsu, CM Novak, JYL Chiang
Hepatology 52 (2), 678-690, 2010
Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat
WM Pandak, YC Li, JY Chiang, EJ Studer, EC Gurley, DM Heuman, ...
Journal of Biological Chemistry 266 (6), 3416-3421, 1991
Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription
M Marrapodi, JYL Chiang
Journal of lipid research 41 (4), 514-520, 2000
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