sylvain Ladame
sylvain Ladame
Lecturer in Biosensor Development, Department of Bioengineering, Imperial College London
Verified email at imperial.ac.uk
Title
Cited by
Cited by
Year
Putative DNA Quadruplex Formation within the Human c-kit Oncogene
S Rankin, AP Reszka, J Huppert, M Zloh, GN Parkinson, AK Todd, ...
Journal of the American Chemical Society 127 (30), 10584-10589, 2005
5852005
A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene
H Fernando, AP Reszka, J Huppert, S Ladame, S Rankin, ...
Biochemistry 45 (25), 7854-7860, 2006
4162006
Dynamic combinatorial chemistry: on the road to fulfilling the promise
S Ladame
Organic & biomolecular chemistry 6 (2), 219-226, 2008
2652008
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands
PS Shirude, ER Gillies, S Ladame, F Godde, K Shin-Ya, I Huc, ...
Journal of the American Chemical Society 129 (39), 11890-11891, 2007
1792007
Enhanced chemical synthesis at soft interfaces: A universal reaction-adsorption mechanism in microcompartments
A Fallah-Araghi, K Meguellati, JC Baret, A El Harrak, T Mangeat, ...
Physical review letters 112 (2), 028301, 2014
1652014
Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands
K Jantos, R Rodriguez, S Ladame, PS Shirude, S Balasubramanian
Journal of the American Chemical Society 128 (42), 13662-13663, 2006
1322006
DNA‐templated synthesis of trimethine cyanine dyes: a versatile fluorogenic reaction for sensing G‐quadruplex formation
K Meguellati, G Koripelly, S Ladame
Angewandte Chemie 122 (15), 2798-2802, 2010
1132010
Templated ligand assembly by using G‐quadruplex DNA and dynamic covalent chemistry
AM Whitney, S Ladame, S Balasubramanian
Angewandte Chemie International Edition 43 (9), 1143-1146, 2004
842004
First evidence of a functional interaction between DNA quadruplexes and poly (ADP-ribose) polymerase-1
VA Soldatenkov, AA Vetcher, T Duka, S Ladame
ACS chemical biology 3 (4), 214-219, 2008
752008
G-quadruplex-specific peptide− hemicyanine ligands by partial combinatorial selection
JA Schouten, S Ladame, SJ Mason, MA Cooper, S Balasubramanian
Journal of the American Chemical Society 125 (19), 5594-5595, 2003
752003
Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins
DPN Gonçalves, S Ladame, S Balasubramanian, JKM Sanders
Organic & biomolecular chemistry 4 (17), 3337-3342, 2006
732006
Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates
JE Redman, JM Granadino-Roldan, JA Schouten, S Ladame, AP Reszka, ...
Organic & biomolecular chemistry 7 (1), 76-84, 2009
702009
Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach
S Ladame, AM Whitney, S Balasubramanian
Angewandte Chemie 117 (35), 5882-5885, 2005
692005
Combining G-quadruplex targeting motifs on a single peptide nucleic acid scaffold: a hybrid (3+ 1) PNA-DNA bimolecular quadruplex
A Paul, P Sengupta, Y Krishnan, S Ladame
WILEY-V CH VERLAG GMBH, 2008
662008
Hydrogel-coated microneedle arrays for minimally invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid
D Al Sulaiman, JYH Chang, NR Bennett, H Topouzi, CA Higgins, DJ Irvine, ...
ACS nano 13 (8), 9620-9628, 2019
592019
Synthesis and spectroscopic and DNA-binding properties of fluorogenic acridine-containing cyanine dyes
T Mahmood, A Paul, S Ladame
The Journal of organic chemistry 75 (1), 204-207, 2010
542010
Amplification-free detection of circulating microRNA biomarkers from body fluids based on fluorogenic oligonucleotide-templated reaction between engineered peptide nucleic acid …
GAD Metcalf, A Shibakawa, H Patel, A Sita-Lumsden, A Zivi, N Rama, ...
Analytical chemistry 88 (16), 8091-8098, 2016
512016
Inhibition of human telomerase activity by an engineered zinc finger protein that binds G-quadruplexes
SD Patel, M Isalan, G Gavory, S Ladame, Y Choo, S Balasubramanian
Biochemistry 43 (42), 13452-13458, 2004
512004
Crystal structure of Trypanosoma cruzi glyceraldehyde‐3‐phosphate dehydrogenase complexed with an analogue of 1,3‐bisphospho‐d‐glyceric acid: Selective …
S Ladame, MS Castilho, CHTP Silva, C Denier, V Hannaert, J Périé, ...
European journal of biochemistry 270 (22), 4574-4586, 2003
512003
Oligonucleotide-templated chemical reactions: pushing the boundaries of a nature-inspired process
C Percivalle, JF Bartolo, S Ladame
Organic & biomolecular chemistry 11 (1), 16-26, 2013
492013
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