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Stephan Sachs
Stephan Sachs
Verified email at helmholtz-muenchen.de
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Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
L Niu, PE Geyer, NJ Wewer Albrechtsen, LL Gluud, A Santos, S Doll, ...
Molecular systems biology 15 (3), e8793, 2019
2042019
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans
S Sachs, S Zarini, DE Kahn, KA Harrison, L Perreault, T Phang, ...
American Journal of Physiology-Endocrinology and Metabolism 316 (5), E866-E879, 2019
1372019
Targeted pharmacological therapy restores β-cell function for diabetes remission
S Sachs, A Bastidas-Ponce, S Tritschler, M Bakhti, A Böttcher, ...
Nature Metabolism 2 (2), 192-209, 2020
1122020
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice
S Jall, S Sachs, C Clemmensen, B Finan, F Neff, RD DiMarchi, ...
Molecular metabolism 6 (5), 440-446, 2017
1082017
Glucagon regulation of energy expenditure
M Kleinert, S Sachs, KM Habegger, SM Hofmann, TD Müller
International journal of molecular sciences 20 (21), 5407, 2019
872019
A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue
IP Fischer, M Irmler, CW Meyer, SJ Sachs, F Neff, M Hrabě de Angelis, ...
International journal of obesity 42 (3), 507-517, 2018
652018
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, ...
Nature communications 9 (1), 4304, 2018
512018
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors
M Keuper, S Sachs, E Walheim, L Berti, B Raedle, D Tews, ...
Molecular metabolism 6 (10), 1226-1239, 2017
302017
Pharmacological targeting of endoplasmic reticulum stress in pancreatic beta cells
S Bilekova, S Sachs, H Lickert
Trends in pharmacological sciences 42 (2), 85-95, 2021
292021
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
K Fischer, A Fenzl, D Liu, KA Dyar, M Kleinert, M Brielmeier, ...
Nature Communications 11 (1), 2306, 2020
272020
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin
M Keuper, L Berti, B Raedle, S Sachs, A Böhm, L Fritsche, A Fritsche, ...
Molecular Metabolism 20, 28-37, 2019
192019
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet‐induced obese female and male mice
S Sachs, L Niu, P Geyer, S Jall, M Kleinert, A Feuchtinger, K Stemmer, ...
Diabetes, Obesity and Metabolism 23 (1), 195-207, 2021
142021
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
S Jall, M De Angelis, AM Lundsgaard, AM Fritzen, TS Nicolaisen, ...
Diabetologia 63 (6), 1236-1247, 2020
102020
Circulating HDL levels control hypothalamic astrogliosis via apoA-I
A Götz, M Lehti, E Donelan, C Striese, S Cucuruz, S Sachs, CX Yi, ...
Journal of Lipid Research 59 (9), 1649-1659, 2018
92018
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes
NF Chhabra, AL Amend, A Bastidas-Ponce, S Sabrautzki, ...
Molecular metabolism 54, 101334, 2021
62021
Hrabě de Angelis M, Jastroch M, et al. 2019
M Keuper, L Berti, B Raedle, S Sachs, A Böhm, L Fritsche, A Fritsche, ...
Preadipocytes of obese humans display gender-specific bioenergetic responses …, 0
6
GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease
S Sachs, A Götz, B Finan, A Feuchtinger, RD DiMarchi, Y Döring, ...
Cardiovascular diabetology 22 (1), 217, 2023
32023
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and …
D Lutter, S Sachs, M Walter, A Kerege, L Perreault, DE Kahn, AD Wolide, ...
Diabetologia 66 (5), 873-883, 2023
22023
Polypharmakologie als ein neuer Ansatz zur Präzisionsmedizin in der Adipositas-und Diabetestherapie
S Jall, A Götz, MH Tschöp, TD Müller
Adipositas-Ursachen, Folgeerkrankungen, Therapie 12 (02), 76-83, 2018
22018
Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission
S Sachs, A Bastidas-Ponce, S Tritschler, M Bakhti, A Böttcher, ...
Nature metabolism 2 (4), 380, 2020
12020
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