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Gijs Zom
Gijs Zom
Scientific Writer, Genmab
Geverifieerd e-mailadres voor genmab.com
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Efficient induction of antitumor immunity by synthetic toll-like receptor ligand–peptide conjugates
GG Zom, S Khan, CM Britten, V Sommandas, MGM Camps, NM Loof, ...
Cancer immunology research 2 (8), 756-764, 2014
1202014
TLR ligand–peptide conjugate vaccines: toward clinical application
GGP Zom, S Khan, DV Filippov, F Ossendorp
Advances in immunology 114, 177-201, 2012
1062012
Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication
GG Zom, MM Willems, S Khan, TC van der Sluis, JW Kleinovink, ...
Journal for immunotherapy of cancer 6, 1-13, 2018
712018
TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients
GG Zom, MJP Welters, NM Loof, R Goedemans, S Lougheed, ...
Oncotarget 7 (41), 67087, 2016
632016
N-Tetradecylcarbamyl Lipopeptides as Novel Agonists for Toll-like Receptor 2
MM Willems, GG Zom, S Khan, N Meeuwenoord, CJM Melief, ...
Journal of medicinal chemistry 57 (15), 6873-6878, 2014
462014
Enapotamab vedotin, an AXL-specific antibody-drug conjugate, shows preclinical antitumor activity in non-small cell lung cancer
LA Koopman, MG Terp, GG Zom, ML Janmaat, K Jacobsen, ...
JCI insight 4 (21), 2019
442019
Dual synthetic peptide conjugate vaccine simultaneously triggers TLR2 and NOD2 and activates human dendritic cells
GG Zom, MM Willems, NJ Meeuwenoord, NRM Reintjens, E Tondini, ...
Bioconjugate Chemistry 30 (4), 1150-1161, 2019
332019
Lipophilic muramyl dipeptide–antigen conjugates as immunostimulating agents
MM Willems, GG Zom, N Meeuwenoord, S Khan, F Ossendorp, ...
ChemMedChem 11 (2), 190-198, 2016
312016
Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule
GG Zom, DV Filippov, GA van der Marel, HS Overkleeft, CJ Melief, ...
Oncoimmunology 3 (7), e947892, 2014
242014
HBV-Derived Synthetic Long Peptide Can Boost CD4+ and CD8+ T-Cell Responses in Chronic HBV Patients Ex Vivo
Y Dou, N van Montfoort, A van den Bosch, RA de Man, GG Zom, ...
The Journal of infectious diseases 217 (5), 827-839, 2018
212018
Design, automated synthesis and immunological evaluation of NOD2-ligand–antigen conjugates
MM Willems, GG Zom, N Meeuwenoord, FA Ossendorp, HS Overkleeft, ...
Beilstein Journal of Organic Chemistry 10 (1), 1445-1453, 2014
162014
Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients
Y Dou, DTSL Jansen, A van Den Bosch, RA de Man, N van Montfoort, ...
Antiviral Research 178, 104746, 2020
132020
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with …
FM Speetjens, MJP Welters, M Slingerland, MIE van Poelgeest, ...
Journal for ImmunoTherapy of Cancer 10 (10), 2022
112022
Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates. Cancer Immunol. Res. 2014; 2: 756–764. doi: 10.1158/2326-6066
GG Zom, S Khan, CM Britten, V Sommandas, MG Camps, NM Loof, ...
CIR-13-0223.[Abstract][CrossRef][Google Scholar], 0
11
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens
SC Oostindie, DA Rinaldi, GG Zom, MJ Wester, D Paulet, K Al-Tamimi, ...
Nature Biotechnology 40 (10), 1509-1519, 2022
102022
Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates. Cancer Immunol Res. 2014; 2 (8): 756–764. doi: 10.1158/2326-6066
GG Zom, S Khan, CM Britten, V Sommandas, MG Camps, NM Loof, ...
CIR-13-0223.[Abstract][CrossRef][Google Scholar], 0
10
Efficient induction of antitumor immunity by synthetic toll-like receptor ligand-peptide conjugates. Cancer Immunol Res 2 (8): 756–764. doi: 10.1158/2326-6066
GG Zom, S Khan, CM Britten, V Sommandas, MG Camps, NM Loof, ...
CIR-13-0223, 2014
52014
Phase I trial to determine safety and immunogenicity of amplivant, a synthetic toll-like receptor 2 ligand, conjugated to two HPV16 E6 synthetic long peptides.
FM Speetjens, MJP Welters, M Slingerland, P de Vos van Steenwijk, ...
Journal of Clinical Oncology 39 (15_suppl), 2614-2614, 2021
32021
T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors
J Middelburg, M Sluijter, G Schaap, B Göynük, K Lloyd, V Ovcinnikovs, ...
Nature Communications 15 (1), 48, 2024
2024
Tumor-nonspecific vaccines improve the efficacy of CD3 bispecific antibody therapy in solid tumors
J Middelburg, M Sluijter, G Schaap, B Göynük, K Lloyd, V Ovcinnikovs, ...
2023
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