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Peter M.J. Quinn
Peter M.J. Quinn
Principal Investigator, Associate Research Scientist and NYSCF Druckenmiller Fellow
Geverifieerd e-mailadres voor cumc.columbia.edu - Homepage
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PINK1/PARKIN signalling in neurodegeneration and neuroinflammation.
PMJ Quinn, PI Moreira, AF Ambrósio, CH Alves
Acta Neuropathol Commun, 2020
732020
Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis
LP Pellissier, CH Alves, PM Quinn, RM Vos, N Tanimoto, DMS Lundvig, ...
PLoS genetics 9 (12), e1003976, 2013
732013
Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models
LP Pellissier, PM Quinn, CH Alves, RM Vos, J Klooster, JG Flannery, ...
Human molecular genetics 24 (11), 3104-3118, 2015
592015
Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5
PM Quinn, TM Buck, AA Mulder, C Ohonin, CH Alves, RM Vos, M Bialecka, ...
Stem Cell Reports, 2019
482019
The CRB1 complex: following the trail of crumbs to a feasible gene therapy strategy
PM Quinn, LP Pellissier, J Wijnholds
Frontiers in neuroscience 11, 175, 2017
442017
Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype
PM Quinn, AA Mulder, CH Alves, M Desrosiers, SI de Vries, J Klooster, ...
Human Molecular Genetics, 2019
272019
CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function
PM Quinn, CH Alves, J Klooster, J Wijnholds
Human Molecular Genetics 27 (18), 2018
262018
Production of iPS-derived human retinal organoids for use in transgene expression assays
PM Quinn, TM Buck, C Ohonin, HMM Mikkers, J Wijnholds
Retinal Gene Therapy, 261-273, 2018
192018
Organoids and organ chips in ophthalmology
N Manafi, F Shokri, K Achberger, M Hirayama, MH Mohammadi, ...
The Ocular Surface, 2020
142020
Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective
PMJ Quinn, J Wijnholds
Genes, 2019
132019
Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa
S Caruso, J Ryu, PMJ Quinn, SH Tsang
The Journal of Clinical Investigation, 2020
92020
The role of small molecules and their effect on the molecular mechanisms of early retinal organoid development
PE Wagstaff, A Heredero Berzal, CJF Boon, PMJ Quinn, A ten Asbroek, ...
International Journal of Molecular Sciences, 2021
52021
NTPDase2 as a surface marker to isolate flow cytometrically a Müller glial cell enriched population from dissociated neural retinae
PM Quinn, RM Hoek, CH Alves, B Hooibrink, J Wijnholds
Journal of Neuroscience and Neurosurgery 1 (4), 2018
42018
CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa
WH Wu, YT Tsai, IW Huang, CH Cheng, CW Hsu, X Cui, J Ryu, ...
Molecular Therapy, 2022
32022
Role of Oxidative Stress in Retinal Ganglion Cells degenerations
EYC Kang, PK Liu, YT Wen, PMJ Quinn, SR Levi, NK Wang, RK Tsai
Antioxidants, 2021
32021
Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration
Y Tsai, Y Li, J Ryu, P Su, C Cheng, W Wu, Y Li, PMJ Quinn, KW Leong, ...
The American Journal of Human Genetics, 2021
32021
Phase transition specified by a binary code patterns the vertebrate eye cup
R Balasubramanian, X Min, PMJ Quinn, Q Lo Giudice, C Tao, K Polanco, ...
Science Advances 7, 2021
22021
Prime Editing for Inherited Retinal Diseases
BLD Costa, SR Levi, E Eulau, YT Tsai, PMJ Quinn
Frontiers In Genome Editing, 2021
22021
Recapitulation of the Human Fetal Crumbs Complex in human iPSCs-derived Retinas and Retinal Pigment Epithelium
PM Quinn, TM Buck, C Alves, C Ohonin, SMC de Sousa Lopes, H Mikkers, ...
Investigative Ophthalmology & Visual Science 58 (8), 3758, 2017
22017
Potency assay for AAV-gene vectors in human iPSCs-derived retinas and donor retinas
TM Buck, PM Quinn, C Alves, E Van Dijk, C Ohonin, CJF Boon, ...
Investigative Ophthalmology & Visual Science 58 (8), 4093, 2017
22017
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Artikelen 1–20